151
R
O
O
HP
20 mol% AgSbF 6
3.0 equiv K 2 S 2 O 8
DMSO, Ar, 35 °C
R
R
1
R
2
+
O
O
O
P
O
R
1
R
2
O
O
P
O
OEt
EtO
70%
O
O
P
O
OMe
MeO
61%
O
O
P
O
OBn
BnO
53%
O
O
P
O
OEt
EtO
64%
O
O
P
O
OEt
EtO
32%
Cl
O
O
P
O
OEt
EtO
32%
MeO
O
PR 1 R 2 H
O
PR 1 R
2
R
O
O
AgNO 3
K 2 S 2 O 8
R
O
O
R
O
O
radical
annulation
radical coupling
R
O
O
P
O
R
1
R 2
AgNO 3
K 2 S 2 O 8
Scheme 4.73 Oxidative C-P bond formation through cascade process
4 Oxidative Radical Couplings