Ning, Z., Seebun, D., Hawley, B., Chang, C.-K., Figeys, D. (2013) From cells to peptides: “One-stop” integrated
proteomic processing using amphipols. J. Proteome Res. 12:1512–1519.
Perlmutter, J.D., Popot, J.-L., Sachs, J.N. (2014) Molecular dynamics simulations of a membrane protein/amphipol
complex. J. Membr. Biol. 247:883–895.
Popot, J.-L., Berry, E.A., Charvolin, D., Creuzenet, C., Ebel, C., Engelman, D.M., Flötenmeyer, M., Giusti, F., Gohon,
Y., Hervé, P., Hong, Q., Lakey, J.H., Leonard, K., Shuman, H.A., Timmins, P., Warschawski, D.E., Zito, F.,
Zoonens, M., Pucci, B., Tribet, C. (2003) Amphipols: polymeric surfactants for membrane biology research. Cell.
Mol. Life Sci. 60:1559–1574.
Popot, J.-L., Althoff, T., Bagnard, D., Baneres, J.L., Bazzacco, P., Billon-Denis, E., Catoire, L.J., Champeil, P.,
Charvolin, D., Cocco, M.J., Cremel, G., Dahmane, T., de la Maza, L.M., Ebel, C., Gabel, F., Giusti, F., Gohon,
Y., Goormaghtigh, E., Guittet, E., Kleinschmidt, J.H., Kuhlbrandt, W., Le Bon, C., Martinez, K.L., Picard, M., Pucci,
B., Sachs, J.N., Tribet, C., van Heijenoort, C., Wien, F., Zito, F., Zoonens, M. (2011) Amphipols from A to Z. Annu.
Rev. Biophys. 40:379–408.
Pringle, S.D., Giles, K., Wildgoose, J.L., Williams, J.P., Slade, S.E., Thalassinos, K., Bateman, R.H., Bowers, M.T.,
Scrivens, J.H. (2007) An investigation of the mobility separation of some peptide and protein ions using a new hybrid
quadrupole/travelling wave IMS/oa-ToF instrument. Int. J. Mass Spectrom. 261:1–12.
Rajabi, K., Ashcroft, A.E., Radford, S.E. (2015) Mass spectrometric methods to analyze the structural organization of
macromolecular complexes. Methods 89:13–21.
Reading, E., Liko, I., Allison, T.M., Benesch, J.L.P., Laganowsky, A., Robinson, C.V. (2015) The role of the detergent
micelle in preserving the structure of membrane proteins in the gas phase. Angew. Chem. Int. Ed. 54:4577–4581
Rouse, S.L., Marcoux, J., Robinson, C.V., Sansom, M.S.P. (2013) Dodecylmaltoside protects membrane proteins in
vacuo. Biophys. J. 105:648–656.
Ruotolo, B.T., Benesch, J.L.P., Sandercock, A.M., Hyung, S.J., Robinson, C.V. (2008) Ion mobility-mass spectrometry
analysis of large protein complexes. Nat. Protoc. 3:1139–1152.
Ruotolo, B.T., Giles, K., Campuzano, I., Sandercock, A.M., Bateman, R.H., Robinson, C.V. (2005) Evidence for
macromolecular protein rings in the absence of bulk water. Science 310:1658–1661.
Ruotolo, B.T., Robinson, C.V. (2006) Aspects of native proteins are retained in vacuum. Curr. Opin. Chem. Biol.
10:402–408.
Schiffrin, B., Calabrese, A.N., Devine, P.W., Harris, S.A., Ashcroft, A.E., Brockwell, D.J., Radford, S.E. (2016) Skp is a
multivalent chaperone of outer-membrane proteins. Nat. Struct. Mol. Biol. 23:786–793.
Sharma, K.S., Durand, G., Gabel, F., Bazzacco, P., Le Bon, C., Billon-Denis, E., Catoire, L.J., Popot, J.-L., Ebel, C.,
Pucci, B. (2012) Non-ionic amphiphilic homopolymers: Synthesis, solution properties, and biochemical validation.
Langmuir 28:4625–4639.
Shvartsburg, A.A., Jarrold, M.F. (1996) An exact hard-spheres scattering model for the mobilities of polyatomic ions.
Chem. Phys. Lett. 261:86–91.
Smith, D.P., Knapman, T.W., Campuzano, I., Malham, R.W., Berryman, J.T., Radford, S.E., Ashcroft, A.E. (2009)
Deciphering drift time measurements from travelling wave ion mobility spectrometry-mass spectrometry studies.
Eur. J. Mass Spectrom. 15:113–130.
Sobott, F., Hernandez, H., McCammon, M.G., Tito, M.A., Robinson, C.V. (2002) A tandem mass spectrometer for
improved transmission and analysis of large macromolecular assemblies. Anal. Chem. 74:1402–1407.
Stroebel, D., Choquet, Y., Popot, J.-L., Picot, D. (2003) An atypical haem in the cytochrome b 6 f complex. Nature
426:413–418.
Titeca, K., Van Quickelberghe, E., Samyn, N., De Sutter, D., Verhee, A., Gevaert, K., Tavernier, J., Eyckerman S. (2017)
Analyzing trapped protein complexes by Virotrap and SFINX. Nat. Protoc. 12:881–898.
Tribet, C., Audebert, R., Popot, J.-L. (1996) Amphipols: polymers that keep membrane proteins soluble in aqueous
solutions. Proc. Natl. Acad. Sci. USA 93:15047–15050.
van Dyck, J.F., Konijnenberg, A., Sobott, F. (2017) Native mass spectrometry for the characterization of structure and
interactions of membrane proteins. Meth. Mol. Biol. 1635:205–232.
Watkinson, T.G., Calabrese, A.N., Ault, J.R., Radford, S.E., Ashcroft, A.E. (2017) FPOP-LC-MS/MS suggests
differences in interaction sites of amphipols and detergents with outer membrane proteins. J. Am. Soc. Mass
Spectrom. 28:50–55.
Watkinson, T.G., Calabrese, A.N., Giusti, F., Zoonens, M., Radford, S.E., Ashcroft, A.E. (2015) Systematic analysis of
the use of amphipathic polymers for studies of outer membrane proteins using mass spectrometry. Int. J. Mass
Spectrom. 391:54–61.
Weidner, S.M., Trimpin, S. (2010) Mass spectrometry of synthetic polymers. Anal. Chem. 82:4811–4829.
Whitelegge, J.P. (2013) Integral membrane proteins and bilayer proteomics. Anal. Chem. 85:2558–2568.
Wilm, M.S., Mann, M. (1994) Electrospray and Taylor-Cone theory, Dole’s beam of macromolecules at last? Int. J. Mass
Spectrom. Ion Processes 136:167–180.
References
657
proteomic processing using amphipols. J. Proteome Res. 12:1512–1519.
Perlmutter, J.D., Popot, J.-L., Sachs, J.N. (2014) Molecular dynamics simulations of a membrane protein/amphipol
complex. J. Membr. Biol. 247:883–895.
Popot, J.-L., Berry, E.A., Charvolin, D., Creuzenet, C., Ebel, C., Engelman, D.M., Flötenmeyer, M., Giusti, F., Gohon,
Y., Hervé, P., Hong, Q., Lakey, J.H., Leonard, K., Shuman, H.A., Timmins, P., Warschawski, D.E., Zito, F.,
Zoonens, M., Pucci, B., Tribet, C. (2003) Amphipols: polymeric surfactants for membrane biology research. Cell.
Mol. Life Sci. 60:1559–1574.
Popot, J.-L., Althoff, T., Bagnard, D., Baneres, J.L., Bazzacco, P., Billon-Denis, E., Catoire, L.J., Champeil, P.,
Charvolin, D., Cocco, M.J., Cremel, G., Dahmane, T., de la Maza, L.M., Ebel, C., Gabel, F., Giusti, F., Gohon,
Y., Goormaghtigh, E., Guittet, E., Kleinschmidt, J.H., Kuhlbrandt, W., Le Bon, C., Martinez, K.L., Picard, M., Pucci,
B., Sachs, J.N., Tribet, C., van Heijenoort, C., Wien, F., Zito, F., Zoonens, M. (2011) Amphipols from A to Z. Annu.
Rev. Biophys. 40:379–408.
Pringle, S.D., Giles, K., Wildgoose, J.L., Williams, J.P., Slade, S.E., Thalassinos, K., Bateman, R.H., Bowers, M.T.,
Scrivens, J.H. (2007) An investigation of the mobility separation of some peptide and protein ions using a new hybrid
quadrupole/travelling wave IMS/oa-ToF instrument. Int. J. Mass Spectrom. 261:1–12.
Rajabi, K., Ashcroft, A.E., Radford, S.E. (2015) Mass spectrometric methods to analyze the structural organization of
macromolecular complexes. Methods 89:13–21.
Reading, E., Liko, I., Allison, T.M., Benesch, J.L.P., Laganowsky, A., Robinson, C.V. (2015) The role of the detergent
micelle in preserving the structure of membrane proteins in the gas phase. Angew. Chem. Int. Ed. 54:4577–4581
Rouse, S.L., Marcoux, J., Robinson, C.V., Sansom, M.S.P. (2013) Dodecylmaltoside protects membrane proteins in
vacuo. Biophys. J. 105:648–656.
Ruotolo, B.T., Benesch, J.L.P., Sandercock, A.M., Hyung, S.J., Robinson, C.V. (2008) Ion mobility-mass spectrometry
analysis of large protein complexes. Nat. Protoc. 3:1139–1152.
Ruotolo, B.T., Giles, K., Campuzano, I., Sandercock, A.M., Bateman, R.H., Robinson, C.V. (2005) Evidence for
macromolecular protein rings in the absence of bulk water. Science 310:1658–1661.
Ruotolo, B.T., Robinson, C.V. (2006) Aspects of native proteins are retained in vacuum. Curr. Opin. Chem. Biol.
10:402–408.
Schiffrin, B., Calabrese, A.N., Devine, P.W., Harris, S.A., Ashcroft, A.E., Brockwell, D.J., Radford, S.E. (2016) Skp is a
multivalent chaperone of outer-membrane proteins. Nat. Struct. Mol. Biol. 23:786–793.
Sharma, K.S., Durand, G., Gabel, F., Bazzacco, P., Le Bon, C., Billon-Denis, E., Catoire, L.J., Popot, J.-L., Ebel, C.,
Pucci, B. (2012) Non-ionic amphiphilic homopolymers: Synthesis, solution properties, and biochemical validation.
Langmuir 28:4625–4639.
Shvartsburg, A.A., Jarrold, M.F. (1996) An exact hard-spheres scattering model for the mobilities of polyatomic ions.
Chem. Phys. Lett. 261:86–91.
Smith, D.P., Knapman, T.W., Campuzano, I., Malham, R.W., Berryman, J.T., Radford, S.E., Ashcroft, A.E. (2009)
Deciphering drift time measurements from travelling wave ion mobility spectrometry-mass spectrometry studies.
Eur. J. Mass Spectrom. 15:113–130.
Sobott, F., Hernandez, H., McCammon, M.G., Tito, M.A., Robinson, C.V. (2002) A tandem mass spectrometer for
improved transmission and analysis of large macromolecular assemblies. Anal. Chem. 74:1402–1407.
Stroebel, D., Choquet, Y., Popot, J.-L., Picot, D. (2003) An atypical haem in the cytochrome b 6 f complex. Nature
426:413–418.
Titeca, K., Van Quickelberghe, E., Samyn, N., De Sutter, D., Verhee, A., Gevaert, K., Tavernier, J., Eyckerman S. (2017)
Analyzing trapped protein complexes by Virotrap and SFINX. Nat. Protoc. 12:881–898.
Tribet, C., Audebert, R., Popot, J.-L. (1996) Amphipols: polymers that keep membrane proteins soluble in aqueous
solutions. Proc. Natl. Acad. Sci. USA 93:15047–15050.
van Dyck, J.F., Konijnenberg, A., Sobott, F. (2017) Native mass spectrometry for the characterization of structure and
interactions of membrane proteins. Meth. Mol. Biol. 1635:205–232.
Watkinson, T.G., Calabrese, A.N., Ault, J.R., Radford, S.E., Ashcroft, A.E. (2017) FPOP-LC-MS/MS suggests
differences in interaction sites of amphipols and detergents with outer membrane proteins. J. Am. Soc. Mass
Spectrom. 28:50–55.
Watkinson, T.G., Calabrese, A.N., Giusti, F., Zoonens, M., Radford, S.E., Ashcroft, A.E. (2015) Systematic analysis of
the use of amphipathic polymers for studies of outer membrane proteins using mass spectrometry. Int. J. Mass
Spectrom. 391:54–61.
Weidner, S.M., Trimpin, S. (2010) Mass spectrometry of synthetic polymers. Anal. Chem. 82:4811–4829.
Whitelegge, J.P. (2013) Integral membrane proteins and bilayer proteomics. Anal. Chem. 85:2558–2568.
Wilm, M.S., Mann, M. (1994) Electrospray and Taylor-Cone theory, Dole’s beam of macromolecules at last? Int. J. Mass
Spectrom. Ion Processes 136:167–180.
References
657