Prata, C., Giusti, F., Gohon, Y., Pucci, B., Popot, J.-L., Tribet, C. (2001) Non-ionic amphiphilic polymers derived from
tris(hydroxymethyl)-acrylamidomethane keep membrane proteins soluble and native in the absence of detergent.
Biopolymers 56:77–84.
Qi, L., Gao, X. (2008) Quantum dot-amphipol nanocomplex for intracellular delivery and real-time imaging of siRNA.
ACS Nano 2:1403–1410.
Rahmeh, R., Damian, M., Cottet, M., Orcel, H., Mendre, C., Durroux, T., Sharma, K.S., Durand, G., Pucci, B., Trinquet,
E., Zwier, J.M., Deupi, X., Bron, P., J.-L. B., Mouillac, B., Granier, S. (2012) Structural insights into biased G
protein-coupled receptor signaling revealed by fluorescence spectroscopy. Proc. Natl. Acad. Sci. USA
109:6733–6738.
Rajesh, S., Knowles, T.J., Overduin, M. (2011) Production of membrane proteins without cells or detergents. New
Biotechnol. 28:250–254.
Rehan, S., Paavilainen, V.O., Jaakola, V.P. (2017) Functional reconstitution of human equilibrative nucleoside
transporter-1 into styrene maleic acid co-polymer lipid particles. Biochim. Biophys. Acta 1859:1059–1065.
Reich-Slotky, R., Panagiotidis, C., Reyes, M., Shuman, H.A. (2000) The detergent-soluble maltose transporter is
activated by maltose binding protein and verapamil. J. Bact. 182:993–1000.
Renault, M. (2008) Etudes structurales et dynamiques de la protéine membranaire KpOmpA par RMN en phase liquide et
solide. Thèse de Doctorat, Université Paul Sabatier, Toulouse, 180 p.
Renner, C., Kessler, B., Oesterhelt, D. (2005) Lipid composition of integral purple membrane by
1
H and
31
P NMR.
J. Lipid Res. 46:1755–1764.
Ritchie, T.K., Grinkova, Y.V., Bayburt, T.H., Denisov, I.G., Zolnerciks, J.K., Atkins, W.M., Sligar, S.G. (2009)
Reconstitution of membrane proteins in phospholipid bilayer nanodiscs. Meth. Enzymol. 464:211–231.
Rosenbaum, D.M., Cherezov, V., Hanson, M.A., Rasmussen, S.G., Thian, F.S., Kobilka, T.S., Choi, H.J., Yao, X.J.,
Weis, W.I., Stevens, R.C., Kobilka, B.K. (2007) GPCR engineering yields high-resolution structural insights into β 2 -
adrenergic receptor function. Science 318:1266–1273.
Sahu, I.D., McCarrick, R.M., Troxel, K.R., Zhang, R., Smith, H.J., Dunagan, M.M., Swartz, M.S., Rajan, P.V., Kroncke,
B.M., Sanders, C.R., Lorigan, G.A. (2013) DEER EPR measurements for membrane protein structures via bifunctional spin labels and lipodisq nanoparticles. Biochemistry 52:6627–6632.
Sebai, S., Cribier, S., Karimi, A., Massotte, D., Tribet, T. (2010) Permeabilisation of lipid membranes and cells by a lightresponsive copolymer. Langmuir 26:14135–14141.
Sebai, S., Milioni, D., Walrant, A., Alves, I., Sagan, S., Huin, C., Auvray, L., Massotte, D., Cribier, S., Tribet, C. (2012)
Photocontrol of the translocation of molecules, peptides, and quantum dots through cell and lipid membranes doped
with azobenzene copolymers. Angew. Chem. Int. Ed. 51:2132–2136.
Shao, J., Fu, Z., Ji, Y., Guan, X., Guo, S., Ding, Z., Yang, X., Cong, Y., Shen, Y. (2016) Leucine zipper-EF-hand
containing transmembrane protein 1 (LETM1) forms a Ca
2+ /H
+ antiporter. Sci. Rep. 6:34174.
Sharma, K.S., Durand, G., Gabel, F., Bazzacco, P., Le Bon, C., Billon-Denis, E., Catoire, L.J., Popot, J.-L., Ebel, C.,
Pucci, B. (2012) Non-ionic amphiphilic homopolymers: Synthesis, solution properties, and biochemical validation.
Langmuir 28:4625–4639.
Sharma, K.S., Durand, G., Giusti, F., Olivier, B., Fabiano, A.-S., Bazzacco, P., Dahmane, T., Ebel, C., Popot, J.-L.,
Pucci, B. (2008) Glucose-based amphiphilic telomers designed to keep membrane proteins soluble in aqueous
solutions: synthesis and physico-chemical characterization. Langmuir 24:13581–13590.
Shen, P.S., Yang, X., DeCaen, P.G., Liu, X., Bulkley, D., Clapham, D.E., Cao, E. (2016) The structure of the Polycystic
Kidney Disease channel PKD2 in lipid nanodiscs. Cell 167:763–773.e711.
Shinzawa-Itoh, K., Shimomura, H., Yanagisawa, S., Shimada, S., Takahashi, R., Oosaki, M., Ogura, T., Tsukihara,
T. (2016) Purification of active respiratory supercomplex from bovine heart mitochondria enables functional studies.
J. Biol. Chem. 291:4178–4184.
Skaar, K., Korza, H.J., Tarry, M., Sekyrova, P., Högbom, M. (2015) Expression and subcellular distribution of
GFP-tagged human tetraspanin proteins in Saccharomyces cerevisiae. PLoS One 10:e0134041.
Smirnova, I.A., Sjöstrand, D., Li, F., Björck, M., Schäfer, J., Östbye, H., Högbom, M., von Ballmoos, C., Lander, G.,
Ädelroth, P., Brzezinski, P. (2016) Isolation of yeast Complex IV in native lipid nanodiscs. Biochim. Biophys. Acta,
1858:2984–2992.
Sólyom, Z., Ma, P., Schwarten, M., Bosco, M.I., Polidori, A., Durand, G., Willbold, D., Brutscher, B. (2015) The
disordered region of the HCV protein NS5A: conformational dynamics, SH3 binding, and phosphorylation. Biophys.
J. 109:1483–1496.
Sonntag, Y., Musgaard, M., Olesen, C., Schiøtt, B., Møller, J.V., Nissen, P., Thøgersen, L. (2011) Mutual adaptation of a
membrane protein and its lipid bilayer during conformational changes. Nat. Commun. 2:304.
Sousa, J.S., Mills, D.J., Vonck, J., Kühlbrandt, W. (2016) Functional asymmetry and electron flow in the bovine
respirasome. eLIFE 5:e21290.
330
5 Formation and Properties of Membrane Protein/Amphipol Complexes
tris(hydroxymethyl)-acrylamidomethane keep membrane proteins soluble and native in the absence of detergent.
Biopolymers 56:77–84.
Qi, L., Gao, X. (2008) Quantum dot-amphipol nanocomplex for intracellular delivery and real-time imaging of siRNA.
ACS Nano 2:1403–1410.
Rahmeh, R., Damian, M., Cottet, M., Orcel, H., Mendre, C., Durroux, T., Sharma, K.S., Durand, G., Pucci, B., Trinquet,
E., Zwier, J.M., Deupi, X., Bron, P., J.-L. B., Mouillac, B., Granier, S. (2012) Structural insights into biased G
protein-coupled receptor signaling revealed by fluorescence spectroscopy. Proc. Natl. Acad. Sci. USA
109:6733–6738.
Rajesh, S., Knowles, T.J., Overduin, M. (2011) Production of membrane proteins without cells or detergents. New
Biotechnol. 28:250–254.
Rehan, S., Paavilainen, V.O., Jaakola, V.P. (2017) Functional reconstitution of human equilibrative nucleoside
transporter-1 into styrene maleic acid co-polymer lipid particles. Biochim. Biophys. Acta 1859:1059–1065.
Reich-Slotky, R., Panagiotidis, C., Reyes, M., Shuman, H.A. (2000) The detergent-soluble maltose transporter is
activated by maltose binding protein and verapamil. J. Bact. 182:993–1000.
Renault, M. (2008) Etudes structurales et dynamiques de la protéine membranaire KpOmpA par RMN en phase liquide et
solide. Thèse de Doctorat, Université Paul Sabatier, Toulouse, 180 p.
Renner, C., Kessler, B., Oesterhelt, D. (2005) Lipid composition of integral purple membrane by
1
H and
31
P NMR.
J. Lipid Res. 46:1755–1764.
Ritchie, T.K., Grinkova, Y.V., Bayburt, T.H., Denisov, I.G., Zolnerciks, J.K., Atkins, W.M., Sligar, S.G. (2009)
Reconstitution of membrane proteins in phospholipid bilayer nanodiscs. Meth. Enzymol. 464:211–231.
Rosenbaum, D.M., Cherezov, V., Hanson, M.A., Rasmussen, S.G., Thian, F.S., Kobilka, T.S., Choi, H.J., Yao, X.J.,
Weis, W.I., Stevens, R.C., Kobilka, B.K. (2007) GPCR engineering yields high-resolution structural insights into β 2 -
adrenergic receptor function. Science 318:1266–1273.
Sahu, I.D., McCarrick, R.M., Troxel, K.R., Zhang, R., Smith, H.J., Dunagan, M.M., Swartz, M.S., Rajan, P.V., Kroncke,
B.M., Sanders, C.R., Lorigan, G.A. (2013) DEER EPR measurements for membrane protein structures via bifunctional spin labels and lipodisq nanoparticles. Biochemistry 52:6627–6632.
Sebai, S., Cribier, S., Karimi, A., Massotte, D., Tribet, T. (2010) Permeabilisation of lipid membranes and cells by a lightresponsive copolymer. Langmuir 26:14135–14141.
Sebai, S., Milioni, D., Walrant, A., Alves, I., Sagan, S., Huin, C., Auvray, L., Massotte, D., Cribier, S., Tribet, C. (2012)
Photocontrol of the translocation of molecules, peptides, and quantum dots through cell and lipid membranes doped
with azobenzene copolymers. Angew. Chem. Int. Ed. 51:2132–2136.
Shao, J., Fu, Z., Ji, Y., Guan, X., Guo, S., Ding, Z., Yang, X., Cong, Y., Shen, Y. (2016) Leucine zipper-EF-hand
containing transmembrane protein 1 (LETM1) forms a Ca
2+ /H
+ antiporter. Sci. Rep. 6:34174.
Sharma, K.S., Durand, G., Gabel, F., Bazzacco, P., Le Bon, C., Billon-Denis, E., Catoire, L.J., Popot, J.-L., Ebel, C.,
Pucci, B. (2012) Non-ionic amphiphilic homopolymers: Synthesis, solution properties, and biochemical validation.
Langmuir 28:4625–4639.
Sharma, K.S., Durand, G., Giusti, F., Olivier, B., Fabiano, A.-S., Bazzacco, P., Dahmane, T., Ebel, C., Popot, J.-L.,
Pucci, B. (2008) Glucose-based amphiphilic telomers designed to keep membrane proteins soluble in aqueous
solutions: synthesis and physico-chemical characterization. Langmuir 24:13581–13590.
Shen, P.S., Yang, X., DeCaen, P.G., Liu, X., Bulkley, D., Clapham, D.E., Cao, E. (2016) The structure of the Polycystic
Kidney Disease channel PKD2 in lipid nanodiscs. Cell 167:763–773.e711.
Shinzawa-Itoh, K., Shimomura, H., Yanagisawa, S., Shimada, S., Takahashi, R., Oosaki, M., Ogura, T., Tsukihara,
T. (2016) Purification of active respiratory supercomplex from bovine heart mitochondria enables functional studies.
J. Biol. Chem. 291:4178–4184.
Skaar, K., Korza, H.J., Tarry, M., Sekyrova, P., Högbom, M. (2015) Expression and subcellular distribution of
GFP-tagged human tetraspanin proteins in Saccharomyces cerevisiae. PLoS One 10:e0134041.
Smirnova, I.A., Sjöstrand, D., Li, F., Björck, M., Schäfer, J., Östbye, H., Högbom, M., von Ballmoos, C., Lander, G.,
Ädelroth, P., Brzezinski, P. (2016) Isolation of yeast Complex IV in native lipid nanodiscs. Biochim. Biophys. Acta,
1858:2984–2992.
Sólyom, Z., Ma, P., Schwarten, M., Bosco, M.I., Polidori, A., Durand, G., Willbold, D., Brutscher, B. (2015) The
disordered region of the HCV protein NS5A: conformational dynamics, SH3 binding, and phosphorylation. Biophys.
J. 109:1483–1496.
Sonntag, Y., Musgaard, M., Olesen, C., Schiøtt, B., Møller, J.V., Nissen, P., Thøgersen, L. (2011) Mutual adaptation of a
membrane protein and its lipid bilayer during conformational changes. Nat. Commun. 2:304.
Sousa, J.S., Mills, D.J., Vonck, J., Kühlbrandt, W. (2016) Functional asymmetry and electron flow in the bovine
respirasome. eLIFE 5:e21290.
330
5 Formation and Properties of Membrane Protein/Amphipol Complexes