332
A. Zakharov and A. Lagunin
Database
Definition
DRAR-CPI
Prediction of Drug Repositioning and Adverse Reaction via Chemical-Protein
Interactome: http://cpi.bio-x.cn/drar/
Drugs@FDA Information about the US FDA approved drug products: http://www.fda.gov/
Drugs/InformationOnDrugs/ucm135821.htm
DSSTox
Distributed Structure-Searchable Toxicity Database Network. Distributed toxicity databases, which is focused on structure search, upload and the standardization of the structural information associated with toxicity data: http://www.epa.
gov/ncct/dsstox/index.html
DTome
Information on adverse drug–drug interactions: http://bioinfo.mc.vanderbilt.edu/
DTome/
EAFUS
US FDA/CFSAN Everything Added to Food Database. It contains data about
ingredients, which are added to food: http://www.accessdata.fda.gov/scripts/fcn/
fcnnavigation.cfm?rpt=eafuslisting
ECETOC
European Centre for Ecotoxicology and Toxicology of Chemicals: http://www.
ecetoc.org/
ECOTOX
US EPA toxicity database includes information about water and soil organisms:
http://cfpub.epa.gov/ecotox/
ESIS
European chemical Substances Information System provides information about
the risks and safety of chemical compounds: http://esis.jrc.ec.europa.eu/
eTOX Library Contains links to articles of toxicological relevance (data that can be used for
modeling purposes, computational models, and toxicity mechanisms), public
databases, standardized vocabularies and modeling tools: http://cadd.imim.es/
etox-library/
EXTOXNET The database provides information about toxicity of pesticides: http://extoxnet.
orst.edu/ghindex.html
FAERS
The FDA Adverse Event Reporting System (FAERS) is a database that contains
information on the adverse event and medication error reports submitted to
FDA. The database is designed to support the FDA’s post-marketing safety surveillance program for drug and therapeutic biologic products: http://www.fda.
gov/Drugs/GuidanceComplianceRegulatoryInformation/Surveillance/AdverseDrugEffects/default.htm
FDA Poisonous Plant
Database
Database US FDA/ CFSAN with references to the scientific literature describes
the study of toxic properties of plants: http://www.accessdata.fda.gov/scripts/
plantox/index.cfm
GAC
US NIH/NIEHS Genetic Alterations in Cancer database; Quantitatively
described mutations found in the tumors induced by the compounds present in
the environment: http://www.niehs.nih.gov/research/resources/databases/gac/
index.cfm
Gene-Tox
Expertly curate data of genetic toxicity tests for more than 3000 chemical compounds of US NLM: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?GENETOX
HERA
Human and Environmental Risk Assessment on Ingredients and Household
Cleaning Products. It contains toxicological information about ingredients supplied by European manufacturers: http://www.heraproject.com/RiskAssessment.
cfm
Household
Products
Database
Database provided by Department of Health and Human Services with Material
Safety Data Sheets. It includes products used in the household with the assessment of their effects on human health and chemicals, which are presented in
these products: http://hpd.nlm.nih.gov/
Table 11.1 (continued)
A. Zakharov and A. Lagunin
Database
Definition
DRAR-CPI
Prediction of Drug Repositioning and Adverse Reaction via Chemical-Protein
Interactome: http://cpi.bio-x.cn/drar/
Drugs@FDA Information about the US FDA approved drug products: http://www.fda.gov/
Drugs/InformationOnDrugs/ucm135821.htm
DSSTox
Distributed Structure-Searchable Toxicity Database Network. Distributed toxicity databases, which is focused on structure search, upload and the standardization of the structural information associated with toxicity data: http://www.epa.
gov/ncct/dsstox/index.html
DTome
Information on adverse drug–drug interactions: http://bioinfo.mc.vanderbilt.edu/
DTome/
EAFUS
US FDA/CFSAN Everything Added to Food Database. It contains data about
ingredients, which are added to food: http://www.accessdata.fda.gov/scripts/fcn/
fcnnavigation.cfm?rpt=eafuslisting
ECETOC
European Centre for Ecotoxicology and Toxicology of Chemicals: http://www.
ecetoc.org/
ECOTOX
US EPA toxicity database includes information about water and soil organisms:
http://cfpub.epa.gov/ecotox/
ESIS
European chemical Substances Information System provides information about
the risks and safety of chemical compounds: http://esis.jrc.ec.europa.eu/
eTOX Library Contains links to articles of toxicological relevance (data that can be used for
modeling purposes, computational models, and toxicity mechanisms), public
databases, standardized vocabularies and modeling tools: http://cadd.imim.es/
etox-library/
EXTOXNET The database provides information about toxicity of pesticides: http://extoxnet.
orst.edu/ghindex.html
FAERS
The FDA Adverse Event Reporting System (FAERS) is a database that contains
information on the adverse event and medication error reports submitted to
FDA. The database is designed to support the FDA’s post-marketing safety surveillance program for drug and therapeutic biologic products: http://www.fda.
gov/Drugs/GuidanceComplianceRegulatoryInformation/Surveillance/AdverseDrugEffects/default.htm
FDA Poisonous Plant
Database
Database US FDA/ CFSAN with references to the scientific literature describes
the study of toxic properties of plants: http://www.accessdata.fda.gov/scripts/
plantox/index.cfm
GAC
US NIH/NIEHS Genetic Alterations in Cancer database; Quantitatively
described mutations found in the tumors induced by the compounds present in
the environment: http://www.niehs.nih.gov/research/resources/databases/gac/
index.cfm
Gene-Tox
Expertly curate data of genetic toxicity tests for more than 3000 chemical compounds of US NLM: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?GENETOX
HERA
Human and Environmental Risk Assessment on Ingredients and Household
Cleaning Products. It contains toxicological information about ingredients supplied by European manufacturers: http://www.heraproject.com/RiskAssessment.
cfm
Household
Products
Database
Database provided by Department of Health and Human Services with Material
Safety Data Sheets. It includes products used in the household with the assessment of their effects on human health and chemicals, which are presented in
these products: http://hpd.nlm.nih.gov/
Table 11.1 (continued)