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Infectious Diseases, 71(6), 462–466.
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dermatophytosis, onychomycosis, and tinea versicolor. Infectious Disease Clinics of North
America, 17, 87–112.
Yamada, T., Makimura, K., Satoh, K., Umeda, Y., Ishihara, Y., & Abe, S. (2009). Agrobacterium
tumefaciens -mediated transformation of the dermatophyte, Trichophyton mentagrophytes: An
efficient tool for gene transfer. Medical Mycology, 47, 485–494.
Yamada, T., Makimura, K., et al. (2006). Isolation, characterization, and disruption of dnr1, the are
a/nit-2-like nitrogen regulatory gene of the zoophilic dermatophyte, Microsporum canis. Medical Mycology May, 44, 243–252.
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Favre, B., & Ryder, N. S. (1996). Characterization of squalene epoxidase activity from the
dermatophyte Trichophyton rubrum and its inhibition by terbinafine and other antimycotic
agents. Antimicrobial Agents and Chemotherapy, 40, 443–447.
Fukushima, M. (2016). The history and forecast of “Project for Translational and Clinical Research
Core Centers” The ARO establishment for driving innovation mechanism, and aiming for
disruptive innovation. Rinsho Hyoka (Clinical Evaluation), 44(3), 417–428.
Hunter, P. (2013). Research funding is not enough. EMBO Reports, 14(2), 140–142.
JST. (2012). https://www.jst.go.jp/tt/EN/promoTechTransInnovation.pdf.2020.6
Kemna, M. E., & Elewski, B. E. (1996). A U.S. epidemiologic survey of superficial fungal diseases.
Journal of the American Academy of Dermatology, 35, 539–542.
Leyden, J. (1998). Pharmacokinetics and pharmacology of terbinafine and itraconazole. Journal of
the American Academy of Dermatology, 38(S), 42–47.
Morrison, R. P. (2010). Lost in translation—Basic science in the era of translational research.
Infection and Immunity, 78, 563–566.
Mukherjee, P. K., Leidich, S. D., Isham, N., Leitner, I., Ryder, N. S., & Ghannoum, M. A. (2003).
Clinical Trichophyton rubrum strain exhibiting primary resistance to terbinafine. Antimicrobial
Agents and Chemotherapy, 47, 82–86.
Ohno, T., Nagai, Y., & Fukushima, M. (2010). Progression and future of translational research in
Japan. Folia Pharmacologica Japonica, 135, 190–193.
Onozaki, M., Makimur, K., et al. (2009). Rapid identification of Prototheca zopfii by nested
polymerase chain reaction based on the nuclear small subunit ribosomal DNA. Journal of
Dermatological Science, 54(1), 56–59.
Osborne, C. S., Leitner, I., Favre, B., & Ryder, N. S. (2005). Amino acid substitution in
Trichophyton rubrum squalene epoxidase associated with resistance to terbinafine. Antimicrobial Agents and Chemotherapy, 49, 2840–2844.
Pisano, G. P. (2006). Science business: The promise, the reality, and the future of biotech. Boston:
Harvard Business School Press.
Sutton, L., et al. (2019). Facilitating translational team science: The project leader model. Journal of
Clinical and Translational Science, 3, 140–146. https://doi.org/10.1017/cts.2019.398
Suzuki, S., Fujitani, K., et al. (2018a). Discovery of terbinafine low susceptibility Trichophyton
rubrum strain in Japan. Biocontrol Science, 23(3), 151–154.
Suzuki, S., Fujitani, K., et al. (2018b). Molecular epidemiological analysis of the spreading
conditions of Trichophyton in the long-term care facilities in Japan. Japanese Journal of
Infectious Diseases, 71(6), 462–466.
Tanaka, N. (2010). From basics to clinical: Past and present of translational research. Folia
Pharmacologica Japonica, 136, 290–293.
The Japan times. “The crisis in Japan’s scientific research output” Aug 31, 2017
Valenti, A., et al. (2016). White paper, translational science and its effects on organizational
structure and program management. https://www.pmi.org/-/media/pmi/documents/public/pdf/
research/translational-science-organizational-structure.pdf?v=7a43b154-6a41-4336-9d364c373aa52a25.2020.6
Vander Straten, M. R., Hossain, M. A., & Ghannoum, M. A. (2003). Cutaneous infections
dermatophytosis, onychomycosis, and tinea versicolor. Infectious Disease Clinics of North
America, 17, 87–112.
Yamada, T., Makimura, K., Satoh, K., Umeda, Y., Ishihara, Y., & Abe, S. (2009). Agrobacterium
tumefaciens -mediated transformation of the dermatophyte, Trichophyton mentagrophytes: An
efficient tool for gene transfer. Medical Mycology, 47, 485–494.
Yamada, T., Makimura, K., et al. (2006). Isolation, characterization, and disruption of dnr1, the are
a/nit-2-like nitrogen regulatory gene of the zoophilic dermatophyte, Microsporum canis. Medical Mycology May, 44, 243–252.
152
K. Fujitani et al.