68.08 MPa and elongation to break (EB) of 36.62% in developed films at pH 12 and
90
C. Film which was formulated at pH 10 and 60
C exhibited prominent free
radical scavenging activity using ABTS test. In another study, Popović et al. (2012)
developed biodegradable films using pumpkin oil cake protein isolate (PuOC PI) at
various pH (2–12) levels and plasticizer concentration, i.e., 0.3–0.6 g glycerol/g of
PuOC PI. The study revealed the possibility of PuOC PI film formation over a broad
range of pH with the only exception at pH 4–8. Gas permeability analysis of films
formulated at 0.4 g glycerol/g PuOC PI concentration demonstrated superior barrier
activity for gases like oxygen, nitrogen, carbon-di-oxide, and air. The authors
concluded that due to enhanced break elongation and superior gas barrier activity
pumpkin oil cake can be used to develop stretchable coating having gas barrier
activity.
19.11.2 In Pharmaceutical Industry
In a randomized, placebo-controlled, double-blind study positive effect on hair
growth was observed after supplementation of pumpkin seed oil for 24 weeks in
male patients having androgenetic alopecia of mild to moderate level (Cho et al.
2014). Cold press pumpkin seed oil found to have tocopherols, sterols, and polyunsaturated fatty acids which also demonstrated strong antioxidant and antimicrobial
activity. It may offer valuable protection against skin diseases like dermatological
wounds. These properties of pumpkin seed oil can be exploited in pharmaceutical
and cosmetic industry (Bardaa et al. 2016).
Hataminia and Farhadian (2017) have offered safe and controllable process for
adsorption of fatty acids (FA) of pumpkin seed on iron oxide nanoparticles to
facilitate its application in pharmacotherapy. The study showed that particles had
superparamagnetic property and net charge of 52 mv, making it appropriate for its
application in the pharmaceutical industry. Under optimum conditions TEM analysis
with spherical morphology demonstrated about 20 nm estimated particle size. The
predictable thickness of fatty acids on nanoparticles surface was around 5 nm. Fatty
acid layers were formed around nanoparticles which was obvious in Fourier transform infrared spectroscopy (FTIR). Oil can be used in the treatments of prostate and
skin cancer. The loading of substrate having therapeutic potential provides newer
drug delivery mechanism.
19.11.3 In Cattle-Feed Industry
Klir et al. (2017) evaluated the quality of goat milk by replacing the soybean meal in
goat’s diet with that of pumpkin seed cake (PSC) or extruded linseed (ELS). The
pumpkin seed cake (PSC) diet reduced total ω-6 fatty acids (2.96 vs. 3.54 g/100 g
498
S. Adsul and V. Madkaikar
90
C. Film which was formulated at pH 10 and 60
C exhibited prominent free
radical scavenging activity using ABTS test. In another study, Popović et al. (2012)
developed biodegradable films using pumpkin oil cake protein isolate (PuOC PI) at
various pH (2–12) levels and plasticizer concentration, i.e., 0.3–0.6 g glycerol/g of
PuOC PI. The study revealed the possibility of PuOC PI film formation over a broad
range of pH with the only exception at pH 4–8. Gas permeability analysis of films
formulated at 0.4 g glycerol/g PuOC PI concentration demonstrated superior barrier
activity for gases like oxygen, nitrogen, carbon-di-oxide, and air. The authors
concluded that due to enhanced break elongation and superior gas barrier activity
pumpkin oil cake can be used to develop stretchable coating having gas barrier
activity.
19.11.2 In Pharmaceutical Industry
In a randomized, placebo-controlled, double-blind study positive effect on hair
growth was observed after supplementation of pumpkin seed oil for 24 weeks in
male patients having androgenetic alopecia of mild to moderate level (Cho et al.
2014). Cold press pumpkin seed oil found to have tocopherols, sterols, and polyunsaturated fatty acids which also demonstrated strong antioxidant and antimicrobial
activity. It may offer valuable protection against skin diseases like dermatological
wounds. These properties of pumpkin seed oil can be exploited in pharmaceutical
and cosmetic industry (Bardaa et al. 2016).
Hataminia and Farhadian (2017) have offered safe and controllable process for
adsorption of fatty acids (FA) of pumpkin seed on iron oxide nanoparticles to
facilitate its application in pharmacotherapy. The study showed that particles had
superparamagnetic property and net charge of 52 mv, making it appropriate for its
application in the pharmaceutical industry. Under optimum conditions TEM analysis
with spherical morphology demonstrated about 20 nm estimated particle size. The
predictable thickness of fatty acids on nanoparticles surface was around 5 nm. Fatty
acid layers were formed around nanoparticles which was obvious in Fourier transform infrared spectroscopy (FTIR). Oil can be used in the treatments of prostate and
skin cancer. The loading of substrate having therapeutic potential provides newer
drug delivery mechanism.
19.11.3 In Cattle-Feed Industry
Klir et al. (2017) evaluated the quality of goat milk by replacing the soybean meal in
goat’s diet with that of pumpkin seed cake (PSC) or extruded linseed (ELS). The
pumpkin seed cake (PSC) diet reduced total ω-6 fatty acids (2.96 vs. 3.54 g/100 g
498
S. Adsul and V. Madkaikar