140
E. Perl and J. S. Waxman
vitamin A homeostasis in tissues other than the eye. J Biol Chem 288:24528–39. https://doi.org/
10.1074/jbc.M113.484014
Bertrand N, Roux M, Ryckebüsch L, Niederreither K, Dollé P, Moon A, Capecchi M, Zaffran S
(2011) Hox genes define distinct progenitor sub-domains within the second heart field. Dev Biol
353:266–274. https://doi.org/10.1016/j.ydbio.2011.02.029
Bertrand S, Thisse B, Tavares R, Sachs L, Chaumot A, Bardet P-L, Escrivà H, Duffraisse M,
Marchand O, Safi R, Thisse C, Laudet V (2007) Unexpected Novel Relational Links Uncovered
by Extensive Developmental Profiling of Nuclear Receptor Expression. PLoS Genet 3:e188.
https://doi.org/10.1371/journal.pgen.0030188
Betts GJ, Desiax P, Johnson E, Johnson JE, Korol O, Kruse D, Pore B, Wise JA, Womble M, Young
KA. Anatomy & Physiology. OpenStax, Texas
Billings SE, Pierzchalski K, Butler Tjaden NE, Pang X-Y, Trainor PA, Kane MA, Moise AR (2013)
The retinaldehyde reductase DHRS3 is essential for preventing the formation of excess retinoic
acid during embryonic development. FASEB J. 27:4877–89. https://doi.org/10.1096/fj.13-227967
Brade T, Kumar S, Cunningham TJ, Chatzi C, Zhao X, Cavallero S, Li P, Sucov HM, Ruiz-Lozano
P, Duester G (2011) Retinoic acid stimulates myocardial expansion by induction of hepatic
erythropoietin which activates epicardial Igf2. Development. 138:139–148. https://doi.org/10.
1242/dev.054239
Braitsch CM, Combs MD, Quaggin SE, Yutzey KE (2012) Pod1/Tcf21 is regulated by retinoic
acid signaling and inhibits differentiation of epicardium-derived cells into smooth muscle in the
developing heart. Dev Biol 368:345–357. https://doi.org/10.1016/j.ydbio.2012.06.002
Buckingham M. First and Second Heart Field. In: Congenital Heart Diseases: The Broken Heart.
Springer Vienna, Vienna, pp 25–40
Buenrostro JD, Giresi PG, Zaba LC, Chang HY, Greenleaf WJ (2013) Transposition of native
chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins
and nucleosome position. Nat Methods 10:1213–8. https://doi.org/10.1038/nmeth.2688
Cavanaugh AM, Huang J, Chen J-N (2015) Two developmentally distinct populations of neural
crest cells contribute to the zebrafish heart. Dev Biol 404:103–112. https://doi.org/10.1016/j.
ydbio.2015.06.002
Chatzi C, Cunningham TJ, Duester G (2013) Investigation of retinoic acid function during
embryonic brain development using retinaldehyde-rescued Rdh10 knockout mice. Dev Dyn
242:1056–1065. https://doi.org/10.1002/dvdy.23999
Chen J, Kubalak SW, Chien KR (1998) Ventricular muscle-restricted targeting of the RXRalpha gene
reveals a non-cell-autonomous requirement in cardiac chamber morphogenesis. Development.
125:1943–9
Cohlan SQ. Excessive intake of vitamin A as a cause of congenital anomalies in the rat. Science
(80-). 1953; 117:535–536. https://doi.org/10.1126/science.117.3046.535
Collop AH, Broomfield JAS, Chandraratna RAS, Yong Z, Deimling SJ, Kolker SJ, Weeks DL,
Drysdale TA (2006) Retinoic acid signaling is essential for formation of the heart tube in Xenopus.
Dev Biol 291:96–109. https://doi.org/10.1016/j.ydbio.2005.12.018
Cubuk PO, Ho L, Reversade B, Perçin EF (2016) MATTHEW-WOOD SYNDROME: A CASE
WITH DEXTROCARDIA AND STREAK GONADS. Genet Couns 27:405–410
Cunningham TJ, Zhao X, Sandell LL, Evans SM, Trainor PA, Duester G (2013) Antagonism
between Retinoic Acid and Fibroblast Growth Factor Signaling during Limb Development. Cell
Rep. 3:1503–1511. https://doi.org/10.1016/j.celrep.2013.03.036
D’Aniello E, Ravisankar P, Waxman JS (2015) Rdh10a Provides a Conserved Critical Step in the
Synthesis of Retinoic Acid during Zebrafish Embryogenesis. PLoS ONE 10:e0138588. https://
doi.org/10.1371/journal.pone.0138588
D’Aniello E, Rydeen AB, Anderson JL, Mandal A, Waxman JS (2013) Depletion of Retinoic Acid
Receptors Initiates a Novel Positive Feedback Mechanism that Promotes Teratogenic Increases
in Retinoic Acid. PLoS Genet 9:e1003689. https://doi.org/10.1371/journal.pgen.1003689
E. Perl and J. S. Waxman
vitamin A homeostasis in tissues other than the eye. J Biol Chem 288:24528–39. https://doi.org/
10.1074/jbc.M113.484014
Bertrand N, Roux M, Ryckebüsch L, Niederreither K, Dollé P, Moon A, Capecchi M, Zaffran S
(2011) Hox genes define distinct progenitor sub-domains within the second heart field. Dev Biol
353:266–274. https://doi.org/10.1016/j.ydbio.2011.02.029
Bertrand S, Thisse B, Tavares R, Sachs L, Chaumot A, Bardet P-L, Escrivà H, Duffraisse M,
Marchand O, Safi R, Thisse C, Laudet V (2007) Unexpected Novel Relational Links Uncovered
by Extensive Developmental Profiling of Nuclear Receptor Expression. PLoS Genet 3:e188.
https://doi.org/10.1371/journal.pgen.0030188
Betts GJ, Desiax P, Johnson E, Johnson JE, Korol O, Kruse D, Pore B, Wise JA, Womble M, Young
KA. Anatomy & Physiology. OpenStax, Texas
Billings SE, Pierzchalski K, Butler Tjaden NE, Pang X-Y, Trainor PA, Kane MA, Moise AR (2013)
The retinaldehyde reductase DHRS3 is essential for preventing the formation of excess retinoic
acid during embryonic development. FASEB J. 27:4877–89. https://doi.org/10.1096/fj.13-227967
Brade T, Kumar S, Cunningham TJ, Chatzi C, Zhao X, Cavallero S, Li P, Sucov HM, Ruiz-Lozano
P, Duester G (2011) Retinoic acid stimulates myocardial expansion by induction of hepatic
erythropoietin which activates epicardial Igf2. Development. 138:139–148. https://doi.org/10.
1242/dev.054239
Braitsch CM, Combs MD, Quaggin SE, Yutzey KE (2012) Pod1/Tcf21 is regulated by retinoic
acid signaling and inhibits differentiation of epicardium-derived cells into smooth muscle in the
developing heart. Dev Biol 368:345–357. https://doi.org/10.1016/j.ydbio.2012.06.002
Buckingham M. First and Second Heart Field. In: Congenital Heart Diseases: The Broken Heart.
Springer Vienna, Vienna, pp 25–40
Buenrostro JD, Giresi PG, Zaba LC, Chang HY, Greenleaf WJ (2013) Transposition of native
chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins
and nucleosome position. Nat Methods 10:1213–8. https://doi.org/10.1038/nmeth.2688
Cavanaugh AM, Huang J, Chen J-N (2015) Two developmentally distinct populations of neural
crest cells contribute to the zebrafish heart. Dev Biol 404:103–112. https://doi.org/10.1016/j.
ydbio.2015.06.002
Chatzi C, Cunningham TJ, Duester G (2013) Investigation of retinoic acid function during
embryonic brain development using retinaldehyde-rescued Rdh10 knockout mice. Dev Dyn
242:1056–1065. https://doi.org/10.1002/dvdy.23999
Chen J, Kubalak SW, Chien KR (1998) Ventricular muscle-restricted targeting of the RXRalpha gene
reveals a non-cell-autonomous requirement in cardiac chamber morphogenesis. Development.
125:1943–9
Cohlan SQ. Excessive intake of vitamin A as a cause of congenital anomalies in the rat. Science
(80-). 1953; 117:535–536. https://doi.org/10.1126/science.117.3046.535
Collop AH, Broomfield JAS, Chandraratna RAS, Yong Z, Deimling SJ, Kolker SJ, Weeks DL,
Drysdale TA (2006) Retinoic acid signaling is essential for formation of the heart tube in Xenopus.
Dev Biol 291:96–109. https://doi.org/10.1016/j.ydbio.2005.12.018
Cubuk PO, Ho L, Reversade B, Perçin EF (2016) MATTHEW-WOOD SYNDROME: A CASE
WITH DEXTROCARDIA AND STREAK GONADS. Genet Couns 27:405–410
Cunningham TJ, Zhao X, Sandell LL, Evans SM, Trainor PA, Duester G (2013) Antagonism
between Retinoic Acid and Fibroblast Growth Factor Signaling during Limb Development. Cell
Rep. 3:1503–1511. https://doi.org/10.1016/j.celrep.2013.03.036
D’Aniello E, Ravisankar P, Waxman JS (2015) Rdh10a Provides a Conserved Critical Step in the
Synthesis of Retinoic Acid during Zebrafish Embryogenesis. PLoS ONE 10:e0138588. https://
doi.org/10.1371/journal.pone.0138588
D’Aniello E, Rydeen AB, Anderson JL, Mandal A, Waxman JS (2013) Depletion of Retinoic Acid
Receptors Initiates a Novel Positive Feedback Mechanism that Promotes Teratogenic Increases
in Retinoic Acid. PLoS Genet 9:e1003689. https://doi.org/10.1371/journal.pgen.1003689