1. Commercially available jelly-like medical liniments causing a cooling-down
effect when spread on the skin surface [11]. It is evident that this has no relation
at all to gel formation under frozen conditions.
2. The proteinaceous water-swollen coagulates that are formed upon low-positivetemperature chilling of blood plasma taken from the patients with rheumatoid
arthritis or some complex immune diseases [12, 13]. Since no freeze–thaw
treatment is applied to the precursor liquid in order to induce the formation of
such coagulates, the use of the term “cryogel” for this protein matter appears
unjustified.
Fig. 1 The number of publications (a) and citations (b) with keywords “cryogel” or “cryogels”
from 1980 to 1 November 2013 according to the ISI Web of Knowledge portal [3]
A Brief History of Polymeric Cryogels
3
effect when spread on the skin surface [11]. It is evident that this has no relation
at all to gel formation under frozen conditions.
2. The proteinaceous water-swollen coagulates that are formed upon low-positivetemperature chilling of blood plasma taken from the patients with rheumatoid
arthritis or some complex immune diseases [12, 13]. Since no freeze–thaw
treatment is applied to the precursor liquid in order to induce the formation of
such coagulates, the use of the term “cryogel” for this protein matter appears
unjustified.
Fig. 1 The number of publications (a) and citations (b) with keywords “cryogel” or “cryogels”
from 1980 to 1 November 2013 according to the ISI Web of Knowledge portal [3]
A Brief History of Polymeric Cryogels
3