213
Table 6.9 Examples of the application of solid-phase microextraction techniques with deep
eutectic solvents as extraction solvents
Extraction
medium
Target compounds
DES:HBA/HBD (molar
ratio)
Sorbent type
References
Grape juice
and
mineralized
drinking
water
Organic acids: benzoic
acid, p-anisic acid,
salicylic acid, and
cinnamic acid
Choline chloride/urea
(1:2)
Silica cartridge
was prepared in
DES to obtain
nitro-substituted
tris(indolyl)
methanemodified silica
Wang et al.
(2016)
Phyllanthus
flexuosus
(dried plant
materials)
Cleistanthol
Choline chloride/
glycerol (1:2)
DES-modified
anion exchange
resin. Positive
choline groups
of DES can
make
electrostatic
interactions with
the negatively
charged analyte.
Gan et al.
(2016)
Salvia
miltiorrhiza
Bunge
Tanshinones:
cryptotanshinone,
tanshinone I, and
tanshinone IIA
Choline chloride/
ethylene glycol (1:3),
choline chloride/
glycerol (1:3), choline
chloride/1,2-butanediol
(1:4), choline
chloride/1,3-butanediol
(1:4), choline
chloride/1,4-butanediol
(1:4), and choline
chloride/2,3-butanediol
(1:4)
Beads
Wang et al.
(2016)
Proteins
Bovine serum
albumin, ovalbumin,
lysozyme, and bovine
hemoglobin
Choline chloride/urea
(1:1), choline
chloride/D (+)-glucose
(1:1), choline chloride/
ethylene glycol (1:2),
and choline chloride/
glycerol (1:1)
Magnetic
graphene oxide
impregnated
with DES
(Fe 3 O 4 @
GO-DES);
optimal DES:
choline
chloride/D-(+)glucose (1:1)
Huang
et al.
(2015)
Bovine whole
blood
Bovine serum
albumin, ovalbumin,
lysozyme, and bovine
hemoglobin
Choline chloride/
glycerol (1:1), choline
chloride/ethylene
glycol (1:2), choline
chloride/D-glucose
(2:1), and choline
chloride/D-sorbitol
(1:1)
Fe 3 O 4 -NH 2 @
GO@DES
magnetic
nanoparticles
using choline
chloride/glycerol
(1:1) as the best
DES
Xu et al.
(2016a, b)
(continued)
6 Methods for Extraction of Bioactive Compounds from Plant and Animal Matter…