Pimarane diterpenoids
Podocarpane diterpenoids
O
O
O
OH
O
O
H
Annonalide
O
OH O
H
O
O
H
Betolide
Prenylgermacrane diterpenoids
Serrulatane and biflorane diterpenoids
OH
Dilophol
OH
O
H
14-Serrulatene-8,18-diol
Sphenolobane diterpenoids
Taxane diterpenoids
O
O
3-Spenolobene-5,16-dione
O OH
O
OAc
H
O
H
O
OH
AcO
O
O
OH
N
O
H
Ph
Ph
Ph
Paclitaxel or Taxol
Tigliane and ingenane diterpenoids
Verrucosane diterpenoids
O
OH
O
H
O
H
O
H
O
H
OH
4β, 9α, 12β, 13α, 16α, 20β-Hexa-hydroxy-1,6-tigliadien-3-one
OH
OH
OH
2β, 9α, 13β-Verrucosanetriol
Xenicane and xeniaphyllane diterpenoids
O
OAc
AcO
AcO
OAc
Xenicin
Botanical sources
Diterpenes are found in nature, mainly in plants, but also in other
natural sources, e.g. micro-organisms and insects. The following table
presents just a few of these sources, and their major diterpenoidal
components.
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CH6 NATURAL PRODUCT CHEMISTRY
Podocarpane diterpenoids
O
O
O
OH
O
O
H
Annonalide
O
OH O
H
O
O
H
Betolide
Prenylgermacrane diterpenoids
Serrulatane and biflorane diterpenoids
OH
Dilophol
OH
O
H
14-Serrulatene-8,18-diol
Sphenolobane diterpenoids
Taxane diterpenoids
O
O
3-Spenolobene-5,16-dione
O OH
O
OAc
H
O
H
O
OH
AcO
O
O
OH
N
O
H
Ph
Ph
Ph
Paclitaxel or Taxol
Tigliane and ingenane diterpenoids
Verrucosane diterpenoids
O
OH
O
H
O
H
O
H
O
H
OH
4β, 9α, 12β, 13α, 16α, 20β-Hexa-hydroxy-1,6-tigliadien-3-one
OH
OH
OH
2β, 9α, 13β-Verrucosanetriol
Xenicane and xeniaphyllane diterpenoids
O
OAc
AcO
AcO
OAc
Xenicin
Botanical sources
Diterpenes are found in nature, mainly in plants, but also in other
natural sources, e.g. micro-organisms and insects. The following table
presents just a few of these sources, and their major diterpenoidal
components.
346
CH6 NATURAL PRODUCT CHEMISTRY