Sulphanilamide 140
Sulphanilic acid 140
Sulphathiazole 186
Sulphonamide 85, 101, 138, 185
Sulphonation 122, 150, 160, 259, 260
Sulphonic acid 101
Sulphonyl chloride 244
Sulphoxazole 186
Sumatripan 298
Suprafacial 281, 282
Syn addition 198, 199, 208, 266
Syn coplanar conformation 230
Syn elimination 227, 230
Tannic acid 302
Tannins 368, 369
Tartaric acid 50, 56
Tautomerism (keto-enol) 206
Taxol 115, 284, 343, 346, 347
Taxus brevifolia 343, 347
Teratogenic activity 54
Terminal alkyne 108, 109, 111
Termination (radical chain
termination) 192, 194, 203, 204
Tertiary (3
) carbon 65
Terpenoid 347–359
Testosterone 354, 355, 357, 358
Tetrahydrofuran (THF) 80, 81, 143, 152
Tetrahydroisoquinoline 167
Tetraterpenes 350–352
Thalidomide 54
Theobromine 163, 290, 300
Theophylline 163
Thiamine (vitamin B 1 ) 156
Thiazole 145, 155–158
Thiols 78, 79, 243, 250
Thionyl chloride (SOCl 2 ) 70, 93,
Thiophene 145–152
Threonine 179, 182
Thymine 160
Thymol blue 15
Titrant 14
Titration 14
Tocopherol (vitamin E) 197, 343
Tollens’ reagent 271, 309
Toluene 120, 127–129
p-Toluenesulphoate ester 98
p-Toluenesulphonic acid 98
p-Toluenesulphonyl chloride (TsCl) 244,
271, 272
Toluidines 83, 132
Torsional energy 38, 39
Torsional strain 38, 39
Tosylate 244, 245, 271, 272
Tosyl chloride (TsCl) 244, 271, 272
Tosyl (Ts) group 244, 271, 272
Transesterification 98, 249
Transfer RNA (tRNA) 177, 178
Triethylamine 82
2, 3, 4-Trihydroxybutanal 49
Trimethylamine 82
Triphenylphosphine oxide 215
Triple bond 22, 26
Triterpenes 326, 331, 347–350
Triticum sativum 314
Troglitazone (Rezulin) 185
Tropane 291, 293, 294
Tryptamine 290, 297–299
Tryptophan 179, 182
Tyrosine 179, 182
Umbelliferae 363
Umbelliferone 359, 360, 363, 364
Unimolecular reaction 223, 233, 281
Unsaturated hydrocarbon 103–111
Uracil 160, 162
Uric acid 163, 164
Uridine 171
Valence 19
Valence electron 19, 21
Valence shell 21
Valerenic acid 339
Valeric acid 90
Valine 179, 182
Valium 115
van der Walls or London dispersion
forces 29
Vicinal (vic)-dihalides 209–211, 231
Vinyl group 105
Vinyl halides 110, 231, 256
Vinylic carbon 104
Vilsmeier reaction 149, 170
Vinca rosea 284
Vincristine 284
Vioxx 185
Vitamin A 343, 350–352
Vitamin C (ascorbic acid) 197, 318
Vitamin D 353, 355
Vitamin E (a-tocopherol) 197, 343
Vitamin K 343
Volumetric analysis 14
Wagner’s reagent 302
Williamson ether synthesis 81,
238, 239
Water 3, 5, 30, 76
Wittig reagent 107, 215–217
382
INDEX
Sulphanilic acid 140
Sulphathiazole 186
Sulphonamide 85, 101, 138, 185
Sulphonation 122, 150, 160, 259, 260
Sulphonic acid 101
Sulphonyl chloride 244
Sulphoxazole 186
Sumatripan 298
Suprafacial 281, 282
Syn addition 198, 199, 208, 266
Syn coplanar conformation 230
Syn elimination 227, 230
Tannic acid 302
Tannins 368, 369
Tartaric acid 50, 56
Tautomerism (keto-enol) 206
Taxol 115, 284, 343, 346, 347
Taxus brevifolia 343, 347
Teratogenic activity 54
Terminal alkyne 108, 109, 111
Termination (radical chain
termination) 192, 194, 203, 204
Tertiary (3
) carbon 65
Terpenoid 347–359
Testosterone 354, 355, 357, 358
Tetrahydrofuran (THF) 80, 81, 143, 152
Tetrahydroisoquinoline 167
Tetraterpenes 350–352
Thalidomide 54
Theobromine 163, 290, 300
Theophylline 163
Thiamine (vitamin B 1 ) 156
Thiazole 145, 155–158
Thiols 78, 79, 243, 250
Thionyl chloride (SOCl 2 ) 70, 93,
Thiophene 145–152
Threonine 179, 182
Thymine 160
Thymol blue 15
Titrant 14
Titration 14
Tocopherol (vitamin E) 197, 343
Tollens’ reagent 271, 309
Toluene 120, 127–129
p-Toluenesulphoate ester 98
p-Toluenesulphonic acid 98
p-Toluenesulphonyl chloride (TsCl) 244,
271, 272
Toluidines 83, 132
Torsional energy 38, 39
Torsional strain 38, 39
Tosylate 244, 245, 271, 272
Tosyl chloride (TsCl) 244, 271, 272
Tosyl (Ts) group 244, 271, 272
Transesterification 98, 249
Transfer RNA (tRNA) 177, 178
Triethylamine 82
2, 3, 4-Trihydroxybutanal 49
Trimethylamine 82
Triphenylphosphine oxide 215
Triple bond 22, 26
Triterpenes 326, 331, 347–350
Triticum sativum 314
Troglitazone (Rezulin) 185
Tropane 291, 293, 294
Tryptamine 290, 297–299
Tryptophan 179, 182
Tyrosine 179, 182
Umbelliferae 363
Umbelliferone 359, 360, 363, 364
Unimolecular reaction 223, 233, 281
Unsaturated hydrocarbon 103–111
Uracil 160, 162
Uric acid 163, 164
Uridine 171
Valence 19
Valence electron 19, 21
Valence shell 21
Valerenic acid 339
Valeric acid 90
Valine 179, 182
Valium 115
van der Walls or London dispersion
forces 29
Vicinal (vic)-dihalides 209–211, 231
Vinyl group 105
Vinyl halides 110, 231, 256
Vinylic carbon 104
Vilsmeier reaction 149, 170
Vinca rosea 284
Vincristine 284
Vioxx 185
Vitamin A 343, 350–352
Vitamin C (ascorbic acid) 197, 318
Vitamin D 353, 355
Vitamin E (a-tocopherol) 197, 343
Vitamin K 343
Volumetric analysis 14
Wagner’s reagent 302
Williamson ether synthesis 81,
238, 239
Water 3, 5, 30, 76
Wittig reagent 107, 215–217
382
INDEX