5 Magneto-Plasmonic Nanoparticles
119
Fig. 5.4 ia Thermal images obtained with the IR camera in mice, after intratumoral injection of
nanocubes in the left-hand tumor, and after 10 min application of magnetic hyperthermia (MHT,
110 kHz, 12 mT), NIR-laser irradiation (LASER, 808 nm at 0.3 W/cm 2 ), or DUAL (both effects).
b Corresponding thermal elevation curves for all treatments and for the noninjected tumor in the
DUAL condition. c Average final temperature increase obtained after 10 min on day 0 (1 h after
injection) and 1 and 2 days after injection and for non-injected tumors. d Average tumor growth
(groups of six tumors each in non-injected mice submitted to no treatment (Control) and in nanocubeinjected mice exposed to MHT, LASER, and DUAL during the 8 days following the 3 days of treatment [183] (Reprinted from [183] with permission of the American Chemical Society). ii Comparison of the efficacy of different combinations of Photo-thermal therapy (PTT) with Photodynamic
therapy (PDT) and magnetic attraction against KB-3-1 (a) and SK-BR-3 (b) cells using Au capped
Fe oxide NPs (IOC-Au) capped with a capping layer of near-infrared absorbing photosensitizer
silicon 2,3-naphthalocyannie dihydroxide (SiNC) and/or poly(ethylene glycol) (PEG) linked with
11-mercaptoundecanoic acid (MUA) [133] (Reprinted with permission from [133]. Copyright 2017
American Chemical Society). iiia STEM-electron dispersive energy micrograph map of colistinated
FeOx/Au nanoclusters binding to A. baumannii. b Schematic of FeOx/Au nanoclusters binding to
A. baumannii bacterium (STEM micrograph) [156] (Reprinted with permission from [156]. Copyright 2017 American Chemical Society). iv In vivo T2-weighted MR images of 4T1 tumor-bearing
mice at various time points post-injection of gold nanorods @ Fe oxide core@shell particles load
with doxorubicin (GNR@IOs-DOX) without (a) or with (c) magnetic tumor targeting. White circles
indicate the positions of tumors. b, d In vivo Photoacustic images of the tumor sites at different time
points postinjection of GNR@IOs-DOX without (b) or with (d) magnetic targeting [134] (Reprinted
with permission from [134]. Copyright 2016 American Chemical Society)
119
Fig. 5.4 ia Thermal images obtained with the IR camera in mice, after intratumoral injection of
nanocubes in the left-hand tumor, and after 10 min application of magnetic hyperthermia (MHT,
110 kHz, 12 mT), NIR-laser irradiation (LASER, 808 nm at 0.3 W/cm 2 ), or DUAL (both effects).
b Corresponding thermal elevation curves for all treatments and for the noninjected tumor in the
DUAL condition. c Average final temperature increase obtained after 10 min on day 0 (1 h after
injection) and 1 and 2 days after injection and for non-injected tumors. d Average tumor growth
(groups of six tumors each in non-injected mice submitted to no treatment (Control) and in nanocubeinjected mice exposed to MHT, LASER, and DUAL during the 8 days following the 3 days of treatment [183] (Reprinted from [183] with permission of the American Chemical Society). ii Comparison of the efficacy of different combinations of Photo-thermal therapy (PTT) with Photodynamic
therapy (PDT) and magnetic attraction against KB-3-1 (a) and SK-BR-3 (b) cells using Au capped
Fe oxide NPs (IOC-Au) capped with a capping layer of near-infrared absorbing photosensitizer
silicon 2,3-naphthalocyannie dihydroxide (SiNC) and/or poly(ethylene glycol) (PEG) linked with
11-mercaptoundecanoic acid (MUA) [133] (Reprinted with permission from [133]. Copyright 2017
American Chemical Society). iiia STEM-electron dispersive energy micrograph map of colistinated
FeOx/Au nanoclusters binding to A. baumannii. b Schematic of FeOx/Au nanoclusters binding to
A. baumannii bacterium (STEM micrograph) [156] (Reprinted with permission from [156]. Copyright 2017 American Chemical Society). iv In vivo T2-weighted MR images of 4T1 tumor-bearing
mice at various time points post-injection of gold nanorods @ Fe oxide core@shell particles load
with doxorubicin (GNR@IOs-DOX) without (a) or with (c) magnetic tumor targeting. White circles
indicate the positions of tumors. b, d In vivo Photoacustic images of the tumor sites at different time
points postinjection of GNR@IOs-DOX without (b) or with (d) magnetic targeting [134] (Reprinted
with permission from [134]. Copyright 2016 American Chemical Society)