Table 10.2 Commonly used constitutive and inducible/repressible fungal promoters
Origin
Gene
Gene product
Inducer/repressor
a
References
Aspergillus sp. gpdA
Glyceraldehyde-3-phosphate
dehydrogenase
À/À
Archer et al. (1990)
tef1
Transcription elongation factor 1a À/À
Kitamoto et al. (1998)
pki1
Pyruvate kinase
À/À
de Graaff and Visser
(1988)
sodM
Manganese superoxide-dismutase À/À
Ishida et al. (2004)
glaA
Glucoamylase A
Starch, glucose/xylose Boel et al. (1984)
amyA/
amyB
a-amylase
Starch, maltose/
glucose
Gomi et al. (2000)
alcA
Alcohol dehydrogenase I
Ethanol/glucose
Waring et al. (1989)
niiA
Nitrite reductase
Nitrate/ammonium
Muller et al. (2002)
thiA
Thiamine thiazole synthase
–/thiamine
Shoji et al. (2005)
sorA/sorB Sugar transporter/sorbitol
dehydrogenase
Sorbitol/Oda et al. (2016)
Trichoderma
reesei
gpdA
Glyceraldehyde-3-phosphate
dehydrogenase
À/À
Li et al. (2012)
tef1
Transcription elongation factor 1a À/À
Nakari-Seta ¨la ¨ and Penttila ¨
(1995)
pki1
Pyruvate kinase
À/À
Kurzatkowski et al. (1996)
eno1
Enolase
À/À
Li et al. (2012)
cDNA1
Hypothetical protein
(Trire2:110879)
À/À
Nakari-Seta ¨la ¨ and Penttila ¨
(1995)
hex1
Woronin body protein
À/À
Bergquist et al. (2004)
cel6a
Cellobiohydrolase, CBH II
Cellulose, lactose/
glucose
Zeilinger et al. (1998)
cel7a
Cellobiohydrolase, CBH I
Cellulose, lactose/
glucose
Ilme ´n et al. (1998)
cel5a
Endoglucanase, EG2
Cellulose, lactose/
glucose
Miyauchi et al. (2013)
cel12a
Endoglucanase, EG3
Cellulose, lactose/
glucose
Rahman et al. (2009)
xyn1
Xylanase I
Xylan/glucose
Zeilinger et al. (1996)
Penicillium sp. pgkA
3-phosphoglycerate kinase
À/À
Hoskins and Roberts
(1994)
gdhA
NADP-dependent glutamate
dehydrogenase
À/À
Dı ´ez et al. (1999)
paf
Antifungal protein
À/À
Marx et al. (1995)
xylP
Endoxylanase
Xylose/glucose
Zadra et al. (2000)
phoA
Acid phosphatase
–/phosphate
Haas et al. (1992)
pbcC
Isopenicillin N synthase
Lactose, alkaline
pH/n.d.
Barredo et al. (1989)
gla1
Glucoamylase
Glucose/xylose
Bulakhov et al. (2017)
Neurospora
crassa
tub
Beta-tubulin
À/À
Nakano et al. (1993)
bli-3
Blue light-inducible gene
Blue light/darkness
Eberle and Russo (1994)
qa-2
Catabolic 3-dehydroquinase
High/low quinic acid Giles et al. (1985)
tcu-1
Copper transporter
Copper depletion/
availability
Lamb et al. (2013)
vvd
Blue light receptor
Light/darkness
Hurley et al. (2012)
ccg-1
Clock-controlled gene 1
Light/glucose
McNally and Free (1988)
gla1
Glucoamylase
Starch, maltose/
glucose
Stone et al. (1993)
a
Constitutive promoters are labelled (À/À). For regulated promoters, the inducing/repressing compounds or conditions are
indicated
10 Filamentous Fungi as Hosts for Heterologous Production of Proteins and Secondary. . .
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