Chapter 7
Quantitative Analysis of Retinal Layers’
Optical Intensities Based on Optical
Coherence Tomography
Enting Gao, Fei Shi, Haoyu Chen and Xinjian Chen
In addition to the morphologic parameters of retinal structures, OCT images also
provide the signal/reflection intensity information, which is however much less studied. This chapter introduces several studies on the quantitative analysis of the retinal
layers’ optical intensity, both for normal subjects and for patients with central retinal
artery occlusion.
7.1 Introduction
Optical coherence tomography (OCT) is an in vivo, non-invasive imaging technology providing cross-sectional images of the retina structure [1]. It has significantly
improved our understanding in eye physiology and in pathogenesis of ocular diseases.
It also greatly helped the clinicians in diagnosis and management of retinal diseases
[2]. OCT not only allows observation of the morphology of normal or disordered retinal tissue, but also provides quantitative measurement. Currently, most commercial
OCT machines provide automatic measurements of the peripapillary retinal nerve
fiber layer (RNFL) thickness and total macular retinal thickness. Advanced imaging
E. Gao · F. Shi · X. Chen
School of Electronics and Information Engineering, Soochow University,
Suzhou, China
X. Chen (B)
State Key Laboratory of Radiation Medicine and Protection, Soochow University,
Suzhou, China
e-mail: xjchen@suda.edu.cn
H. Chen
Joint Shantou International Eye Center, Shantou University,
Chinese University of Hong Kong, Shantou, China
© Science Press and Springer Nature Singapore Pte Ltd. 2019
X. Chen et al. (eds.), Retinal Optical Coherence Tomography Image Analysis,
Biological and Medical Physics, Biomedical Engineering,
https://doi.org/10.1007/978-981-13-1825-2_7
169
Quantitative Analysis of Retinal Layers’
Optical Intensities Based on Optical
Coherence Tomography
Enting Gao, Fei Shi, Haoyu Chen and Xinjian Chen
In addition to the morphologic parameters of retinal structures, OCT images also
provide the signal/reflection intensity information, which is however much less studied. This chapter introduces several studies on the quantitative analysis of the retinal
layers’ optical intensity, both for normal subjects and for patients with central retinal
artery occlusion.
7.1 Introduction
Optical coherence tomography (OCT) is an in vivo, non-invasive imaging technology providing cross-sectional images of the retina structure [1]. It has significantly
improved our understanding in eye physiology and in pathogenesis of ocular diseases.
It also greatly helped the clinicians in diagnosis and management of retinal diseases
[2]. OCT not only allows observation of the morphology of normal or disordered retinal tissue, but also provides quantitative measurement. Currently, most commercial
OCT machines provide automatic measurements of the peripapillary retinal nerve
fiber layer (RNFL) thickness and total macular retinal thickness. Advanced imaging
E. Gao · F. Shi · X. Chen
School of Electronics and Information Engineering, Soochow University,
Suzhou, China
X. Chen (B)
State Key Laboratory of Radiation Medicine and Protection, Soochow University,
Suzhou, China
e-mail: xjchen@suda.edu.cn
H. Chen
Joint Shantou International Eye Center, Shantou University,
Chinese University of Hong Kong, Shantou, China
© Science Press and Springer Nature Singapore Pte Ltd. 2019
X. Chen et al. (eds.), Retinal Optical Coherence Tomography Image Analysis,
Biological and Medical Physics, Biomedical Engineering,
https://doi.org/10.1007/978-981-13-1825-2_7
169