Boffetta P, Hashibe M (2006) Alcohol and cancer. Lancet Oncol 7:149–156
Bolt HM, Their R (2006) Relevance of the deletion polymorphisms of the glutathione
S-Transferases GSTT1 and GSTM1 in pharmacology and toxicology. Curr Drug Metab
7:613–628
Brennan P, Boffetta P (2004) Mechanistic considerations in the molecular epidemiology of head
and neck cancer. IARC Sci Publ 157:393–414
Cai S, Li Y, Ding Y et al (2014) Alcohol drinking and the risk of colorectal cancer death: a metaanalysis. Eur J Cancer Prev 23:532–539
Caporaso NE, Lerman C, Audrain J et al (2001) Nicotine metabolism and CYP2D6 phenotype in
smokers. Cancer Epidemiol Biomark Prev 10:261–263
Cascorbi I, Brockmoeller J, Roots I (1996) A C4887A polymorphism in exon 7 of human CYP1A1:
population frequency, mutation linkages, and impact on lung cancer susceptibility. Cancer Res
56:4965–4969
Chang HW, Ling GS, Wei WI et al (2004) Smoking and drinking can induce p15 methylation in the
upper aerodigestive tract of healthy individuals and patients with head and neck squamous cell
carcinoma. Cancer 101:125–132
Choi SY, Kahyo H (1991) Effect of cigarette smoking and alcohol consumption in the aetiology of
cancer of the oral cavity, pharynx and larynx. Int J Epidemiol 20:878–885
Coggan M, Whitbread L, Whittington A et al (1998) Structure and organization of the human thetaclass glutathione S-transferase and D-dopachrome tautomerase gene complex. Biochem J
334:617–623
Daigo S, Takahashi Y, Fujieda M et al (2002) A novel mutant allele of the CYP2A6 gene
(CYP2A6*11) found in a cancer patient who showed poor metabolic phenotype towards
tegafur. Pharmacogenetics 12:299–306
Dandara C, Sayi J, Masimirembwa CM et al (2002) Genetic polymorphism of cytochrome P450
1A1 (CYP1A1) and glutathione transferases (M1, T1 and P1) among Africans. Clin Chem Lab
Med 40:952–957
Danko IM, Chaschin NA (2005) Association of CYP2E1 gene polymorphism with predisposition to
cancer development. Exp Oncol 27:248–256
Doll R, Hill AB (1950) Smoking and carcinoma of the lung; preliminary report. Br Med J
2:739–748
Doll R, Forman D, La Vecchia C et al (1999) Alcoholic beverages and cancers of the digestive tract
and larynx. In: Health issues related to alcohol consumption, 2nd edn. Blackwell, Oxford, pp
351–393
Evans WE, Relling MV (1999) Pharmacogenomics: translating functional genomics into rational
therapeutics. Science 286:487–491
Ferrari P, Jenab M, Norat T et al (2007) Lifetime and baseline alcohol intake and risk of colon and
rectal cancers in the European prospective investigation into cancer and nutrition (EPIC). Int J
Cancer 121:2065–2072
Franceschi S, Levi F, Dal Maso L et al (2000) Cessation of alcohol drinking and risk of cancer of the
oral cavity and pharynx. Int J Cancer 85:787–790
Freudenheim JL, Ritz J, Smith-Warner SA et al (2005) Alcohol consumption and risk of lung
cancer: a pooled analysis of cohort studies. Am J Clin Nutr 82:657–667
García-Closas M, Malats N, Silverman D et al (2005) NAT2 slow acetylation, GSTM1 null
genotype, and risk of bladder cancer: results from the Spanish bladder Cancer study and
meta-analyses. Lancet 366:649–659
Garte S, Gaspari L, Alexandrie AK et al (2001) Metabolic gene polymorphism frequencies in
control populations. Cancer Epidemiol Biomark Prev 10:1239–1248
Guengerich FP, Kim DH, Iwasaki M et al (1991) Role of human cytochrome P-450 IIE1 in the
oxidation of many low molecular weight cancer suspects. Chem Res Toxicol 4:168–179
Hamajima N, Hirose K, Tajima K et al (2002) Alcohol, tobacco and breast cancer--collaborative
reanalysis of individual data from 53 epidemiological studies, including 58,515 women with
breast cancer and 95,067 women without the disease. Br J Cancer 87:1234–1245
10 Interactions of Environmental Risk Factors and Genetic Variations: Association. . .
229
Bolt HM, Their R (2006) Relevance of the deletion polymorphisms of the glutathione
S-Transferases GSTT1 and GSTM1 in pharmacology and toxicology. Curr Drug Metab
7:613–628
Brennan P, Boffetta P (2004) Mechanistic considerations in the molecular epidemiology of head
and neck cancer. IARC Sci Publ 157:393–414
Cai S, Li Y, Ding Y et al (2014) Alcohol drinking and the risk of colorectal cancer death: a metaanalysis. Eur J Cancer Prev 23:532–539
Caporaso NE, Lerman C, Audrain J et al (2001) Nicotine metabolism and CYP2D6 phenotype in
smokers. Cancer Epidemiol Biomark Prev 10:261–263
Cascorbi I, Brockmoeller J, Roots I (1996) A C4887A polymorphism in exon 7 of human CYP1A1:
population frequency, mutation linkages, and impact on lung cancer susceptibility. Cancer Res
56:4965–4969
Chang HW, Ling GS, Wei WI et al (2004) Smoking and drinking can induce p15 methylation in the
upper aerodigestive tract of healthy individuals and patients with head and neck squamous cell
carcinoma. Cancer 101:125–132
Choi SY, Kahyo H (1991) Effect of cigarette smoking and alcohol consumption in the aetiology of
cancer of the oral cavity, pharynx and larynx. Int J Epidemiol 20:878–885
Coggan M, Whitbread L, Whittington A et al (1998) Structure and organization of the human thetaclass glutathione S-transferase and D-dopachrome tautomerase gene complex. Biochem J
334:617–623
Daigo S, Takahashi Y, Fujieda M et al (2002) A novel mutant allele of the CYP2A6 gene
(CYP2A6*11) found in a cancer patient who showed poor metabolic phenotype towards
tegafur. Pharmacogenetics 12:299–306
Dandara C, Sayi J, Masimirembwa CM et al (2002) Genetic polymorphism of cytochrome P450
1A1 (CYP1A1) and glutathione transferases (M1, T1 and P1) among Africans. Clin Chem Lab
Med 40:952–957
Danko IM, Chaschin NA (2005) Association of CYP2E1 gene polymorphism with predisposition to
cancer development. Exp Oncol 27:248–256
Doll R, Hill AB (1950) Smoking and carcinoma of the lung; preliminary report. Br Med J
2:739–748
Doll R, Forman D, La Vecchia C et al (1999) Alcoholic beverages and cancers of the digestive tract
and larynx. In: Health issues related to alcohol consumption, 2nd edn. Blackwell, Oxford, pp
351–393
Evans WE, Relling MV (1999) Pharmacogenomics: translating functional genomics into rational
therapeutics. Science 286:487–491
Ferrari P, Jenab M, Norat T et al (2007) Lifetime and baseline alcohol intake and risk of colon and
rectal cancers in the European prospective investigation into cancer and nutrition (EPIC). Int J
Cancer 121:2065–2072
Franceschi S, Levi F, Dal Maso L et al (2000) Cessation of alcohol drinking and risk of cancer of the
oral cavity and pharynx. Int J Cancer 85:787–790
Freudenheim JL, Ritz J, Smith-Warner SA et al (2005) Alcohol consumption and risk of lung
cancer: a pooled analysis of cohort studies. Am J Clin Nutr 82:657–667
García-Closas M, Malats N, Silverman D et al (2005) NAT2 slow acetylation, GSTM1 null
genotype, and risk of bladder cancer: results from the Spanish bladder Cancer study and
meta-analyses. Lancet 366:649–659
Garte S, Gaspari L, Alexandrie AK et al (2001) Metabolic gene polymorphism frequencies in
control populations. Cancer Epidemiol Biomark Prev 10:1239–1248
Guengerich FP, Kim DH, Iwasaki M et al (1991) Role of human cytochrome P-450 IIE1 in the
oxidation of many low molecular weight cancer suspects. Chem Res Toxicol 4:168–179
Hamajima N, Hirose K, Tajima K et al (2002) Alcohol, tobacco and breast cancer--collaborative
reanalysis of individual data from 53 epidemiological studies, including 58,515 women with
breast cancer and 95,067 women without the disease. Br J Cancer 87:1234–1245
10 Interactions of Environmental Risk Factors and Genetic Variations: Association. . .
229