Adv Polym Sci (2013) 262: 39–60
DOI: 10.1007/12_2013_254
© Springer-Verlag Berlin Heidelberg 2013
Published online: 6 November 2013
Synthetic Glycopolymers: Some Recent
Developments
Qiang Zhang and David M. Haddleton
Abstract Glycopolymers are synthetic macromolecules containing sugar moieties.
They have shown promise in biorelated applications and the number of synthetic
approaches for making these molecules is expanding rapidly. This field benefits
from the rapid development of synthetic polymer chemistry, which has seen
dramatic progress in the synthesis of functional glycopolymers. Strategies
employed in glycopolymer synthesis have been generally carried out as either
direct polymerization of glycomonomers or post-glycosylation of pre-formed
polymers. This contribution is a short overview of some of the recent developments
and will hopefully direct the reader to many papers of interest.
Keywords Glycopolymer Á Living radical polymerization Á Molecular recognition Á
Polymerization
Contents
1 Novel Strategies in the Direct Polymerization of Glycomonomers . . . . . . . . . . . . . . . . . . . . . . . . 40
1.1 Ring-Opening Polymerization . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 40
1.2 Copper-Mediated Living Radical Polymerization . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41
1.3 Reversible Addition-Fragmentation Chain Transfer Polymerization . . . . . . . . . . . . . . . . 46
The authors declare the following competing financial interests: D. M. Haddleton is a Director of
Warwick Effect Polymers Ltd.
Q. Zhang
Department of Chemistry, University of Warwick, CV4 7AL Coventry, UK
D.M. Haddleton (*)
Department of Chemistry, University of Warwick, CV4 7AL Coventry, UK
Monash Institute of Pharmaceutical Sciences, 381 Royal Parade, Parkville, Victoria 3052,
Australia
e-mail: D.M.Haddleton@warwick.ac.uk
DOI: 10.1007/12_2013_254
© Springer-Verlag Berlin Heidelberg 2013
Published online: 6 November 2013
Synthetic Glycopolymers: Some Recent
Developments
Qiang Zhang and David M. Haddleton
Abstract Glycopolymers are synthetic macromolecules containing sugar moieties.
They have shown promise in biorelated applications and the number of synthetic
approaches for making these molecules is expanding rapidly. This field benefits
from the rapid development of synthetic polymer chemistry, which has seen
dramatic progress in the synthesis of functional glycopolymers. Strategies
employed in glycopolymer synthesis have been generally carried out as either
direct polymerization of glycomonomers or post-glycosylation of pre-formed
polymers. This contribution is a short overview of some of the recent developments
and will hopefully direct the reader to many papers of interest.
Keywords Glycopolymer Á Living radical polymerization Á Molecular recognition Á
Polymerization
Contents
1 Novel Strategies in the Direct Polymerization of Glycomonomers . . . . . . . . . . . . . . . . . . . . . . . . 40
1.1 Ring-Opening Polymerization . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 40
1.2 Copper-Mediated Living Radical Polymerization . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41
1.3 Reversible Addition-Fragmentation Chain Transfer Polymerization . . . . . . . . . . . . . . . . 46
The authors declare the following competing financial interests: D. M. Haddleton is a Director of
Warwick Effect Polymers Ltd.
Q. Zhang
Department of Chemistry, University of Warwick, CV4 7AL Coventry, UK
D.M. Haddleton (*)
Department of Chemistry, University of Warwick, CV4 7AL Coventry, UK
Monash Institute of Pharmaceutical Sciences, 381 Royal Parade, Parkville, Victoria 3052,
Australia
e-mail: D.M.Haddleton@warwick.ac.uk