218
A. Fainsod et al.
Grandel H, Lun K, Rauch G-J, Rhinn M, Piotrowski T, Houart C, Sordino P et al (2002) Retinoic
acid signalling in the zebrafish embryo is necessary during pre-segmentation stages to pattern the
anterior-posterior axis of the CNS and to induce a pectoral fin bud. Development (Cambridge,
England) 129:2851–2865
Green RF, Stoler JM (2007) Alcohol dehydrogenase 1B genotype and fetal alcohol syndrome: a
HuGE minireview. Am J Obstet Gynecol 197:12–25
Grummer MA, Zachman RD (1990) The effect of maternal ethanol ingestion on fetal vitamin A in
the rat. Pediatr Res 28:186–189
Guerri C, Bazinet A, Riley EP (2009) Foetal Alcohol Spectrum Disorders and alterations in brain
and behaviour. Alcohol Alcohol 44:108–114
Guerri C, Sanchis R (1985) Acetaldehyde and alcohol levels in pregnant rats and their fetuses.
Alcohol (Fayetteville, NY) 2:267–270
Gupta KK, Gupta VK, Shirasaka T (2016) An Update on Fetal Alcohol Syndrome-Pathogenesis,
Risks, and Treatment. Alcohol Clin Exp Res 40:1594–1602
Hale F (1935) The relation of vitamin a to anophthalmos in pigs. Am J Ophthalmol 18:1087–1093
Halilagic A, Ribes V, Ghyselinck NB, Zile MH, Dollé P, Studer M (2007) Retinoids control anterior
and dorsal properties in the developing forebrain. Dev Biol 303:362–375
Halvorson MR, Noffsinger JK, Peterson CM (1993) Studies of whole blood-associated acetaldehyde
levels in teetotalers. Alcohol (Fayetteville, NY) 10:409–413
Harcombe AA, Ramsay L, Kenna JG, Koskinas J, Why HJ, Richardson PJ, Weissberg PL et al
(1995) Circulating antibodies to cardiac protein-acetaldehyde adducts in alcoholic heart muscle
disease. Clin Sci (London, England: 1979) 88:263–268
Harrison EH, Quadro L (2018) Apocarotenoids: emerging roles in mammals. Annu Rev Nutr
38:153–172
Harris SR, Osborn JA, Weinberg J, Loock C, Junaid K (1993) Effects of prenatal alcohol exposure
on neuromotor and cognitive development during early childhood: a series of case reports. Phys
Therapy 73:608–617
Heller M, Burd L (2014) Review of ethanol dispersion, distribution, and elimination from the fetal
compartment. Birth Defects Res Part A Clin Mol Teratol 100:277–283
Herrmann J, Pallister PD, Opitz JM (1980) Tetraectrodactyly and other skeletal manifestations in
the fetal alcohol syndrome. Eur J Pediatr 133:221–226
Hertwig O (1892) Urmund und Spina bifida. Archiv für Mikroskopische Anatomie 39:353–502
Hoffmann T, Meyer RJ, Sorrell MF, Tuma DJ (1993) Reaction of acetaldehyde with proteins:
formation of stable fluorescent adducts. Alcohol Clin Exp Res 17:69–74
Hollemann T, Chen Y, Grunz H, Pieler T (1998) Regionalized metabolic activity establishes
boundaries of retinoic acid signalling. EMBO J 17:7361–7372
Hou N, Ren L, Gong M, Bi Y, Gu Y, Dong Z, Liu Y et al (2015) Vitamin A deficiency impairs
spatial learning and memory: the mechanism of abnormal CBP-dependent histone acetylation
regulated by retinoic acid receptor alpha. Mol Neurobiol 51:633–647
Hoyme, H. E., W. O. Kalberg, A. J. Elliott, J. Blankenship, D. Buckley, A.-S. Marais, M. A. Manning,
et al. 2016. Updated clinical guidelines for diagnosing fetal alcohol spectrum disorders. Pediatrics
138
Hurley TD, Edenberg HJ (2012) Genes encoding enzymes involved in ethanol metabolism. Alcohol
Res Curr Rev 34:339–344
Jacobson SW, Carr LG, Croxford J, Sokol RJ, Li T-K, Jacobson JL (2006) Protective effects of the
alcohol dehydrogenase-ADH1B allele in children exposed to alcohol during pregnancy. J Pediatr
148:30–37
Janesick A, Shiotsugu J, Taketani M, Blumberg B (2012) RIPPLY3 is a retinoic acid-inducible
repressor required for setting the borders of the pre-placodal ectoderm. Development 139:1213–
1224
Janesick, A, Nguyen TTL, Aisaki K, Igarashi K, Kitajima S, Chandraratna RAS, Kanno J,
et al (2014) Active repression by RARγ signaling is required for vertebrate axial elongation.
Development 141:2260–2270
A. Fainsod et al.
Grandel H, Lun K, Rauch G-J, Rhinn M, Piotrowski T, Houart C, Sordino P et al (2002) Retinoic
acid signalling in the zebrafish embryo is necessary during pre-segmentation stages to pattern the
anterior-posterior axis of the CNS and to induce a pectoral fin bud. Development (Cambridge,
England) 129:2851–2865
Green RF, Stoler JM (2007) Alcohol dehydrogenase 1B genotype and fetal alcohol syndrome: a
HuGE minireview. Am J Obstet Gynecol 197:12–25
Grummer MA, Zachman RD (1990) The effect of maternal ethanol ingestion on fetal vitamin A in
the rat. Pediatr Res 28:186–189
Guerri C, Bazinet A, Riley EP (2009) Foetal Alcohol Spectrum Disorders and alterations in brain
and behaviour. Alcohol Alcohol 44:108–114
Guerri C, Sanchis R (1985) Acetaldehyde and alcohol levels in pregnant rats and their fetuses.
Alcohol (Fayetteville, NY) 2:267–270
Gupta KK, Gupta VK, Shirasaka T (2016) An Update on Fetal Alcohol Syndrome-Pathogenesis,
Risks, and Treatment. Alcohol Clin Exp Res 40:1594–1602
Hale F (1935) The relation of vitamin a to anophthalmos in pigs. Am J Ophthalmol 18:1087–1093
Halilagic A, Ribes V, Ghyselinck NB, Zile MH, Dollé P, Studer M (2007) Retinoids control anterior
and dorsal properties in the developing forebrain. Dev Biol 303:362–375
Halvorson MR, Noffsinger JK, Peterson CM (1993) Studies of whole blood-associated acetaldehyde
levels in teetotalers. Alcohol (Fayetteville, NY) 10:409–413
Harcombe AA, Ramsay L, Kenna JG, Koskinas J, Why HJ, Richardson PJ, Weissberg PL et al
(1995) Circulating antibodies to cardiac protein-acetaldehyde adducts in alcoholic heart muscle
disease. Clin Sci (London, England: 1979) 88:263–268
Harrison EH, Quadro L (2018) Apocarotenoids: emerging roles in mammals. Annu Rev Nutr
38:153–172
Harris SR, Osborn JA, Weinberg J, Loock C, Junaid K (1993) Effects of prenatal alcohol exposure
on neuromotor and cognitive development during early childhood: a series of case reports. Phys
Therapy 73:608–617
Heller M, Burd L (2014) Review of ethanol dispersion, distribution, and elimination from the fetal
compartment. Birth Defects Res Part A Clin Mol Teratol 100:277–283
Herrmann J, Pallister PD, Opitz JM (1980) Tetraectrodactyly and other skeletal manifestations in
the fetal alcohol syndrome. Eur J Pediatr 133:221–226
Hertwig O (1892) Urmund und Spina bifida. Archiv für Mikroskopische Anatomie 39:353–502
Hoffmann T, Meyer RJ, Sorrell MF, Tuma DJ (1993) Reaction of acetaldehyde with proteins:
formation of stable fluorescent adducts. Alcohol Clin Exp Res 17:69–74
Hollemann T, Chen Y, Grunz H, Pieler T (1998) Regionalized metabolic activity establishes
boundaries of retinoic acid signalling. EMBO J 17:7361–7372
Hou N, Ren L, Gong M, Bi Y, Gu Y, Dong Z, Liu Y et al (2015) Vitamin A deficiency impairs
spatial learning and memory: the mechanism of abnormal CBP-dependent histone acetylation
regulated by retinoic acid receptor alpha. Mol Neurobiol 51:633–647
Hoyme, H. E., W. O. Kalberg, A. J. Elliott, J. Blankenship, D. Buckley, A.-S. Marais, M. A. Manning,
et al. 2016. Updated clinical guidelines for diagnosing fetal alcohol spectrum disorders. Pediatrics
138
Hurley TD, Edenberg HJ (2012) Genes encoding enzymes involved in ethanol metabolism. Alcohol
Res Curr Rev 34:339–344
Jacobson SW, Carr LG, Croxford J, Sokol RJ, Li T-K, Jacobson JL (2006) Protective effects of the
alcohol dehydrogenase-ADH1B allele in children exposed to alcohol during pregnancy. J Pediatr
148:30–37
Janesick A, Shiotsugu J, Taketani M, Blumberg B (2012) RIPPLY3 is a retinoic acid-inducible
repressor required for setting the borders of the pre-placodal ectoderm. Development 139:1213–
1224
Janesick, A, Nguyen TTL, Aisaki K, Igarashi K, Kitajima S, Chandraratna RAS, Kanno J,
et al (2014) Active repression by RARγ signaling is required for vertebrate axial elongation.
Development 141:2260–2270