In context to the above report, Mohamad et al. (2017) studied the anti-obesity and
anti-inflammatory effects of coconut water vinegar on high-fat-diet (HFD)-induced
obese mice. C57/BL mice were fed with an HFD diet continuously for 33 weeks to
persuade obesity. Obese mice were fed with coconut water vinegar at a rate of 0.08
and 2 mL/kg body weight from week 24 to 33. The oral ingestion reduced the body
weight, serum lipid profile, and fat-pad weight of obese mice significantly
( p < 0.05). This would be achieved by alterations in the gut microbiota through
an increase in the populations of the Bacteroides and Akkermansia genera by the
coconut water vinegar that may have helped to overcome the obesity and inflammation caused by the HFD.
With a fact that consumption of MCTGs in overweight adults reduces obesity
through increased thermogenesis, LaBarrie and St-Onge (2017) conducted a doubleblind, cross-over study on 15 children of 13–18 years of age by feeding them two test
meals containing 20 g fat which was corn oil or coconut oil-enriched baking fat.
They observed a significant effect of fat type on leptin (P ¼ 0.027), peptide YY
(P ¼ 0.0085), and triglycerides (P ¼ 0.020). The concentration of leptin and
triglyceride was lowered, while peptide YY concentrations were increased in comparison with corn oil consumption.
From the two studies cited above, it can be concluded that coconut oil and
coconut water can be used as a body weight management tool, but some more
research is needed to demonstrate it.
7.5.16 Renal Protective Effect
Urolithiasis is a common occurrence affecting up to 10%–15% of the globe at some
point during their lifetime (Long and Park 2007). Due to improved living standards,
race, ethnicity, and geographical location increased the incidence of kidney stones in
the world (Stamatelou et al. 2003). Many medicinal plants have been used to treat
urinary stones since ancient times. Coconut water serves the same. To evaluate its
renal protective ability, Gandhi et al. (2013) studied the prophylactic effect of
coconut water against nephrolithiasis-induced kidney stones in Wistar rats. They
were divided into three groups: control (standard diet), induced nephrolithiasis rats
fed with 0.75% ethylene glycol in drinking water, and in third group coconut water
instead of ethylene glycol for 7 weeks. The urine sample analysis showed a tremendous reduction in calcium oxalate crystals in coconut water-fed rats. It significantly
( p < 0.05) reduced urea and creatinine levels in group 3. Based on the results of the
study, it can be suggested that coconut water has renal protective activity, and
coconut water can be investigated for its potential in the treatment of kidney stones
in humans.
180
P. T. Parmar et al.
anti-inflammatory effects of coconut water vinegar on high-fat-diet (HFD)-induced
obese mice. C57/BL mice were fed with an HFD diet continuously for 33 weeks to
persuade obesity. Obese mice were fed with coconut water vinegar at a rate of 0.08
and 2 mL/kg body weight from week 24 to 33. The oral ingestion reduced the body
weight, serum lipid profile, and fat-pad weight of obese mice significantly
( p < 0.05). This would be achieved by alterations in the gut microbiota through
an increase in the populations of the Bacteroides and Akkermansia genera by the
coconut water vinegar that may have helped to overcome the obesity and inflammation caused by the HFD.
With a fact that consumption of MCTGs in overweight adults reduces obesity
through increased thermogenesis, LaBarrie and St-Onge (2017) conducted a doubleblind, cross-over study on 15 children of 13–18 years of age by feeding them two test
meals containing 20 g fat which was corn oil or coconut oil-enriched baking fat.
They observed a significant effect of fat type on leptin (P ¼ 0.027), peptide YY
(P ¼ 0.0085), and triglycerides (P ¼ 0.020). The concentration of leptin and
triglyceride was lowered, while peptide YY concentrations were increased in comparison with corn oil consumption.
From the two studies cited above, it can be concluded that coconut oil and
coconut water can be used as a body weight management tool, but some more
research is needed to demonstrate it.
7.5.16 Renal Protective Effect
Urolithiasis is a common occurrence affecting up to 10%–15% of the globe at some
point during their lifetime (Long and Park 2007). Due to improved living standards,
race, ethnicity, and geographical location increased the incidence of kidney stones in
the world (Stamatelou et al. 2003). Many medicinal plants have been used to treat
urinary stones since ancient times. Coconut water serves the same. To evaluate its
renal protective ability, Gandhi et al. (2013) studied the prophylactic effect of
coconut water against nephrolithiasis-induced kidney stones in Wistar rats. They
were divided into three groups: control (standard diet), induced nephrolithiasis rats
fed with 0.75% ethylene glycol in drinking water, and in third group coconut water
instead of ethylene glycol for 7 weeks. The urine sample analysis showed a tremendous reduction in calcium oxalate crystals in coconut water-fed rats. It significantly
( p < 0.05) reduced urea and creatinine levels in group 3. Based on the results of the
study, it can be suggested that coconut water has renal protective activity, and
coconut water can be investigated for its potential in the treatment of kidney stones
in humans.
180
P. T. Parmar et al.