References
1. Rogozhin SV, Davankov VA (1971) Ligand chromatography on asymmetric complex-forming
sorbents as a new method for resolution of racemates. J Chem Soc Chem Commun
1971:490–493
2. Okamoto Y, Ikai T (2008) Chiral HPLC for efficient resolution of enantiomers. Chem Soc Rev
37:2593–2608
3. Subramanian G (ed) (2007) Chiral separation techniques: a practical approach, 3rd edn. WileyVCH, Weinheim
4. Nakano T (2001) Optically active synthetic polymers as chiral stationary phases in HPLC.
J Chromatogr A 906:205–225
5. Yamamoto C, Okamoto Y (2004) Optically active polymers for chiral separation. Bull Chem
Soc Jpn 77:227–257
6. Chen XM, Yamamoto C, Okamoto Y (2007) Polysaccharide derivatives as useful chiral
stationary phases in high-performance liquid chromatography. Pure Appl Chem 79:1561–1573
7. Okamoto Y (2009) Chiral polymers for resolution of enantiomers. J Polym Sci A Polym Chem
47:1731–1739
8. Ikai T, Okamoto Y (2009) Structure control of polysaccharide derivatives for efficient separation of enantiomers by chromatorgaphy. Chem Rev 109:6077–6101
9. Okamoto Y, Hatada K (1986) Resolution of enantiomers by HPLC on optically active poly(triphenylmethyl methacrylate). J Liq Chromatogr 9:369–384
10. Yuki H, Hatada K, Kikuchi Y, Niinomi T (1968) Stereospecific polymerization of trityl
methacrylate. J Polym Sci B Polym Lett 6:753–755
11. Okamoto Y, Suzuki K, Ohta K, Hatada K, Yuki H (1979) Optically active poly(triphenylmethyl methacrylate) with one-handed helical conformation. J Am Chem Soc
101:4763–4765
12. Nakano T, Okamoto Y, Hatada K (1992) Asymmetric polymerization of triphenylmethyl
methacrylate leading to a one-handed helical polymer: mechanism of polymerization. J Am
Chem Soc 114:1318–1329
13. Okamoto Y, Mohri H, Hatada K (1988) Highly helix-sense-selective polymerization of
diphenyl-2-pyridylmethyl methacrylate. Chem Lett 17:1879–1882
14. Okamoto Y, Mohri H, Nakano T, Hatada K (1989) Stereomutation of optically active poly(diphenyl-2-pyridylmethyl methacrylate). J Am Chem Soc 111:5952–5954
15. Okamoto Y, Yashima E (1990) Asymmetric polymerization of methacrylates. Prog Polym Sci
15:263–298
16. Yuki H, Okamoto Y, Okamoto I (1980) Resolution of racemic compounds by optically active
poly(triphenylmethyl methacrylate). J Am Chem Soc 102:6356–6358
17. Okamoto Y, Okamoto I, Yuki H (1981) Chromatographic resolution of enantiomers having
aromatic group by optically active poly(triphenylmethyl methacrylate). Chem Lett
10:835–838
18. Okamoto Y, Honda S, Okamoto I, Yuki H, Murata S, Noyori R, Takaya H (1981) Novel
packing material for optical resolution: (+)-poly(triphenylmethyl methacrylate) coated on
macroporous silica gel. J Am Chem Soc 103:6971–6973
19. Okamoto Y, Mohri H, Hatada K (1989) Chromatographic optical resolution by optically active
poly(diphenyl-2-pyridylmethyl methacrylate) with a highly one-handed helical structure.
Polym J 21:439–445
20. Blaschke G (1980) Chromatographic resolution of racemates. Angew Chem Int Ed Engl
19:13–24
21. Morioka K, Suito Y, Isobe Y, Habaue S, Okamoto Y (2003) Synthesis and chiral recognition
ability of optically active poly{N-[R-α-methoxycarbonylbenzyl]-methacrylamide} with
various tacticities by radical polymerization using Lewis acids. J Polym Sci A Polym Chem
41:3354–3360
Helical Polymers for Efficient Enantiomer Separation
411
1. Rogozhin SV, Davankov VA (1971) Ligand chromatography on asymmetric complex-forming
sorbents as a new method for resolution of racemates. J Chem Soc Chem Commun
1971:490–493
2. Okamoto Y, Ikai T (2008) Chiral HPLC for efficient resolution of enantiomers. Chem Soc Rev
37:2593–2608
3. Subramanian G (ed) (2007) Chiral separation techniques: a practical approach, 3rd edn. WileyVCH, Weinheim
4. Nakano T (2001) Optically active synthetic polymers as chiral stationary phases in HPLC.
J Chromatogr A 906:205–225
5. Yamamoto C, Okamoto Y (2004) Optically active polymers for chiral separation. Bull Chem
Soc Jpn 77:227–257
6. Chen XM, Yamamoto C, Okamoto Y (2007) Polysaccharide derivatives as useful chiral
stationary phases in high-performance liquid chromatography. Pure Appl Chem 79:1561–1573
7. Okamoto Y (2009) Chiral polymers for resolution of enantiomers. J Polym Sci A Polym Chem
47:1731–1739
8. Ikai T, Okamoto Y (2009) Structure control of polysaccharide derivatives for efficient separation of enantiomers by chromatorgaphy. Chem Rev 109:6077–6101
9. Okamoto Y, Hatada K (1986) Resolution of enantiomers by HPLC on optically active poly(triphenylmethyl methacrylate). J Liq Chromatogr 9:369–384
10. Yuki H, Hatada K, Kikuchi Y, Niinomi T (1968) Stereospecific polymerization of trityl
methacrylate. J Polym Sci B Polym Lett 6:753–755
11. Okamoto Y, Suzuki K, Ohta K, Hatada K, Yuki H (1979) Optically active poly(triphenylmethyl methacrylate) with one-handed helical conformation. J Am Chem Soc
101:4763–4765
12. Nakano T, Okamoto Y, Hatada K (1992) Asymmetric polymerization of triphenylmethyl
methacrylate leading to a one-handed helical polymer: mechanism of polymerization. J Am
Chem Soc 114:1318–1329
13. Okamoto Y, Mohri H, Hatada K (1988) Highly helix-sense-selective polymerization of
diphenyl-2-pyridylmethyl methacrylate. Chem Lett 17:1879–1882
14. Okamoto Y, Mohri H, Nakano T, Hatada K (1989) Stereomutation of optically active poly(diphenyl-2-pyridylmethyl methacrylate). J Am Chem Soc 111:5952–5954
15. Okamoto Y, Yashima E (1990) Asymmetric polymerization of methacrylates. Prog Polym Sci
15:263–298
16. Yuki H, Okamoto Y, Okamoto I (1980) Resolution of racemic compounds by optically active
poly(triphenylmethyl methacrylate). J Am Chem Soc 102:6356–6358
17. Okamoto Y, Okamoto I, Yuki H (1981) Chromatographic resolution of enantiomers having
aromatic group by optically active poly(triphenylmethyl methacrylate). Chem Lett
10:835–838
18. Okamoto Y, Honda S, Okamoto I, Yuki H, Murata S, Noyori R, Takaya H (1981) Novel
packing material for optical resolution: (+)-poly(triphenylmethyl methacrylate) coated on
macroporous silica gel. J Am Chem Soc 103:6971–6973
19. Okamoto Y, Mohri H, Hatada K (1989) Chromatographic optical resolution by optically active
poly(diphenyl-2-pyridylmethyl methacrylate) with a highly one-handed helical structure.
Polym J 21:439–445
20. Blaschke G (1980) Chromatographic resolution of racemates. Angew Chem Int Ed Engl
19:13–24
21. Morioka K, Suito Y, Isobe Y, Habaue S, Okamoto Y (2003) Synthesis and chiral recognition
ability of optically active poly{N-[R-α-methoxycarbonylbenzyl]-methacrylamide} with
various tacticities by radical polymerization using Lewis acids. J Polym Sci A Polym Chem
41:3354–3360
Helical Polymers for Efficient Enantiomer Separation
411