10
18
26
34
42
Crystal phase
Sub transition
Pre transition
Gel phase
Riple phase
Fluid phase
Temperature [°C]
Main transition
Fig. 4.3 Phase transition of lipid membrane observed by DSC
Liposomes of dipalmitoyl phosphatidylcholine (DPPC) were prepared and their thermograph was
observed by DSC at scanning rate of 0.5
C/min
0
0.5
1.5
2.0
2.5
Lamellar distance
Ripple distance
135 Å
71 Å
67 Å
63 Å
Fluid phase
Ripple phase
Gel phase
5
10
15
20
25
30
35
40
45
50
T
e
m
p
e
r
a
tu
r
e
]
[
100
sin
2
1
−
×
A
λ
θ
Fig. 4.4 X-ray diffraction pattern of DPPC multi-lamellar liposomes
Multi-lamellar liposomes of dipalmitoyl phosphatidylcholine (DPPC) were prepared and X-ray
diffraction patterns at various temperatures were measured by SOR X-ray
62
4 Structure and Physical Properties of Biomembranes