246
N. N. Win and H. Morita
435. Mathankumar M, Tamizhselvi R, Manickam V, Purohit G (2015) Assessment of anticarcinogenic potential of Vitex trifolia and Triticum aestivum Linn. by in vitro rat liver microsomal
degranulation. Toxicol Int 22:114
436. Wu J, Zhou T, Zhang SW, Zhang XH, Xuan LJ (2009) Cytotoxic terpenoids from the fruits
of Vitex trifolia L. Planta Med 75:367
437. Li WX, Cui CB, Cai B, Yao XS (2005) Labdane-type diterpenes as new cell cycle inhibitors
and apoptosis inducers from Vitex trifolia L. J Asian Nat Prod Res 7:95
438. Li WX, Cui CB, Cai B, Wang HY, Yao XS (2005) Flavonoids from Vitex trifolia L. inhibit cell
cycle progression at G 2 /M phase and induce apoptosis in mammalian cancer cells. J Asian
Nat Prod Res 7:615
439. Matsui M, Adib-Conquy M, Coste A, Kumar-Roine S, Pipy B, Laurent D, Pauillac S (2012)
Aqueous extract of Vitex trifolia L. (Labiatae) inhibits LPS-dependent regulation of inflammatory mediators in RAW 264.7 macrophages through inhibition of nuclear factor kappa B
translocation and expression. J Ethnopharmacol 143:24
440. Matsui M, Kumar-Roine S, Darius HT, Chinain M, Laurent D, Pauillac S (2009) Characterisation of the anti-inflammatory potential of Vitex trifolia L. (Labiatae), a multipurpose plant
of the Pacific traditional medicine. J Ethnopharmacol 126:427
441. Kannathasan K, Senthilkumar A, Venkatesalu V (2011) Mosquito larvicidal activity of methylp-hydroxybenzoate isolated from the leaves of Vitex trifolia Linn. Acta Trop 120:115
442. Manjunatha BK, Vidya SM, Krishna V, Mankani KL, Singh SD, Manohara YN (2007)
Comparative evaluation of wound healing potency of Vitex trifolia L. and Vitex altissima
L. Phytother Res 21:457
443. Geetha V, Doss A, Doss AP (2004) Antimicrobial potential of Vitex trifolia Linn. Anc Sci
Life 23:30
444. Hossain MM, Paul N, Sohrab MH, Rahman E, Rashid MA (2001) Antibacterial activity of
Vitex trifolia. Fitoterapia 72:695
445. Hernández MM, Heraso C, Villarreal ML, Vargas-Arispuro I, Aranda E (1999) Biological
activities of crude plant extracts from Vitex trifolia L. (Verbenaceae). J Ethnopharmacol 67:37
446. Zheng CJ, Zhu JY, Yu W, Ma XQ, Rahman K, Qin LP (2013) Labdane-type diterpenoids from
the fruits of Vitex trifolia. J Nat Prod 76:287
447. Gu Q, Zhang XM, Zhou J, Qiu SX, Chen JJ (2008) One new dihydrobenzofuran lignan from
Vitex trifolia. J Asian Nat Prod Res 10:499
448. Ono M, Ito Y, Noharab T (2001) Four new halimane-type diterpenes, vitetrifolins D−G, from
the fruit of Vitex trifolia. Chem Pharm Bull 49:1220
449. Suksamrarn A, Werawattanametin K, Brophy JJ (1991) Variation of essential oil constituents
in Vitex trifolia species. Flavour Fragr J 6:97
450. Suchitra M, Cheriyan BV (2018) Vitex trifolia: An ethnobotanical and pharmacological review.
Asian J Pharm Clin Res 11:12
451. Nishina A, Itagaki M, Sato D, Kimura H, Hirai Y, Phay N, Makishima M (2017) The
rosiglitazone-like effects of vitexilactone, a constituent from Vitex trifolia L. in 3T3-L1
preadipocytes. Molecules 22:2030
452. Ono M, Yamamoto M, Yanaka T, Ito Y, Nohara T (2001) Ten new labdane-type diterpenes
from the fruit of Vitex rotundifolia. Chem Pharm Bull 49:82
453. You KM, Son KH, Chang HW, Kang SS, Kim HP (1998) Vitexicarpin, a flavonoid from the
fruits of Vitex rotundifolia, inhibits mouse lymphocyte proliferation and growth of cell lines
in vitro. Planta Med 64:546
454. Seebacher W, Simic N, Weis R, Saf R, Kunert O (2003) Complete assignments of 1 H and
13 C NMR resonances of oleanolic acid, 18α-oleanolic acid, ursolic acid and their 11-oxo
derivatives. Magn Reson Chem 41:636
455. Ukiya M, Sato D, Kimura H, Koketsu M, Phay N, Nishina A (2020) (−)-O-Methylcubebin
from Vitex trifolia enhanced adipogenesis in 3T3-L1 cells via the inhibition of ERK1/2 and
p38MAPK phosphorylation. Molecules 25:73
456. Kiralj R, Ferreira MM, Donate PM, da Silva R, Albuquerque S (2007) Conformational study of
(8α,8 β)-bis(substituted phenyl)-lignano-9,9 -lactones by means of combined computational,
database mining, NMR, and chemometric approaches. J Phys Chem A 111:6316
N. N. Win and H. Morita
435. Mathankumar M, Tamizhselvi R, Manickam V, Purohit G (2015) Assessment of anticarcinogenic potential of Vitex trifolia and Triticum aestivum Linn. by in vitro rat liver microsomal
degranulation. Toxicol Int 22:114
436. Wu J, Zhou T, Zhang SW, Zhang XH, Xuan LJ (2009) Cytotoxic terpenoids from the fruits
of Vitex trifolia L. Planta Med 75:367
437. Li WX, Cui CB, Cai B, Yao XS (2005) Labdane-type diterpenes as new cell cycle inhibitors
and apoptosis inducers from Vitex trifolia L. J Asian Nat Prod Res 7:95
438. Li WX, Cui CB, Cai B, Wang HY, Yao XS (2005) Flavonoids from Vitex trifolia L. inhibit cell
cycle progression at G 2 /M phase and induce apoptosis in mammalian cancer cells. J Asian
Nat Prod Res 7:615
439. Matsui M, Adib-Conquy M, Coste A, Kumar-Roine S, Pipy B, Laurent D, Pauillac S (2012)
Aqueous extract of Vitex trifolia L. (Labiatae) inhibits LPS-dependent regulation of inflammatory mediators in RAW 264.7 macrophages through inhibition of nuclear factor kappa B
translocation and expression. J Ethnopharmacol 143:24
440. Matsui M, Kumar-Roine S, Darius HT, Chinain M, Laurent D, Pauillac S (2009) Characterisation of the anti-inflammatory potential of Vitex trifolia L. (Labiatae), a multipurpose plant
of the Pacific traditional medicine. J Ethnopharmacol 126:427
441. Kannathasan K, Senthilkumar A, Venkatesalu V (2011) Mosquito larvicidal activity of methylp-hydroxybenzoate isolated from the leaves of Vitex trifolia Linn. Acta Trop 120:115
442. Manjunatha BK, Vidya SM, Krishna V, Mankani KL, Singh SD, Manohara YN (2007)
Comparative evaluation of wound healing potency of Vitex trifolia L. and Vitex altissima
L. Phytother Res 21:457
443. Geetha V, Doss A, Doss AP (2004) Antimicrobial potential of Vitex trifolia Linn. Anc Sci
Life 23:30
444. Hossain MM, Paul N, Sohrab MH, Rahman E, Rashid MA (2001) Antibacterial activity of
Vitex trifolia. Fitoterapia 72:695
445. Hernández MM, Heraso C, Villarreal ML, Vargas-Arispuro I, Aranda E (1999) Biological
activities of crude plant extracts from Vitex trifolia L. (Verbenaceae). J Ethnopharmacol 67:37
446. Zheng CJ, Zhu JY, Yu W, Ma XQ, Rahman K, Qin LP (2013) Labdane-type diterpenoids from
the fruits of Vitex trifolia. J Nat Prod 76:287
447. Gu Q, Zhang XM, Zhou J, Qiu SX, Chen JJ (2008) One new dihydrobenzofuran lignan from
Vitex trifolia. J Asian Nat Prod Res 10:499
448. Ono M, Ito Y, Noharab T (2001) Four new halimane-type diterpenes, vitetrifolins D−G, from
the fruit of Vitex trifolia. Chem Pharm Bull 49:1220
449. Suksamrarn A, Werawattanametin K, Brophy JJ (1991) Variation of essential oil constituents
in Vitex trifolia species. Flavour Fragr J 6:97
450. Suchitra M, Cheriyan BV (2018) Vitex trifolia: An ethnobotanical and pharmacological review.
Asian J Pharm Clin Res 11:12
451. Nishina A, Itagaki M, Sato D, Kimura H, Hirai Y, Phay N, Makishima M (2017) The
rosiglitazone-like effects of vitexilactone, a constituent from Vitex trifolia L. in 3T3-L1
preadipocytes. Molecules 22:2030
452. Ono M, Yamamoto M, Yanaka T, Ito Y, Nohara T (2001) Ten new labdane-type diterpenes
from the fruit of Vitex rotundifolia. Chem Pharm Bull 49:82
453. You KM, Son KH, Chang HW, Kang SS, Kim HP (1998) Vitexicarpin, a flavonoid from the
fruits of Vitex rotundifolia, inhibits mouse lymphocyte proliferation and growth of cell lines
in vitro. Planta Med 64:546
454. Seebacher W, Simic N, Weis R, Saf R, Kunert O (2003) Complete assignments of 1 H and
13 C NMR resonances of oleanolic acid, 18α-oleanolic acid, ursolic acid and their 11-oxo
derivatives. Magn Reson Chem 41:636
455. Ukiya M, Sato D, Kimura H, Koketsu M, Phay N, Nishina A (2020) (−)-O-Methylcubebin
from Vitex trifolia enhanced adipogenesis in 3T3-L1 cells via the inhibition of ERK1/2 and
p38MAPK phosphorylation. Molecules 25:73
456. Kiralj R, Ferreira MM, Donate PM, da Silva R, Albuquerque S (2007) Conformational study of
(8α,8 β)-bis(substituted phenyl)-lignano-9,9 -lactones by means of combined computational,
database mining, NMR, and chemometric approaches. J Phys Chem A 111:6316
