Contents
Preface . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
v
Contributors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
ix
PART I DESIGN PRINCIPLES
1 Biomimetic Boundary-Based Scaffold Design for Tissue
Engineering Applications . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
3
Henrique A. Almeida and Paulo J. Ba ´ rtolo
2 Triply Periodic Minimal Surfaces (TPMS) for the Generation
of Porous Architectures Using Stereolithography . . . . . . . . . . . . . . . . . . . . . . . . . . . 19
Sebastien B. G. Blanquer and Dirk W. Grijpma
3 3D Printing of Functionally Graded Films by Controlling
Process Parameters . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 31
Alessandra Bonfanti, Loris Domenicale, and Atul Bhaskar
PART II BIOMATERIALS FOR COMPUTER-AIDED TISSUE ENGINEERING
4 Photocurable Biopolymers for Coaxial Bioprinting . . . . . . . . . . . . . . . . . . . . . . . . . . 45
Marco Costantini, Andrea Barbetta, Wojciech Swieszkowski,
Dror Seliktar, Cesare Gargioli, and Alberto Rainer
5 Synthesis of an UV-Curable Divinyl-Fumarate Poly-ε-Caprolactone
for Stereolithography Applications . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 55
Alfredo Ronca, Sara Ronca, Giuseppe Forte, and Luigi Ambrosio
6 Nanocomposite Clay-Based Bioinks for Skeletal Tissue Engineering. . . . . . . . . . . 63
Gianluca Cidonio, Michael Glinka, Yang-Hee Kim,
Jonathan I. Dawson, and Richard O. C. Oreffo
PART III TECHNOLOGICAL PLATFORMS AND MANUFACTURING PROCESSES
7 Additive Manufacturing Using Melt Extruded Thermoplastics
for Tissue Engineering. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 75
Andrea Roberto Calore, Ravi Sinha, Jules Harings,
Katrien V. Bernaerts, Carlos Mota, and Lorenzo Moroni
8 Computer-Aided Wet-Spinning . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 101
Dario Puppi and Federica Chiellini
9 Production of Scaffolds Using Melt Electrospinning Writing
and Cell Seeding . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 111
Eleonore C. L. Bolle, Deanna Nicdao, Paul D. Dalton,
and Tim R. Dargaville
10 Low-Voltage Continuous Electrospinning: A Versatile Protocol
for Patterning Nano- and Micro-Scaled Fibers for Cell Interface. . . . . . . . . . . . . . 125
Zhaoying Li, Xia Li, and Yan Yan Shery Huang
vii
Preface . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
v
Contributors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
ix
PART I DESIGN PRINCIPLES
1 Biomimetic Boundary-Based Scaffold Design for Tissue
Engineering Applications . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
3
Henrique A. Almeida and Paulo J. Ba ´ rtolo
2 Triply Periodic Minimal Surfaces (TPMS) for the Generation
of Porous Architectures Using Stereolithography . . . . . . . . . . . . . . . . . . . . . . . . . . . 19
Sebastien B. G. Blanquer and Dirk W. Grijpma
3 3D Printing of Functionally Graded Films by Controlling
Process Parameters . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 31
Alessandra Bonfanti, Loris Domenicale, and Atul Bhaskar
PART II BIOMATERIALS FOR COMPUTER-AIDED TISSUE ENGINEERING
4 Photocurable Biopolymers for Coaxial Bioprinting . . . . . . . . . . . . . . . . . . . . . . . . . . 45
Marco Costantini, Andrea Barbetta, Wojciech Swieszkowski,
Dror Seliktar, Cesare Gargioli, and Alberto Rainer
5 Synthesis of an UV-Curable Divinyl-Fumarate Poly-ε-Caprolactone
for Stereolithography Applications . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 55
Alfredo Ronca, Sara Ronca, Giuseppe Forte, and Luigi Ambrosio
6 Nanocomposite Clay-Based Bioinks for Skeletal Tissue Engineering. . . . . . . . . . . 63
Gianluca Cidonio, Michael Glinka, Yang-Hee Kim,
Jonathan I. Dawson, and Richard O. C. Oreffo
PART III TECHNOLOGICAL PLATFORMS AND MANUFACTURING PROCESSES
7 Additive Manufacturing Using Melt Extruded Thermoplastics
for Tissue Engineering. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 75
Andrea Roberto Calore, Ravi Sinha, Jules Harings,
Katrien V. Bernaerts, Carlos Mota, and Lorenzo Moroni
8 Computer-Aided Wet-Spinning . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 101
Dario Puppi and Federica Chiellini
9 Production of Scaffolds Using Melt Electrospinning Writing
and Cell Seeding . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 111
Eleonore C. L. Bolle, Deanna Nicdao, Paul D. Dalton,
and Tim R. Dargaville
10 Low-Voltage Continuous Electrospinning: A Versatile Protocol
for Patterning Nano- and Micro-Scaled Fibers for Cell Interface. . . . . . . . . . . . . . 125
Zhaoying Li, Xia Li, and Yan Yan Shery Huang
vii