43. Ahmed E, Holmström S (2014) Siderophores in environmental research. Microb Biotechnol
7(3):196–208. https://doi.org/10.1111/1751-7915.12117
44. Nosrati R, Dehghani S, Karimi B, Yousefi M, Taghdisi SM, Abnous K, Alibolandi M,
Ramezani M (2018) Siderophore-based biosensors and nanosensors; new approach on the
development of diagnostic systems. Biosens Bioelectron 117(15):1–14. https://doi.org/10.
1016/j.bios.2018.05.057
45. Hagan A (2017) Siderophores: bacterial iron scavengers? Microbiol Sci. https://www.asm.org/
index.php/general-science-blog/item/6411
46. Behnsen J, Raffatellu M (2016) Siderophores: more than stealing iron. MBio 7(6):e01906–
e01916. https://doi.org/10.1128/mBio.01397-16
47. Aznar A, Dellagi A (2015) New insights into the role of siderophores as triggers of plant
immunity: what we can learn from animals. J Exp Bot 66:3001–3010. https://academic.oup.
com/jxb/article/66/11/3001/467272
48. Wencewicz TA, Miller MJ (2017) Sideromycins as pathogen-targeted antibiotics. In: Fisher J,
Mobashery S, Miller M (eds) Antibacterials. Topics in medicinal chemistry, vol 26. Springer,
Cham. https://doi.org/10.1007/7355_2017_19
49. De Serrano LO (2017) Biotechnology of siderophores in high-impact scientific fields. Biomol
Concepts 8(3–4):169–178. https://doi.org/10.1515/bmc-2017-0016
50. De Serrano LO, Camper AK, Richards AM (2016) An overview of siderophores for iron
acquisition in microorganisms living in the extreme. Biometals 29:551–571. https://doi.org/
10.1007/s10534-016-9949-x
51. McMillan DGG, Velasquez I, Nunn BL, Goodlett DR, Hunter KA, Lamont I, Sander SG,
Cook GM (2010) Acquisition of iron by alkaliphilic Bacillus species. Appl Environ Microbiol
76(20):6955–6961. https://doi.org/10.1128/AEM.01393-10
52. Ye Q, Roh Y, Carroll SL, Blair B, Zhou J, Zhang CL, Fields MW (2004) Alkaline anaerobic
respiration: isolation and characterization of a novel alkaliphilic and metal-reducing bacterium. Appl Environ Microbiol 70(9):5595–5602. https://doi.org/10.1128/AEM.70.9.
5595–5602.2004
53. Figueroa LS, Schwarz B, Richards AM (2015) Structural characterization of amphiphilic
siderophores produced by a soda lake isolate, Halomonas sp. SL01, reveals cysteine-,
phenylalanine- and proline-containing head groups. Extremophiles 19:1183–1192. https://
doi.org/10.1007/s00792-015-0790-x
54. Cabello P, Luque-Almagro VM, Olaya-Abril A, Saez LP, Moreno-Vivian C, Roldan MD
(2018) Assimilation of cyanide and cyano-derivatives by Pseudomonas pseudoalcaligenes
CECT5344: from omic approaches to biotechnological applications. FEMS Microbiol Lett
365:fny032. https://doi.org/10.1093/femsle/fny032
55. Ibañez MI, Cabello P, Luque-Almagro VM, Saez LP, Olaya A, Sanchez de Medina V et al
(2017) Quantitative proteomic analysis of Pseudomonas pseudoalcaligenes CECT5344 in
response to industrial cyanide-containing wastewaters using Liquid Chromatography-Mass
Spectrometry/Mass Spectrometry (LC-MS/MS). PLoS One 12(3):e0172908. https://doi.org/
10.1371/journal.pone.0172908
56. Kumar SV, Menon S, Agarwal H, Gopalakrishnan D (2017) Characterization and optimization
of bacterium isolated from soil samples for the production of siderophores. Resour Effic
Technol 3(4):434–439. https://doi.org/10.1016/j.reffit.2017.04.004
57. Sandmann G (2015) Carotenoids of biotechnological importance. Adv Biochem Eng
Biotechnol 148:449–467. https://doi.org/10.1007/10_2014_277
58. Sathasivam R, Ki J-S (2018) A review of the biological activities of microalgal carotenoids
and their potential use in healthcare and cosmetic industries. Mar Drugs 16(26):19. https://doi.
org/10.3390/md16010026
59. Avalos J, Pardo-Medina J, Parra-Rivero O, Ruger-Herreros M, Rodríguez-Ortiz R, HorneroMéndez D, Limón MC (2017) Carotenoid biosynthesis in fusarium. J Fungi 3:39. https://doi.
org/10.3390/jof3030039
Metabolites Produced by Alkaliphiles with Potential Biotechnological. . .
189
7(3):196–208. https://doi.org/10.1111/1751-7915.12117
44. Nosrati R, Dehghani S, Karimi B, Yousefi M, Taghdisi SM, Abnous K, Alibolandi M,
Ramezani M (2018) Siderophore-based biosensors and nanosensors; new approach on the
development of diagnostic systems. Biosens Bioelectron 117(15):1–14. https://doi.org/10.
1016/j.bios.2018.05.057
45. Hagan A (2017) Siderophores: bacterial iron scavengers? Microbiol Sci. https://www.asm.org/
index.php/general-science-blog/item/6411
46. Behnsen J, Raffatellu M (2016) Siderophores: more than stealing iron. MBio 7(6):e01906–
e01916. https://doi.org/10.1128/mBio.01397-16
47. Aznar A, Dellagi A (2015) New insights into the role of siderophores as triggers of plant
immunity: what we can learn from animals. J Exp Bot 66:3001–3010. https://academic.oup.
com/jxb/article/66/11/3001/467272
48. Wencewicz TA, Miller MJ (2017) Sideromycins as pathogen-targeted antibiotics. In: Fisher J,
Mobashery S, Miller M (eds) Antibacterials. Topics in medicinal chemistry, vol 26. Springer,
Cham. https://doi.org/10.1007/7355_2017_19
49. De Serrano LO (2017) Biotechnology of siderophores in high-impact scientific fields. Biomol
Concepts 8(3–4):169–178. https://doi.org/10.1515/bmc-2017-0016
50. De Serrano LO, Camper AK, Richards AM (2016) An overview of siderophores for iron
acquisition in microorganisms living in the extreme. Biometals 29:551–571. https://doi.org/
10.1007/s10534-016-9949-x
51. McMillan DGG, Velasquez I, Nunn BL, Goodlett DR, Hunter KA, Lamont I, Sander SG,
Cook GM (2010) Acquisition of iron by alkaliphilic Bacillus species. Appl Environ Microbiol
76(20):6955–6961. https://doi.org/10.1128/AEM.01393-10
52. Ye Q, Roh Y, Carroll SL, Blair B, Zhou J, Zhang CL, Fields MW (2004) Alkaline anaerobic
respiration: isolation and characterization of a novel alkaliphilic and metal-reducing bacterium. Appl Environ Microbiol 70(9):5595–5602. https://doi.org/10.1128/AEM.70.9.
5595–5602.2004
53. Figueroa LS, Schwarz B, Richards AM (2015) Structural characterization of amphiphilic
siderophores produced by a soda lake isolate, Halomonas sp. SL01, reveals cysteine-,
phenylalanine- and proline-containing head groups. Extremophiles 19:1183–1192. https://
doi.org/10.1007/s00792-015-0790-x
54. Cabello P, Luque-Almagro VM, Olaya-Abril A, Saez LP, Moreno-Vivian C, Roldan MD
(2018) Assimilation of cyanide and cyano-derivatives by Pseudomonas pseudoalcaligenes
CECT5344: from omic approaches to biotechnological applications. FEMS Microbiol Lett
365:fny032. https://doi.org/10.1093/femsle/fny032
55. Ibañez MI, Cabello P, Luque-Almagro VM, Saez LP, Olaya A, Sanchez de Medina V et al
(2017) Quantitative proteomic analysis of Pseudomonas pseudoalcaligenes CECT5344 in
response to industrial cyanide-containing wastewaters using Liquid Chromatography-Mass
Spectrometry/Mass Spectrometry (LC-MS/MS). PLoS One 12(3):e0172908. https://doi.org/
10.1371/journal.pone.0172908
56. Kumar SV, Menon S, Agarwal H, Gopalakrishnan D (2017) Characterization and optimization
of bacterium isolated from soil samples for the production of siderophores. Resour Effic
Technol 3(4):434–439. https://doi.org/10.1016/j.reffit.2017.04.004
57. Sandmann G (2015) Carotenoids of biotechnological importance. Adv Biochem Eng
Biotechnol 148:449–467. https://doi.org/10.1007/10_2014_277
58. Sathasivam R, Ki J-S (2018) A review of the biological activities of microalgal carotenoids
and their potential use in healthcare and cosmetic industries. Mar Drugs 16(26):19. https://doi.
org/10.3390/md16010026
59. Avalos J, Pardo-Medina J, Parra-Rivero O, Ruger-Herreros M, Rodríguez-Ortiz R, HorneroMéndez D, Limón MC (2017) Carotenoid biosynthesis in fusarium. J Fungi 3:39. https://doi.
org/10.3390/jof3030039
Metabolites Produced by Alkaliphiles with Potential Biotechnological. . .
189