420
P. M. Vassiliev et al.
Table 12.19  Results of predicting the hypoglycemic activity of the main components of Gymnema
sylvestre extract and of their mixtures
Substance, mixture
Estimate
a
Fb
b
Gymnemic acid I (XV)
A
0.60085
Gymnemic acid II (XVI)
A
0.68467
Gymnemic acid III (XVII)
A
0.83221
Gymnemic acid IV (XVIII)
A
0.60085
Gymnemoside A (XIX)
A
0.60085
Gymnemoside B (XX)
N
0.50802
Conduritol B (XXI)
N
0.99996
Mixture 1– (XV-XXI) 1:1:1:1:1:1:1
A
0.91614
Mixture 2– (XV-XIX) 1:1:1:1:1
A
0.91614
Mixture 3– (XV-XIX) 1:1:2:1:1
A
0.83010
Mixture 4– (XV-XIX) 1:1:3:1:1
A
0.83010
Mixture 5– (XVI, XVII) 1:2
A
0.81400
Mixture 5– (XVI, XVII, XXI) 1:2:3
A
0.81400
a
Prediction with the normal strategy, nearest neighbor method
b
Membership function
Fig. 12.7  The main components of Gymnema sylvestre extract