151
9
References
Anarat-Cappillino G, Sattely ES (2014) The chemical logic of plant natural product biosynthesis. Curr Opin
Plant Biol 19:51–58. https://doi.org/10.1016/j.pbi.2014.03.007
Barnaba C, Gentry K, Sumangala N, Ramamoorthy A (2017) The catalytic function of cytochrome P450 is
entwined with its membrane-bound nature. F1000Res 6:662. https://doi.org/10.12688/f1000research.11015.1
Bassard JE, Moller BL, Laursen T (2017) Assembly of dynamic P450-mediated metabolons-order versus
chaos. Curr Mol Biol Rep 3:37–51. https://doi.org/10.1007/s40610-017-0053-y
Boke H, Ozhuner E, Turktas M, Parmaksiz I, Ozcan S, Unver T (2015) Regulation of the alkaloid biosynthesis
by miRNA in opium poppy. Plant Biotechnol J 13:409–420. https://doi.org/10.1111/pbi.12346
Boughton AJ, Hoover K, Felton GW (2005) Methyl jasmonate application induces increased densities of
glandular trichomes on tomato, Lycopersicon esculentum. J Chem Ecol 31:2211–2216. https://doi.
org/10.1007/s10886-005-6228-7
Chezem WR, Clay NK (2016) Regulation of plant secondary metabolism and associated specialized cell
development by MYBs and bHLHs. Phytochemistry 131:26–43. https://doi.org/10.1016/j.phytochem.2016.08.006
Dewey RE, Xie J (2013) Molecular genetics of alkaloid biosynthesis in Nicotiana tabacum. Phytochemistry
94:10–27. https://doi.org/10.1016/j.phytochem.2013.06.002
Dewick PM (2002) The biosynthesis of C5–C25 terpenoid compounds. Nat Prod Rep 19:181–222. https://
doi.org/10.1039/b002685i
Doblas VG et al (2013) The SUD1 gene encodes a putative E3 ubiquitin ligase and is a positive regulator of
3-hydroxy-3-methylglutaryl coenzyme a reductase activity in Arabidopsis. Plant Cell 25:728–743.
https://doi.org/10.1105/tpc.112.108696
Fenske MP, Imaizumi T (2016) Circadian rhythms in floral scent emission. Front Plant Sci 7:462. https://doi.
org/10.3389/fpls.2016.00462
Gimenez-Ibanez S, Boter M, Solano R (2015) Novel players fine-tune plant trade-offs. Essays Biochem
58:83–100. https://doi.org/10.1042/bse0580083
Goodspeed D, Chehab EW, Min-Venditti A, Braam J, Covington MF (2012) Arabidopsis synchronizes
jasmonate- mediated defense with insect circadian behavior. Proc Natl Acad Sci U S A 109:4674–4677.
https://doi.org/10.1073/pnas.1116368109
Groves JT (2015) Cytochrome P450 enzymes: understanding the biochemical hieroglyphs [version 1; referees: 3 approved]. F1000Research, (F1000 Faculty Rev):178 (doi: 1012688/f1000research63141) 4
(F1000 Faculty Rev) (doi: 10. 12688/f1000research. 6314. 1)
Havko NE, Major IT, Jewell JB, Attaran E, Browse J, Howe GA (2016) Control of carbon assimilation and
partitioning by jasmonate: an accounting of growth-defense tradeoffs. Plants (Basel) 5. https://doi.
org/10.3390/plants5010007
Hudgins JW, Franceschi VR (2004) Methyl jasmonate-induced ethylene production is responsible for conifer phloem defense responses and reprogramming of stem cambial zone for traumatic resin duct
formation. Plant Physiol 135:2134–2149. https://doi.org/10.1104/pp.103.037929
Huot B, Yao J, Montgomery BL, He SY (2014) Growth-defense tradeoffs in plants: a balancing act to optimize fitness. Mol Plant 7:1267–1287. https://doi.org/10.1093/mp/ssu049
Take-Home Messages
5 Building blocks for secondary metabolites are mainly derived from photosynthesis, glycolysis, TCA cycle and amino acids.
5 Once the scaffold is formed, tailoring enzymes modify the structures by adding
or removing of groups, oxidation reaction, desaturation and cyclization. Often
also glucosylation occurs.
5 Plants usually contain many different secondary metabolites, but some species
contain very specific groups of secondary metabolites.
5 The mixture of compounds varies between different cells, tissues and developmental stages and can be influenced by external stressors.
5 Jasmonic acid is a major integrator to balance growth-defence trade-off.
References
9
References
Anarat-Cappillino G, Sattely ES (2014) The chemical logic of plant natural product biosynthesis. Curr Opin
Plant Biol 19:51–58. https://doi.org/10.1016/j.pbi.2014.03.007
Barnaba C, Gentry K, Sumangala N, Ramamoorthy A (2017) The catalytic function of cytochrome P450 is
entwined with its membrane-bound nature. F1000Res 6:662. https://doi.org/10.12688/f1000research.11015.1
Bassard JE, Moller BL, Laursen T (2017) Assembly of dynamic P450-mediated metabolons-order versus
chaos. Curr Mol Biol Rep 3:37–51. https://doi.org/10.1007/s40610-017-0053-y
Boke H, Ozhuner E, Turktas M, Parmaksiz I, Ozcan S, Unver T (2015) Regulation of the alkaloid biosynthesis
by miRNA in opium poppy. Plant Biotechnol J 13:409–420. https://doi.org/10.1111/pbi.12346
Boughton AJ, Hoover K, Felton GW (2005) Methyl jasmonate application induces increased densities of
glandular trichomes on tomato, Lycopersicon esculentum. J Chem Ecol 31:2211–2216. https://doi.
org/10.1007/s10886-005-6228-7
Chezem WR, Clay NK (2016) Regulation of plant secondary metabolism and associated specialized cell
development by MYBs and bHLHs. Phytochemistry 131:26–43. https://doi.org/10.1016/j.phytochem.2016.08.006
Dewey RE, Xie J (2013) Molecular genetics of alkaloid biosynthesis in Nicotiana tabacum. Phytochemistry
94:10–27. https://doi.org/10.1016/j.phytochem.2013.06.002
Dewick PM (2002) The biosynthesis of C5–C25 terpenoid compounds. Nat Prod Rep 19:181–222. https://
doi.org/10.1039/b002685i
Doblas VG et al (2013) The SUD1 gene encodes a putative E3 ubiquitin ligase and is a positive regulator of
3-hydroxy-3-methylglutaryl coenzyme a reductase activity in Arabidopsis. Plant Cell 25:728–743.
https://doi.org/10.1105/tpc.112.108696
Fenske MP, Imaizumi T (2016) Circadian rhythms in floral scent emission. Front Plant Sci 7:462. https://doi.
org/10.3389/fpls.2016.00462
Gimenez-Ibanez S, Boter M, Solano R (2015) Novel players fine-tune plant trade-offs. Essays Biochem
58:83–100. https://doi.org/10.1042/bse0580083
Goodspeed D, Chehab EW, Min-Venditti A, Braam J, Covington MF (2012) Arabidopsis synchronizes
jasmonate- mediated defense with insect circadian behavior. Proc Natl Acad Sci U S A 109:4674–4677.
https://doi.org/10.1073/pnas.1116368109
Groves JT (2015) Cytochrome P450 enzymes: understanding the biochemical hieroglyphs [version 1; referees: 3 approved]. F1000Research, (F1000 Faculty Rev):178 (doi: 1012688/f1000research63141) 4
(F1000 Faculty Rev) (doi: 10. 12688/f1000research. 6314. 1)
Havko NE, Major IT, Jewell JB, Attaran E, Browse J, Howe GA (2016) Control of carbon assimilation and
partitioning by jasmonate: an accounting of growth-defense tradeoffs. Plants (Basel) 5. https://doi.
org/10.3390/plants5010007
Hudgins JW, Franceschi VR (2004) Methyl jasmonate-induced ethylene production is responsible for conifer phloem defense responses and reprogramming of stem cambial zone for traumatic resin duct
formation. Plant Physiol 135:2134–2149. https://doi.org/10.1104/pp.103.037929
Huot B, Yao J, Montgomery BL, He SY (2014) Growth-defense tradeoffs in plants: a balancing act to optimize fitness. Mol Plant 7:1267–1287. https://doi.org/10.1093/mp/ssu049
Take-Home Messages
5 Building blocks for secondary metabolites are mainly derived from photosynthesis, glycolysis, TCA cycle and amino acids.
5 Once the scaffold is formed, tailoring enzymes modify the structures by adding
or removing of groups, oxidation reaction, desaturation and cyclization. Often
also glucosylation occurs.
5 Plants usually contain many different secondary metabolites, but some species
contain very specific groups of secondary metabolites.
5 The mixture of compounds varies between different cells, tissues and developmental stages and can be influenced by external stressors.
5 Jasmonic acid is a major integrator to balance growth-defence trade-off.
References