94
N. R. Jena et al.
220. Morikawa K, Matsumoto O, Tsujimoto M, Katayanagi K, Ariyoshi M, Doi T, Ikehara M,
Inaoka T, Ohtsuka E (1992) X-ray structure of T4 endonuclease V: an excision repair enzyme specific for a pyrimidine dimer. Science 256:523–526
221. Vassylyev DG, Kashiwagi T, Mikami Y, Ariyoshi M, Iwai S, Ohtsuka E, Morikawa K
(1995) Atomic model of a pyrimidine dimer excision repair enzyme complexed with a
DNA substrate: structural basis for damaged DNA recognition. Cell 83:773–782
222. Cao C, Jiang YL, Stivers JT, Song F (2007) Dynamic opening of DNA during the enzymatic search for a damaged base. Nat Struct Mol Biol 11:1230–1236
223. Parker JB, Bianchet MA, Krosky DJ, Friedman JI, Amzel LM, Stivers JT (2007) Enzymatic
capture of an extrahelical thymine in the search for uracil in DNA. Nature 449:433–437
224. Qi Y, Spong MC, Nam K, Karplus M, Verdine GL (2010) Entrapment and structure of
an extrahelical guanine attempting to enter the active site of a bacterial DNA glycosylase
MutM. J Biol Chem 285:1468–1478
225. Osman R, Fuxreiter M, Luo N (2000) Specificity of damage recognition and catalysis of
DNA repair. Computer Chem 24:331–339
226. Brooks SC, Adhikary S, Rubinson EH, Eichman BF (2013) Recent advances in the structural mechanisms of DNA glycosylases. Prot Proteom 1834:247–271
227. Jena NR, Shukla PK, Jena HS, Mishra PC, Suhai S (2009) O6-Methylguanine repair by
O6-alkylguanine-DNA alkyltransferase. J Phys Chem B 113:16285–16290
228. McCann JAB, Berti PJJ (2008) Transition state analysis of the DNA repair enzyme MutY.
J Am Chem Soc 130:5789–5797
229. Tiwari S, Agnihotri N, Mishra PC (2011) Quantum theoretical study of cleavage of the
glycosidic bond of 2’-deoxyadenosine: base excision-repair mechanism of DNA by MutY.
J Phys Chem B 115:3200–3207
N. R. Jena et al.
220. Morikawa K, Matsumoto O, Tsujimoto M, Katayanagi K, Ariyoshi M, Doi T, Ikehara M,
Inaoka T, Ohtsuka E (1992) X-ray structure of T4 endonuclease V: an excision repair enzyme specific for a pyrimidine dimer. Science 256:523–526
221. Vassylyev DG, Kashiwagi T, Mikami Y, Ariyoshi M, Iwai S, Ohtsuka E, Morikawa K
(1995) Atomic model of a pyrimidine dimer excision repair enzyme complexed with a
DNA substrate: structural basis for damaged DNA recognition. Cell 83:773–782
222. Cao C, Jiang YL, Stivers JT, Song F (2007) Dynamic opening of DNA during the enzymatic search for a damaged base. Nat Struct Mol Biol 11:1230–1236
223. Parker JB, Bianchet MA, Krosky DJ, Friedman JI, Amzel LM, Stivers JT (2007) Enzymatic
capture of an extrahelical thymine in the search for uracil in DNA. Nature 449:433–437
224. Qi Y, Spong MC, Nam K, Karplus M, Verdine GL (2010) Entrapment and structure of
an extrahelical guanine attempting to enter the active site of a bacterial DNA glycosylase
MutM. J Biol Chem 285:1468–1478
225. Osman R, Fuxreiter M, Luo N (2000) Specificity of damage recognition and catalysis of
DNA repair. Computer Chem 24:331–339
226. Brooks SC, Adhikary S, Rubinson EH, Eichman BF (2013) Recent advances in the structural mechanisms of DNA glycosylases. Prot Proteom 1834:247–271
227. Jena NR, Shukla PK, Jena HS, Mishra PC, Suhai S (2009) O6-Methylguanine repair by
O6-alkylguanine-DNA alkyltransferase. J Phys Chem B 113:16285–16290
228. McCann JAB, Berti PJJ (2008) Transition state analysis of the DNA repair enzyme MutY.
J Am Chem Soc 130:5789–5797
229. Tiwari S, Agnihotri N, Mishra PC (2011) Quantum theoretical study of cleavage of the
glycosidic bond of 2’-deoxyadenosine: base excision-repair mechanism of DNA by MutY.
J Phys Chem B 115:3200–3207
