countries. Therefore, there has been a pressing need for a chemistry text
covering the fundamentals of general, organic and natural product chemistry
written at a correct level for the Pharmacy undergraduates. Physical
(Preformulation) and Analytical Chemistry (Pharmaceutical Analysis) are
generally taught separately at year 2 and year 3 levels of any modern
MPharm course, and there are a number of excellent and up-to-date texts
available in these areas.
During our teaching careers, we have always struggled to find an
appropriate book that can offer general, organic and natural product
chemistry at the right level for Pharmacy undergraduate students, and
address the current changes in pharmacy curricula all over the world, at
least in the UK. We have always ended up recommending several books,
and also writing notes for the students. Therefore, we have decided to
address this issue by compiling a chemistry book for Pharmacy students,
which will cover general, organic and natural product chemistry in relation
to drug molecules. Thus, the aims of our book are to provide the fundamental knowledge and overview of all core topics related to general, organic
and natural product chemistry currently taught in Pharmacy undergraduate
courses in the UK, USA and various other developed countries, relate these
topics to the better understanding of drug molecules and their development
and meet the demand of the recent changes in pharmacy curricula. This
book attempts to condense the essentials of general, organic and natural
product chemistry into a manageable, affordable and student-friendly text,
by concentrating purely on the basics of various topics without going into
exhaustive detail or repetitive examples.
In Pharmacy undergraduate courses, especially in the UK, we get students
of heterogeneous educational backgrounds; while some of them have very
good chemistry background, the others have bare minimum or not at all.
From our experience in teaching Pharmacy undergraduate students, we have
been able to identify the appropriate level that is required for all these
students to learn properly. While we recognise that learning styles and levels
vary from student to student, we can still try to strike the balance in terms of
the level and standard at a point, which is not too difficult or not too easy for
any students, but will certainly be student friendly. Bearing this in mind, the
contents of this book are organized and dealt with in a way that they are
suitable for year 1 and year 2 levels of the pharmacy curriculum. While the
theoretical aspects of various topics are covered adequately, much focus has
been given to the applications of these theories in relation to drug molecules
and their discovery and developments. Chapter 1 provides an overview of
some general aspects of chemistry and their importance in modern life, with
particular emphasis on medicinal applications, and brief discussions of
various physical characteristics of drug molecules, e.g. pH, polarity and
solubility. While Chapter 2 deals with the fundamentals of atomic structure
x
PREFACE
covering the fundamentals of general, organic and natural product chemistry
written at a correct level for the Pharmacy undergraduates. Physical
(Preformulation) and Analytical Chemistry (Pharmaceutical Analysis) are
generally taught separately at year 2 and year 3 levels of any modern
MPharm course, and there are a number of excellent and up-to-date texts
available in these areas.
During our teaching careers, we have always struggled to find an
appropriate book that can offer general, organic and natural product
chemistry at the right level for Pharmacy undergraduate students, and
address the current changes in pharmacy curricula all over the world, at
least in the UK. We have always ended up recommending several books,
and also writing notes for the students. Therefore, we have decided to
address this issue by compiling a chemistry book for Pharmacy students,
which will cover general, organic and natural product chemistry in relation
to drug molecules. Thus, the aims of our book are to provide the fundamental knowledge and overview of all core topics related to general, organic
and natural product chemistry currently taught in Pharmacy undergraduate
courses in the UK, USA and various other developed countries, relate these
topics to the better understanding of drug molecules and their development
and meet the demand of the recent changes in pharmacy curricula. This
book attempts to condense the essentials of general, organic and natural
product chemistry into a manageable, affordable and student-friendly text,
by concentrating purely on the basics of various topics without going into
exhaustive detail or repetitive examples.
In Pharmacy undergraduate courses, especially in the UK, we get students
of heterogeneous educational backgrounds; while some of them have very
good chemistry background, the others have bare minimum or not at all.
From our experience in teaching Pharmacy undergraduate students, we have
been able to identify the appropriate level that is required for all these
students to learn properly. While we recognise that learning styles and levels
vary from student to student, we can still try to strike the balance in terms of
the level and standard at a point, which is not too difficult or not too easy for
any students, but will certainly be student friendly. Bearing this in mind, the
contents of this book are organized and dealt with in a way that they are
suitable for year 1 and year 2 levels of the pharmacy curriculum. While the
theoretical aspects of various topics are covered adequately, much focus has
been given to the applications of these theories in relation to drug molecules
and their discovery and developments. Chapter 1 provides an overview of
some general aspects of chemistry and their importance in modern life, with
particular emphasis on medicinal applications, and brief discussions of
various physical characteristics of drug molecules, e.g. pH, polarity and
solubility. While Chapter 2 deals with the fundamentals of atomic structure
x
PREFACE