118
H. Zhu et al.
References
1. Scherlach K, Boettger D, Remme N, Hertweck C (2010) The chemistry and biology of
cytochalasans. Nat Prod Rep 27:869
2. Skellam E (2017) The biosynthesis of cytochalasans. Nat Prod Rep 34:1252
3. Long X, Ding Y, Wu H, Deng J (2019) Total synthesis of asperchalasine A. Synlett 31:301
4. Zhu H, Chen C, Tong Q, Yang J, Wei G, Xue Y, Wang J, Luo Z, Zhang Y (2017) Asperflavipine
A: a cytochalasan heterotetramer uniquely defined by a highly complex tetradecacyclic ring
system from Aspergillus flavipes QCS12. Angew Chem Int Ed 56:5242
5. Gebhardt K, Schimana J, Hoeltzel A, Dettner K, Draeger S, Beil W, Rheinheimer J, Fiedler
H-P (2004) Aspochalamins A–D and aspochalasin Z produced by the endosymbiotic fungus
Aspergillus niveus LU 9575. I. Taxonomy, fermentation, isolation and biological activities. J
Antibiot 57:707
6. Hoeltzel A, Schmid DG, Nicholson GJ, Krastel P, Zeeck A, Gebhardt K, Fielder H-P, Jung
G (2004) Aspochalamins A–D and aspochalasin Z produced by the endosymbiotic fungus
Aspergillus niveus LU 9575. II. Structure elucidation. J Antibiot 57:715
7. Li XG, Pan WD, Lou HY, Liu RM, Xiao JH, Zhong JJ (2015) New cytochalasins from
medicinal macrofungus Cordyceps taii and their inhibitory activities against human cancer
cells. Bioorg Med Chem Lett 25:1823
8. Wang C, Hantke V, Cox RJ, Skellam E (2019) Targeted gene inactivations expose silent
cytochalasans in Magnaporthe grisea NI980. Org Lett 21:4163
9. Ding G, Wang HL, Chen L, Chen AJ, Lan J, Chen XD, Zhang HW, Chen H, Liu XZ, Zou
ZM (2012) Cytochalasans with different amino-acid origin from the plant endophytic fungus
Trichoderma gamsii. J Antibiot 65:143
10. Gao W, Sun W, Li F, Chai C, Wang J, Xue Y, Chen C, Zhu H, He Y, Hu Z, Zhang Y (2018)
Armochaetoglasins A-I: cytochalasan alkaloids from fermentation broth of Chaetomium
globosum TW1-1 by feeding l-tyrosine. Phytochemistry 156:106
11. Lin ZJ, Zhang GJ, Zhu TJ, Liu R, Wei HJ, Gu QQ (2009) Bioactive cytochalasins from
Aspergillus flavipes, an endophytic fungus associated with the mangrove plant Acanthus
ilicifolius. Helv Chim Acta 92:1538
12. Zhang Y, Tian R, Liu S, Chen X, Liu X, Che Y (2008) Alachalasins A–G, new cytochalasins
from the fungus Stachybotrys chartarum. Bioorg Med Chem 16:2627
13. Aouiche A, Meklat A, Bijani C, Zitouni A, Sabaou N, Mathieu F (2015) Production of
vineomycin A1 and chaetoglobosin A by Streptomyces sp. PAL114. Ann Microbiol 65:1351
14. Chen TS, Doss GA, Hsu A, Hsu A, Lingham RB, White RF, Monaghan RL (1993) L-696,474,
a novel cytochalasin as an inhibitor of HIV-1 protease. J Nat Prod 56:755
15. Rothweiler W, Tamm C (1966) Isolation and structure of phomin. Cell Mol Life Sci 22:750
16. Aldridge DC, Armstrong JJ, Speake RN, Turner WB (1967) The cytochalasins, a new class
of biologically active mould metabolites. Chem Commun 1967:26
17. Hayakawa S, Matsushima T, Kimura T, Minato H, Katagiri K (1968) Zygosporin A, a new
antibiotic from Zygosporium masonii. J Antibiot 21:523
18. Tsukuda Y, Matsumoto M, Minato H, Koyama H (1969) Structure of zygosporin A: X-ray
analysis of isozygosporin A p-bromobenzoate. J Chem Soc D 1969:41
19. Aldridge DC, Turner WB (1969) The identity of zygosporin A and cytochalasin D. J Antibiot
22:170
20. Minato H, Matsumoto M (1970) Studies on the metabolites of Zygosporium masonii. Part I.
Structure of zygosporin A. J Chem Soc C 1970:38
21. Tsukuda Y, Koyama H (1972) Crystal structure of isozygosporin A p-bromobenzoate. J Chem
Soc Perkin Trans 2:739
22. Aldridge DC, Turner WB (1969) Structures of cytochalasins C and D. J Chem Soc 1969:923
23. Minato H, Katayama T (1970) Studies on the metabolites of Zygosporium masonii. Part II.
Structures of zygosporins D, E, F, and G. J Chem Soc C 1970:45
24. Beno MA, Christoph GG (1976) X-ray crystal structure of cytochalasin H, a potent new [11]
cytochalasan toxin. J Chem Soc Chem Commun 1976:344
H. Zhu et al.
References
1. Scherlach K, Boettger D, Remme N, Hertweck C (2010) The chemistry and biology of
cytochalasans. Nat Prod Rep 27:869
2. Skellam E (2017) The biosynthesis of cytochalasans. Nat Prod Rep 34:1252
3. Long X, Ding Y, Wu H, Deng J (2019) Total synthesis of asperchalasine A. Synlett 31:301
4. Zhu H, Chen C, Tong Q, Yang J, Wei G, Xue Y, Wang J, Luo Z, Zhang Y (2017) Asperflavipine
A: a cytochalasan heterotetramer uniquely defined by a highly complex tetradecacyclic ring
system from Aspergillus flavipes QCS12. Angew Chem Int Ed 56:5242
5. Gebhardt K, Schimana J, Hoeltzel A, Dettner K, Draeger S, Beil W, Rheinheimer J, Fiedler
H-P (2004) Aspochalamins A–D and aspochalasin Z produced by the endosymbiotic fungus
Aspergillus niveus LU 9575. I. Taxonomy, fermentation, isolation and biological activities. J
Antibiot 57:707
6. Hoeltzel A, Schmid DG, Nicholson GJ, Krastel P, Zeeck A, Gebhardt K, Fielder H-P, Jung
G (2004) Aspochalamins A–D and aspochalasin Z produced by the endosymbiotic fungus
Aspergillus niveus LU 9575. II. Structure elucidation. J Antibiot 57:715
7. Li XG, Pan WD, Lou HY, Liu RM, Xiao JH, Zhong JJ (2015) New cytochalasins from
medicinal macrofungus Cordyceps taii and their inhibitory activities against human cancer
cells. Bioorg Med Chem Lett 25:1823
8. Wang C, Hantke V, Cox RJ, Skellam E (2019) Targeted gene inactivations expose silent
cytochalasans in Magnaporthe grisea NI980. Org Lett 21:4163
9. Ding G, Wang HL, Chen L, Chen AJ, Lan J, Chen XD, Zhang HW, Chen H, Liu XZ, Zou
ZM (2012) Cytochalasans with different amino-acid origin from the plant endophytic fungus
Trichoderma gamsii. J Antibiot 65:143
10. Gao W, Sun W, Li F, Chai C, Wang J, Xue Y, Chen C, Zhu H, He Y, Hu Z, Zhang Y (2018)
Armochaetoglasins A-I: cytochalasan alkaloids from fermentation broth of Chaetomium
globosum TW1-1 by feeding l-tyrosine. Phytochemistry 156:106
11. Lin ZJ, Zhang GJ, Zhu TJ, Liu R, Wei HJ, Gu QQ (2009) Bioactive cytochalasins from
Aspergillus flavipes, an endophytic fungus associated with the mangrove plant Acanthus
ilicifolius. Helv Chim Acta 92:1538
12. Zhang Y, Tian R, Liu S, Chen X, Liu X, Che Y (2008) Alachalasins A–G, new cytochalasins
from the fungus Stachybotrys chartarum. Bioorg Med Chem 16:2627
13. Aouiche A, Meklat A, Bijani C, Zitouni A, Sabaou N, Mathieu F (2015) Production of
vineomycin A1 and chaetoglobosin A by Streptomyces sp. PAL114. Ann Microbiol 65:1351
14. Chen TS, Doss GA, Hsu A, Hsu A, Lingham RB, White RF, Monaghan RL (1993) L-696,474,
a novel cytochalasin as an inhibitor of HIV-1 protease. J Nat Prod 56:755
15. Rothweiler W, Tamm C (1966) Isolation and structure of phomin. Cell Mol Life Sci 22:750
16. Aldridge DC, Armstrong JJ, Speake RN, Turner WB (1967) The cytochalasins, a new class
of biologically active mould metabolites. Chem Commun 1967:26
17. Hayakawa S, Matsushima T, Kimura T, Minato H, Katagiri K (1968) Zygosporin A, a new
antibiotic from Zygosporium masonii. J Antibiot 21:523
18. Tsukuda Y, Matsumoto M, Minato H, Koyama H (1969) Structure of zygosporin A: X-ray
analysis of isozygosporin A p-bromobenzoate. J Chem Soc D 1969:41
19. Aldridge DC, Turner WB (1969) The identity of zygosporin A and cytochalasin D. J Antibiot
22:170
20. Minato H, Matsumoto M (1970) Studies on the metabolites of Zygosporium masonii. Part I.
Structure of zygosporin A. J Chem Soc C 1970:38
21. Tsukuda Y, Koyama H (1972) Crystal structure of isozygosporin A p-bromobenzoate. J Chem
Soc Perkin Trans 2:739
22. Aldridge DC, Turner WB (1969) Structures of cytochalasins C and D. J Chem Soc 1969:923
23. Minato H, Katayama T (1970) Studies on the metabolites of Zygosporium masonii. Part II.
Structures of zygosporins D, E, F, and G. J Chem Soc C 1970:45
24. Beno MA, Christoph GG (1976) X-ray crystal structure of cytochalasin H, a potent new [11]
cytochalasan toxin. J Chem Soc Chem Commun 1976:344
