231
Table 6.11 Extraction techniques that proved the cell disruption ability of deep eutectic solvents
Extraction medium Target compounds
Selected DES HBA/HBD
(molar ratio)
Extraction technique
Disruption degree order
References
Radix Salviae
Miltiorrhizae
Rosmarinic acid,
lithospermic acid,
salvianolic acid B,
salvianolic acid A,
tanshinone 2 A
Choline chloride/1,2propanediol
(1:1) + 20 vol% of water
Microwave extraction
DES > 75% methanol > water
Chen et al.
(2016)
Green tea
(Camellia sinensis)
Catechins:
epigallocatechin-3-gallate
81% betaine/
glycerol/D-glucose (4:20:1)
Ultrasound
microextraction
81% DES > methanol or 70%
methanol
Jeong et al.
(2017)
Morus alba leaves Phenolic compounds
Choline chloride/citric acid
(2:1)
Ultrasound
microextraction
DES > 75% methanol > water
Zhou et al.
(2018)
Scutellaria
baicalensis
Georgi
(Chinese herbal
medicine)
Baicalin
Decanoic acid/
tetrabutylammonium
chloride (1: 2) + 30% v/v
water
Microwave extraction
or ultrasound extraction
or hot reflux extraction
Microwave extraction > ultrasound
extraction > hot reflux extraction.
Also, DES > 70 vol% ethanol
Wang et al.
(2018)
DES
deep eutectic solvent, HBA
hydrogen bond acceptor, HBD
hydrogen bond donor
6 Methods for Extraction of Bioactive Compounds from Plant and Animal Matter…