25. Hamm P, Lim M, DeGrado WF, Hochstrasser RM (1999) The two-dimensional IR nonlinear
spectroscopy of a cyclic penta-peptide in relation to its three-dimensional structure. Proc Natl Acad
Sci USA 96:2036–2041. doi:10.1073/Pnas.96.5.2036
26. Kleckner IR, Foster MP (2011) An introduction to NMR-based approaches for measuring protein
dynamics. Biochim Biophys Acta Proteins Proteom 1814:942–968. doi:10.1016/j.bbapap.2010.10.
012
27. Haller JD, Schanda P (2013) Amplitudes and time scales of picosecond-to-microsecond motion in
proteins studied by solid-state NMR: a critical evaluation of experimental approaches and application to crystalline ubiquitin. J Biomol NMR 57:263–280. doi:10.1007/s10858-013-9787-x
28. Sapienza P, Lee A (2010) Using NMR to study fast dynamics in proteins: methods and applications.
Curr Opin Pharmacol 10:723–730. doi:10.1016/j.coph.2010.09.006.Using
29. Johnson PJM, Koziol KL, Hamm P (2017) Quantifying biomolecular recognition with site-specific
2D infrared probes. J Phys Chem Lett 8:2280–2284. doi:10.1021/acs.jpclett.7b00742
30. Ghosh A, Ostrander JS, Zanni MT (2017) Watching proteins wiggle: mapping structures with twodimensional infrared spectroscopy. Chem Rev. doi:10.1021/acs.chemrev.6b00582
31. Muller EA, Pollard B, Raschke MB (2015) Infrared chemical nano-imaging: accessing structure,
coupling, and dynamics on molecular length scales. J Phys Chem Lett 6:1275–1284. doi:10.1021/
acs.jpclett.5b00108
32. Fayer MD (2009) Dynamics of liquids, molecules, and proteins measured with ultrafast 2D IR
vibrational echo chemical exchange spectroscopy. Annu Rev Phys Chem 60:21–38. doi:10.1146/
annurev-physchem-073108-112712
33. Cho M (2008) Coherent two-dimensional optical spectroscopy. Chem Rev 108:1331–1418. doi:10.
1021/cr078377b
34. Remorino A, Hochstrasser RM (2012) Three-dimensional structures by two- dimensional vibrational spectroscopy. Acc Chem Res 45:1896–1905. doi:10.1021/ar3000025
35. Zanni MT, Hochstrasser RM (2001) Two-dimensional infrared spectroscopy: a promising new
method for the time resolution of structures. Curr Opin Struct Biol 11:516–522
36. Kim YS, Hochstrasser RM (2009) Applications of 2D IR spectroscopy to peptides, proteins, and
hydrogen-bond dynamics. J Phys Chem B 113:8231–8251. doi:10.1021/jp8113978
37. Woutersen S, Hamm P (2002) Nonlinear two-dimensional vibrational spectroscopy of peptides.
J Phys Condens Matter 1035:R1035–R1062
38. Hamm P, Helbing J, Bredenbeck J (2008) Two-dimensional infrared spectroscopy of photoswitchable peptides. Annu Rev Phys Chem 59:291–317. doi:10.1146/annurev.physchem.59.032607.
093757
39. Bredenbeck J, Helbing J, Kolano C, Hamm P (2007) Ultrafast 2D–IR spectroscopy of transient
species. ChemPhysChem 8:1747–1756. doi:10.1002/cphc.200700148
40. Simpson N, Hunt NT (2015) Ultrafast 2D-IR spectroscopy of haemoproteins. Int Rev Phys Chem
34:361–383. doi:10.1080/0144235X.2015.1061793
41. Hunt NT (2009) 2D-IR spectroscopy: ultrafast insights into biomolecule structure and function.
Chem Soc Rev 38:1837–1848. doi:10.1039/b819181f
42. Strasfeld DB, Shim S-H, Zanni MT (2009) New Advances in mid-IR pulse shaping and its
application to 2D IR spectroscopy and ground-state coherent control. Adv Chem Phys 141:1–28
43. Chen H, Bian H, Li J et al (2012) Ultrafast multiple-mode multiple-dimensional vibrational
spectroscopy. Int Rev Phys Chem 31:469–565. doi:10.1080/0144235X.2012.733116
44. Le Sueur AL, Horness RE, Thielges M (2015) Applications of two-dimensional infrared spectroscopy. Analyst 140:4336–4349. doi:10.1039/C5AN00558B
45. Finkelstein IJ, Zheng J, Ishikawa H et al (2007) Probing dynamics of complex molecular systems
with ultrafast 2D IR vibrational echo spectroscopy. Phys Chem Chem Phys 9:1533–1549. doi:10.
1039/b618158a
46. Ge N-H, Hochstrasser RM (2002) Femtosecond two-dimensional infrared spectroscopy: IR-COSY
and THIRSTY. PhysChemComm 5:17. doi:10.1039/b109935c
47. Ganim Z, Hoi SC, Smith AW et al (2008) Amide I two-dimensional infrared spectroscopy of
proteins. Acc Chem Res 41:432–441. doi:10.1021/ar700188n
48. Mukamel S (2000) Multidimensional femtosecond correlation spectroscopies of electronic and
vibrationnal excitations. Annu Rev Phys Chem 51:691–729
49. Shim S-H, Zanni MT (2009) How to turn your pump-probe instrument into a multidimensional
spectrometer: 2D IR and Vis spectroscopies via pulse shaping. Phys Chem Chem Phys 11:748–761.
doi:10.1039/b813817f
Top Curr Chem (Z) (2017) 375:86
123
190
Reprinted from the journal
spectroscopy of a cyclic penta-peptide in relation to its three-dimensional structure. Proc Natl Acad
Sci USA 96:2036–2041. doi:10.1073/Pnas.96.5.2036
26. Kleckner IR, Foster MP (2011) An introduction to NMR-based approaches for measuring protein
dynamics. Biochim Biophys Acta Proteins Proteom 1814:942–968. doi:10.1016/j.bbapap.2010.10.
012
27. Haller JD, Schanda P (2013) Amplitudes and time scales of picosecond-to-microsecond motion in
proteins studied by solid-state NMR: a critical evaluation of experimental approaches and application to crystalline ubiquitin. J Biomol NMR 57:263–280. doi:10.1007/s10858-013-9787-x
28. Sapienza P, Lee A (2010) Using NMR to study fast dynamics in proteins: methods and applications.
Curr Opin Pharmacol 10:723–730. doi:10.1016/j.coph.2010.09.006.Using
29. Johnson PJM, Koziol KL, Hamm P (2017) Quantifying biomolecular recognition with site-specific
2D infrared probes. J Phys Chem Lett 8:2280–2284. doi:10.1021/acs.jpclett.7b00742
30. Ghosh A, Ostrander JS, Zanni MT (2017) Watching proteins wiggle: mapping structures with twodimensional infrared spectroscopy. Chem Rev. doi:10.1021/acs.chemrev.6b00582
31. Muller EA, Pollard B, Raschke MB (2015) Infrared chemical nano-imaging: accessing structure,
coupling, and dynamics on molecular length scales. J Phys Chem Lett 6:1275–1284. doi:10.1021/
acs.jpclett.5b00108
32. Fayer MD (2009) Dynamics of liquids, molecules, and proteins measured with ultrafast 2D IR
vibrational echo chemical exchange spectroscopy. Annu Rev Phys Chem 60:21–38. doi:10.1146/
annurev-physchem-073108-112712
33. Cho M (2008) Coherent two-dimensional optical spectroscopy. Chem Rev 108:1331–1418. doi:10.
1021/cr078377b
34. Remorino A, Hochstrasser RM (2012) Three-dimensional structures by two- dimensional vibrational spectroscopy. Acc Chem Res 45:1896–1905. doi:10.1021/ar3000025
35. Zanni MT, Hochstrasser RM (2001) Two-dimensional infrared spectroscopy: a promising new
method for the time resolution of structures. Curr Opin Struct Biol 11:516–522
36. Kim YS, Hochstrasser RM (2009) Applications of 2D IR spectroscopy to peptides, proteins, and
hydrogen-bond dynamics. J Phys Chem B 113:8231–8251. doi:10.1021/jp8113978
37. Woutersen S, Hamm P (2002) Nonlinear two-dimensional vibrational spectroscopy of peptides.
J Phys Condens Matter 1035:R1035–R1062
38. Hamm P, Helbing J, Bredenbeck J (2008) Two-dimensional infrared spectroscopy of photoswitchable peptides. Annu Rev Phys Chem 59:291–317. doi:10.1146/annurev.physchem.59.032607.
093757
39. Bredenbeck J, Helbing J, Kolano C, Hamm P (2007) Ultrafast 2D–IR spectroscopy of transient
species. ChemPhysChem 8:1747–1756. doi:10.1002/cphc.200700148
40. Simpson N, Hunt NT (2015) Ultrafast 2D-IR spectroscopy of haemoproteins. Int Rev Phys Chem
34:361–383. doi:10.1080/0144235X.2015.1061793
41. Hunt NT (2009) 2D-IR spectroscopy: ultrafast insights into biomolecule structure and function.
Chem Soc Rev 38:1837–1848. doi:10.1039/b819181f
42. Strasfeld DB, Shim S-H, Zanni MT (2009) New Advances in mid-IR pulse shaping and its
application to 2D IR spectroscopy and ground-state coherent control. Adv Chem Phys 141:1–28
43. Chen H, Bian H, Li J et al (2012) Ultrafast multiple-mode multiple-dimensional vibrational
spectroscopy. Int Rev Phys Chem 31:469–565. doi:10.1080/0144235X.2012.733116
44. Le Sueur AL, Horness RE, Thielges M (2015) Applications of two-dimensional infrared spectroscopy. Analyst 140:4336–4349. doi:10.1039/C5AN00558B
45. Finkelstein IJ, Zheng J, Ishikawa H et al (2007) Probing dynamics of complex molecular systems
with ultrafast 2D IR vibrational echo spectroscopy. Phys Chem Chem Phys 9:1533–1549. doi:10.
1039/b618158a
46. Ge N-H, Hochstrasser RM (2002) Femtosecond two-dimensional infrared spectroscopy: IR-COSY
and THIRSTY. PhysChemComm 5:17. doi:10.1039/b109935c
47. Ganim Z, Hoi SC, Smith AW et al (2008) Amide I two-dimensional infrared spectroscopy of
proteins. Acc Chem Res 41:432–441. doi:10.1021/ar700188n
48. Mukamel S (2000) Multidimensional femtosecond correlation spectroscopies of electronic and
vibrationnal excitations. Annu Rev Phys Chem 51:691–729
49. Shim S-H, Zanni MT (2009) How to turn your pump-probe instrument into a multidimensional
spectrometer: 2D IR and Vis spectroscopies via pulse shaping. Phys Chem Chem Phys 11:748–761.
doi:10.1039/b813817f
Top Curr Chem (Z) (2017) 375:86
123
190
Reprinted from the journal