Seong K-Y, Tetko IV, Urban M, Waalwijk C, Ward
TJ, Yao J, Birren BW, Kistler HC (2007) The Fusarium graminearum genome reveals a link between
localized polymorphism and pathogen specialization. Science 317:1400–1402. https://doi.org/
10.1126/science.1143708
de Wit PJGM, van der Burgt A, O ¨ kmen B, Stergiopoulos
I, Abd-Elsalam KA, Aerts AL, Bahkali AH, Beenen
HG, Chettri P, Cox MP, Datema E, de Vries RP,
Dhillon B, Ganley AR, Griffiths SA, Guo Y, Hamelin RC, Henrissat B, Kabir MS, Jashni MK, Kema G,
Klaubauf S, Lapidus A, Levasseur A, Lindquist E,
Mehrabi R, Ohm RA, Owen TJ, Salamov A,
Schwelm A, Schijlen E, Sun H, van den Burg HA,
van Ham RCHJ, Zhang S, Goodwin SB, Grigoriev
IV, Collemare J, Bradshaw RE (2012) The genomes
of the fungal plant pathogens Cladosporium fulvum and Dothistroma septosporum reveal adaptation to different hosts and lifestyles but also
signatures of common ancestry. PLoS Genet 8:
e1003088.
https://doi.org/10.1371/journal.
pgen.1003088
Downs JR, Clearfield M, Weis S, Whitney E, Shapiro
DR, Beere PA, Langendorfer A, Stein EA, Kruyer
W, Gotto AM Jr, for the AFCAPS/TexCAPS
Research Group for the AR (1998) Primary prevention of acute coronary events with lovastatin in
men and women with average cholesterol levels.
JAMA
279:1615.
https://doi.org/10.1001/
jama.279.20.1615
Druzhinina IS, Seidl-Seiboth V, Herrera-Estrella A,
Horwitz BA, Kenerley CM, Monte E, Mukherjee
PK, Zeilinger S, Grigoriev IV, Kubicek CP (2011)
Trichoderma: the genomics of opportunistic success. Nat Rev Microbiol 9:749–759. https://doi.org/
10.1038/nrmicro2637
Eid J, Fehr A, Gray J, Luong K, Lyle J, Otto G, Peluso P,
Rank D, Baybayan P, Bettman B, Bibillo A, Bjornson K, Chaudhuri B, Christians F, Cicero R, Clark
S, Dalal R, Dewinter A, Dixon J, Foquet M, Gaertner A, Hardenbol P, Heiner C, Hester K, Holden D,
Kearns G, Kong X, Kuse R, Lacroix Y, Lin S, Lundquist P, Ma C, Marks P, Maxham M, Murphy D,
Park I, Pham T, Phillips M, Roy J, Sebra R, Shen G,
Sorenson J, Tomaney A, Travers K, Trulson M,
Vieceli J, Wegener J, Wu D, Yang A, Zaccarin D,
Zhao P, Zhong F, Korlach J, Turner S (2009) Realtime DNA sequencing from single polymerase
molecules. Science 323:133–138. https://doi.org/
10.1126/science.1162986
Finn RD, Coggill P, Eberhardt RY, Eddy SR, Mistry J,
Mitchell AL, Potter SC, Punta M, Qureshi M,
Sangrador-Vegas A, Salazar GA, Tate J, Bateman
A (2016) The Pfam protein families database:
towards a more sustainable future. Nucleic Acids
Res 44:D279–D285. https://doi.org/10.1093/nar/
gkv1344
Fleischmann R, Adams M, White O, Clayton R, Kirkness E, Kerlavage A, Bult C, Tomb J, Dougherty B,
Merrick J, Mewes HW, Murakami Y, Philippsen P,
Tettelin H, Oliver SG et al (1995) Whole-genome
random sequencing and assembly of Haemophilus
influenzae Rd. Science 269:496–512. https://doi.
org/10.1126/science.7542800
Floudas D, Binder M, Riley R, Barry K, Blanchette RA,
Henrissat B, Martı ´nez AT, Otillar R, Spatafora JW,
Yadav JS, Aerts A, Benoit I, Boyd A, Carlson A,
Copeland A, Coutinho PM, de Vries RP, Ferreira P,
Findley K, Foster B, Gaskell J, Glotzer D, Go ´recki
P, Heitman J, Hesse C, Hori C, Igarashi K, Jurgens
JA, Kallen N, Kersten P, Kohler A, Ku ¨es U, Kumar
TKA, Kuo A, LaButti K, Larrondo LF, Lindquist E,
Ling A, Lombard V, Lucas S, Lundell T, Martin R,
McLaughlin DJ, Morgenstern I, Morin E, Murat C,
Nagy LG, Nolan M, Ohm RA, Patyshakuliyeva A,
Rokas A, Ruiz-Duen ˜as FJ, Sabat G, Salamov A,
Samejima M, Schmutz J, Slot JC, St John F, Stenlid
J, Sun H, Sun S, Syed K, Tsang A, Wiebenga A,
Young D, Pisabarro A, Eastwood DC, Martin F,
Cullen D, Grigoriev IV, Hibbett DS (2012) The
Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes. Science 336:1715–1719. https://doi.org/10.1126/
science.1221748
Galagan JE, Calvo SE, Borkovich KA, Selker EU, Read
ND, Jaffe D, FitzHugh W, Ma L-J, Smirnov S,
Purcell S, Rehman B, Elkins T, Engels R, Wang S,
Nielsen CB, Butler J, Endrizzi M, Qui D, Ianakiev
P, Bell-Pedersen D, Nelson MA, WernerWashburne M, Selitrennikoff CP, Kinsey JA,
Braun EL, Zelter A, Schulte U, Kothe GO, Jedd G,
Mewes W, Staben C, Marcotte E, Greenberg D, Roy
A, Foley K, Naylor J, Stange-Thomann N, Barrett
R, Gnerre S, Kamal M, Kamvysselis M, Mauceli E,
Bielke C, Rudd S, Frishman D, Krystofova S, Rasmussen C, Metzenberg RL, Perkins DD, Kroken S,
Cogoni C, Macino G, Catcheside D, Li W, Pratt RJ,
Osmani SA, DeSouza CPC, Glass L, Orbach MJ,
Berglund JA, Voelker R, Yarden O, Plamann M,
Seiler S, Dunlap J, Radford A, Aramayo R, Natvig
DO, Alex LA, Mannhaupt G, Ebbole DJ, Freitag M,
Paulsen I, Sachs MS, Lander ES, Nusbaum C, Birren B (2003) The genome sequence of the filamentous fungus Neurospora crassa. Nature 422:859–
868. https://doi.org/10.1038/nature01554
Galagan JE, Calvo SE, Cuomo C, Ma L-J, Wortman JR,
Batzoglou S, Lee S-I, Bas ¸tu ¨rkmen M, Spevak CC,
Clutterbuck J, Kapitonov V, Jurka J, Scazzocchio
C, Farman M, Butler J, Purcell S, Harris S, Braus
GH, Draht O, Busch S, D’Enfert C, Bouchier C,
Goldman GH, Bell-Pedersen D, Griffiths-Jones S,
Doonan JH, Yu J, Vienken K, Pain A, Freitag M,
Selker EU, Archer DB, Pen ˜alva MA ´ , Oakley BR,
Momany M, Tanaka T, Kumagai T, Asai K,
Machida M, Nierman WC, Denning DW, Caddick
M, Hynes M, Paoletti M, Fischer R, Miller B, Dyer
P, Sachs MS, Osmani SA, Birren BW (2005)
Sequencing of Aspergillus nidulans and compara218
R. A. Ohm
TJ, Yao J, Birren BW, Kistler HC (2007) The Fusarium graminearum genome reveals a link between
localized polymorphism and pathogen specialization. Science 317:1400–1402. https://doi.org/
10.1126/science.1143708
de Wit PJGM, van der Burgt A, O ¨ kmen B, Stergiopoulos
I, Abd-Elsalam KA, Aerts AL, Bahkali AH, Beenen
HG, Chettri P, Cox MP, Datema E, de Vries RP,
Dhillon B, Ganley AR, Griffiths SA, Guo Y, Hamelin RC, Henrissat B, Kabir MS, Jashni MK, Kema G,
Klaubauf S, Lapidus A, Levasseur A, Lindquist E,
Mehrabi R, Ohm RA, Owen TJ, Salamov A,
Schwelm A, Schijlen E, Sun H, van den Burg HA,
van Ham RCHJ, Zhang S, Goodwin SB, Grigoriev
IV, Collemare J, Bradshaw RE (2012) The genomes
of the fungal plant pathogens Cladosporium fulvum and Dothistroma septosporum reveal adaptation to different hosts and lifestyles but also
signatures of common ancestry. PLoS Genet 8:
e1003088.
https://doi.org/10.1371/journal.
pgen.1003088
Downs JR, Clearfield M, Weis S, Whitney E, Shapiro
DR, Beere PA, Langendorfer A, Stein EA, Kruyer
W, Gotto AM Jr, for the AFCAPS/TexCAPS
Research Group for the AR (1998) Primary prevention of acute coronary events with lovastatin in
men and women with average cholesterol levels.
JAMA
279:1615.
https://doi.org/10.1001/
jama.279.20.1615
Druzhinina IS, Seidl-Seiboth V, Herrera-Estrella A,
Horwitz BA, Kenerley CM, Monte E, Mukherjee
PK, Zeilinger S, Grigoriev IV, Kubicek CP (2011)
Trichoderma: the genomics of opportunistic success. Nat Rev Microbiol 9:749–759. https://doi.org/
10.1038/nrmicro2637
Eid J, Fehr A, Gray J, Luong K, Lyle J, Otto G, Peluso P,
Rank D, Baybayan P, Bettman B, Bibillo A, Bjornson K, Chaudhuri B, Christians F, Cicero R, Clark
S, Dalal R, Dewinter A, Dixon J, Foquet M, Gaertner A, Hardenbol P, Heiner C, Hester K, Holden D,
Kearns G, Kong X, Kuse R, Lacroix Y, Lin S, Lundquist P, Ma C, Marks P, Maxham M, Murphy D,
Park I, Pham T, Phillips M, Roy J, Sebra R, Shen G,
Sorenson J, Tomaney A, Travers K, Trulson M,
Vieceli J, Wegener J, Wu D, Yang A, Zaccarin D,
Zhao P, Zhong F, Korlach J, Turner S (2009) Realtime DNA sequencing from single polymerase
molecules. Science 323:133–138. https://doi.org/
10.1126/science.1162986
Finn RD, Coggill P, Eberhardt RY, Eddy SR, Mistry J,
Mitchell AL, Potter SC, Punta M, Qureshi M,
Sangrador-Vegas A, Salazar GA, Tate J, Bateman
A (2016) The Pfam protein families database:
towards a more sustainable future. Nucleic Acids
Res 44:D279–D285. https://doi.org/10.1093/nar/
gkv1344
Fleischmann R, Adams M, White O, Clayton R, Kirkness E, Kerlavage A, Bult C, Tomb J, Dougherty B,
Merrick J, Mewes HW, Murakami Y, Philippsen P,
Tettelin H, Oliver SG et al (1995) Whole-genome
random sequencing and assembly of Haemophilus
influenzae Rd. Science 269:496–512. https://doi.
org/10.1126/science.7542800
Floudas D, Binder M, Riley R, Barry K, Blanchette RA,
Henrissat B, Martı ´nez AT, Otillar R, Spatafora JW,
Yadav JS, Aerts A, Benoit I, Boyd A, Carlson A,
Copeland A, Coutinho PM, de Vries RP, Ferreira P,
Findley K, Foster B, Gaskell J, Glotzer D, Go ´recki
P, Heitman J, Hesse C, Hori C, Igarashi K, Jurgens
JA, Kallen N, Kersten P, Kohler A, Ku ¨es U, Kumar
TKA, Kuo A, LaButti K, Larrondo LF, Lindquist E,
Ling A, Lombard V, Lucas S, Lundell T, Martin R,
McLaughlin DJ, Morgenstern I, Morin E, Murat C,
Nagy LG, Nolan M, Ohm RA, Patyshakuliyeva A,
Rokas A, Ruiz-Duen ˜as FJ, Sabat G, Salamov A,
Samejima M, Schmutz J, Slot JC, St John F, Stenlid
J, Sun H, Sun S, Syed K, Tsang A, Wiebenga A,
Young D, Pisabarro A, Eastwood DC, Martin F,
Cullen D, Grigoriev IV, Hibbett DS (2012) The
Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes. Science 336:1715–1719. https://doi.org/10.1126/
science.1221748
Galagan JE, Calvo SE, Borkovich KA, Selker EU, Read
ND, Jaffe D, FitzHugh W, Ma L-J, Smirnov S,
Purcell S, Rehman B, Elkins T, Engels R, Wang S,
Nielsen CB, Butler J, Endrizzi M, Qui D, Ianakiev
P, Bell-Pedersen D, Nelson MA, WernerWashburne M, Selitrennikoff CP, Kinsey JA,
Braun EL, Zelter A, Schulte U, Kothe GO, Jedd G,
Mewes W, Staben C, Marcotte E, Greenberg D, Roy
A, Foley K, Naylor J, Stange-Thomann N, Barrett
R, Gnerre S, Kamal M, Kamvysselis M, Mauceli E,
Bielke C, Rudd S, Frishman D, Krystofova S, Rasmussen C, Metzenberg RL, Perkins DD, Kroken S,
Cogoni C, Macino G, Catcheside D, Li W, Pratt RJ,
Osmani SA, DeSouza CPC, Glass L, Orbach MJ,
Berglund JA, Voelker R, Yarden O, Plamann M,
Seiler S, Dunlap J, Radford A, Aramayo R, Natvig
DO, Alex LA, Mannhaupt G, Ebbole DJ, Freitag M,
Paulsen I, Sachs MS, Lander ES, Nusbaum C, Birren B (2003) The genome sequence of the filamentous fungus Neurospora crassa. Nature 422:859–
868. https://doi.org/10.1038/nature01554
Galagan JE, Calvo SE, Cuomo C, Ma L-J, Wortman JR,
Batzoglou S, Lee S-I, Bas ¸tu ¨rkmen M, Spevak CC,
Clutterbuck J, Kapitonov V, Jurka J, Scazzocchio
C, Farman M, Butler J, Purcell S, Harris S, Braus
GH, Draht O, Busch S, D’Enfert C, Bouchier C,
Goldman GH, Bell-Pedersen D, Griffiths-Jones S,
Doonan JH, Yu J, Vienken K, Pain A, Freitag M,
Selker EU, Archer DB, Pen ˜alva MA ´ , Oakley BR,
Momany M, Tanaka T, Kumagai T, Asai K,
Machida M, Nierman WC, Denning DW, Caddick
M, Hynes M, Paoletti M, Fischer R, Miller B, Dyer
P, Sachs MS, Osmani SA, Birren BW (2005)
Sequencing of Aspergillus nidulans and compara218
R. A. Ohm