276
F. Shi et al.
11. B.J. Antony, M.D. Abràmoff, M.M. Harper, J. Woojin, E.H. Sohn, Y.H. Kwon, R. Kardon,
M.K. Garvin, A combined machine-learning and graph-based framework for the segmentation
of retinal surfaces in sd-oct volumes. Biomed. Opt. Express 4(12), 2712–2728 (2013)
12. A. Lang, A. Carass, M. Hauser, E.S. Sotirchos, P.A. Calabresi, H.S. Ying, J.L. Prince, Retinal layer segmentation of macular OCT images using boundary classification. Biomed. Opt.
Express 4, 1133–1152 (2013)
13. P.A. Dufour, L. Ceklic, H. Abdillahi, S. Schröder, S. De Dzanet, U. Wolf-Schnurrbusch, J.
Kowal, Graph-based multi-surface segmentation of OCT data using trained hard and soft constraints. IEEE Trans. Med. Imag. 32(3), 531–543 (2013)
14. The Iowa Reference Algorithms (Iowa Institute for Biomedical Imaging, Iowa City, IA.)
(Online). http://www.biomed-imaging.uiowa.edu/downloads/
15. F. Shi, X. Chen, H. Zhao, W. Zhu, D. Xiang, E. Gao, M. Sonka, H. Chen, Automated 3D retinal layer segmentation of macular optical coherence tomography images with serous
pigment epithelial detachments. IEEE Trans. Med. Imag. 34(2), 441–452 (2015)
16. C.E. Al-Haddad, G.M. Mollayess, C.G. Cherfan, D.F. Jaafar, Z.F. Bashshur, Retinal nerve fibre
layer and macular thickness in amblyopia as measured by spectral-domain optical coherence
tomography. Br. J. Ophthalmol. 95, 1696–1699 (2011)
17. D. Cabrera G.M. DeBuc, Somfai, Early detection of retinal thickness changes in diabetes using
optical coherence tomography. Med. Sci. Monit. 16, MT15-21 (2010)
18. E.C. Davies, K.M. Galetta, D.J. Sackel, L.S. Talman, E.M. Frohman, P.A. Calabresi, S.L.
Galetta, L.J. Balcer, Retinal ganglion cell layer volumetric assessment by spectral-domain
optical coherence tomography in multiple sclerosis: application of a high-precision manual
estimation technique. J. Neuroophthalmol. 31, 260–264 (2011)
19. N. Demirkaya, H.W. van Dijk, S.M. van Schuppen, M.D. Abramoff, M.K. Garvin, M. Sonka,
R.O. Schlingemann, F.D. Verbraak, Effect of age on individual retinal layer thickness in normal
eyes as measured with spectral-domain optical coherence tomography. Invest. Ophthalmol. Vis.
Sci. 54, 4934–4940 (2013)
20. N.R. Kim, S. Hong, J.H. Kim, S.S. Rho, G.J. Seong, C.Y. Kim, Comparison of Macular Ganglion cell complex thickness by Fourier-Domain OCT in normal tension Glaucoma and primary
open-angle Glaucoma. J. Glaucoma 22(2), 133–139 (2013)
21. X. Chen, P. Hou, C. Jin, W. Zhu, X. Luo, F. Shi, M. Sonka, H. Chen, Quantitative analysis
of retinal layers’ optical intensities on 3D optical coherence tomography. Invest. Ophthalmol.
Vis. Sci. 54(10), 6846–6851 (2013)
22. H. Chen, X. Chen, Z. Qiu, D. Xiang, W. Chen, F. Shi, J. Zheng, W. Zhu, M. Sonka, Quantitative
analysis of retinal layers’ optical intensities on 3D optical coherence tomography for central
retinal artery occlusion. Sci. Rep., 5, Article number: 9269
23. X. Chen, L. Zhang, E.H. Sohn, K. Lee, M. Niemeijer, J. Chen, M. Sonka, M.D. Abramoff,
Quantification of external limiting membrane disruption caused by diabetic macular edema
from SD-OCT. Invest. Ophthalmol. Vis. Sci. 53(13), 8042–8048 (2012)
24. W. Zhu, H. Chen, H. Zhao, B. Tian, L. Wang, F. Shi, D. Xiang, X. Luo, E. Gao, L. Zhang, Y.
Yin, X. Chen, Automatic three-dimensional detection of photoreceptor ellipsoid zone disruption
caused by trauma in the OCT. Sci. Rep. 6, 25433 (2016)
25. S. Mrejen, D. Sarraf, S.K. Mukkamala, K.B. Freund, Multimodal imaging of pigment epithelial
detachment: a guide to evaluation. Retina 33(9), 1735–1762 (2013)
26. S. Zayit-Soudry, I. Moroz, A. Loewenstein, Retinal pigment epithelial detachment. Surv. Ophthalmol. 52(3), 227–243 (2007)
27. P.A. Keane, P.J. Patel, S. Liakopoulos, F.M. Heussen, S.R. Sadda, A. Tufail, Evaluation of agerelated macular degeneration with optical coherence tomography. Surv. Ophthalmol. 57(5),
389–414 (2012)
28. K. Lee, M. Niemeijer, M.K. Garvin, Y.H. Kwon, M. Sonka, M.D. Abràmoff, Segmentation
of the optic disc in 3-D OCT scans of the optic nerve head. IEEE Trans. Med. Imag. 29(1),
159–168 (2010)
29. K. Li, X. Wu, D.Z. Chen, M. Sonka, Optimal surface segmentation in volumetric images—a
graph-theoretic approach. IEEE Trans. Pattern Anal. Mach. Intell. 28(1), 119–134 (2006)
F. Shi et al.
11. B.J. Antony, M.D. Abràmoff, M.M. Harper, J. Woojin, E.H. Sohn, Y.H. Kwon, R. Kardon,
M.K. Garvin, A combined machine-learning and graph-based framework for the segmentation
of retinal surfaces in sd-oct volumes. Biomed. Opt. Express 4(12), 2712–2728 (2013)
12. A. Lang, A. Carass, M. Hauser, E.S. Sotirchos, P.A. Calabresi, H.S. Ying, J.L. Prince, Retinal layer segmentation of macular OCT images using boundary classification. Biomed. Opt.
Express 4, 1133–1152 (2013)
13. P.A. Dufour, L. Ceklic, H. Abdillahi, S. Schröder, S. De Dzanet, U. Wolf-Schnurrbusch, J.
Kowal, Graph-based multi-surface segmentation of OCT data using trained hard and soft constraints. IEEE Trans. Med. Imag. 32(3), 531–543 (2013)
14. The Iowa Reference Algorithms (Iowa Institute for Biomedical Imaging, Iowa City, IA.)
(Online). http://www.biomed-imaging.uiowa.edu/downloads/
15. F. Shi, X. Chen, H. Zhao, W. Zhu, D. Xiang, E. Gao, M. Sonka, H. Chen, Automated 3D retinal layer segmentation of macular optical coherence tomography images with serous
pigment epithelial detachments. IEEE Trans. Med. Imag. 34(2), 441–452 (2015)
16. C.E. Al-Haddad, G.M. Mollayess, C.G. Cherfan, D.F. Jaafar, Z.F. Bashshur, Retinal nerve fibre
layer and macular thickness in amblyopia as measured by spectral-domain optical coherence
tomography. Br. J. Ophthalmol. 95, 1696–1699 (2011)
17. D. Cabrera G.M. DeBuc, Somfai, Early detection of retinal thickness changes in diabetes using
optical coherence tomography. Med. Sci. Monit. 16, MT15-21 (2010)
18. E.C. Davies, K.M. Galetta, D.J. Sackel, L.S. Talman, E.M. Frohman, P.A. Calabresi, S.L.
Galetta, L.J. Balcer, Retinal ganglion cell layer volumetric assessment by spectral-domain
optical coherence tomography in multiple sclerosis: application of a high-precision manual
estimation technique. J. Neuroophthalmol. 31, 260–264 (2011)
19. N. Demirkaya, H.W. van Dijk, S.M. van Schuppen, M.D. Abramoff, M.K. Garvin, M. Sonka,
R.O. Schlingemann, F.D. Verbraak, Effect of age on individual retinal layer thickness in normal
eyes as measured with spectral-domain optical coherence tomography. Invest. Ophthalmol. Vis.
Sci. 54, 4934–4940 (2013)
20. N.R. Kim, S. Hong, J.H. Kim, S.S. Rho, G.J. Seong, C.Y. Kim, Comparison of Macular Ganglion cell complex thickness by Fourier-Domain OCT in normal tension Glaucoma and primary
open-angle Glaucoma. J. Glaucoma 22(2), 133–139 (2013)
21. X. Chen, P. Hou, C. Jin, W. Zhu, X. Luo, F. Shi, M. Sonka, H. Chen, Quantitative analysis
of retinal layers’ optical intensities on 3D optical coherence tomography. Invest. Ophthalmol.
Vis. Sci. 54(10), 6846–6851 (2013)
22. H. Chen, X. Chen, Z. Qiu, D. Xiang, W. Chen, F. Shi, J. Zheng, W. Zhu, M. Sonka, Quantitative
analysis of retinal layers’ optical intensities on 3D optical coherence tomography for central
retinal artery occlusion. Sci. Rep., 5, Article number: 9269
23. X. Chen, L. Zhang, E.H. Sohn, K. Lee, M. Niemeijer, J. Chen, M. Sonka, M.D. Abramoff,
Quantification of external limiting membrane disruption caused by diabetic macular edema
from SD-OCT. Invest. Ophthalmol. Vis. Sci. 53(13), 8042–8048 (2012)
24. W. Zhu, H. Chen, H. Zhao, B. Tian, L. Wang, F. Shi, D. Xiang, X. Luo, E. Gao, L. Zhang, Y.
Yin, X. Chen, Automatic three-dimensional detection of photoreceptor ellipsoid zone disruption
caused by trauma in the OCT. Sci. Rep. 6, 25433 (2016)
25. S. Mrejen, D. Sarraf, S.K. Mukkamala, K.B. Freund, Multimodal imaging of pigment epithelial
detachment: a guide to evaluation. Retina 33(9), 1735–1762 (2013)
26. S. Zayit-Soudry, I. Moroz, A. Loewenstein, Retinal pigment epithelial detachment. Surv. Ophthalmol. 52(3), 227–243 (2007)
27. P.A. Keane, P.J. Patel, S. Liakopoulos, F.M. Heussen, S.R. Sadda, A. Tufail, Evaluation of agerelated macular degeneration with optical coherence tomography. Surv. Ophthalmol. 57(5),
389–414 (2012)
28. K. Lee, M. Niemeijer, M.K. Garvin, Y.H. Kwon, M. Sonka, M.D. Abràmoff, Segmentation
of the optic disc in 3-D OCT scans of the optic nerve head. IEEE Trans. Med. Imag. 29(1),
159–168 (2010)
29. K. Li, X. Wu, D.Z. Chen, M. Sonka, Optimal surface segmentation in volumetric images—a
graph-theoretic approach. IEEE Trans. Pattern Anal. Mach. Intell. 28(1), 119–134 (2006)