56
2 Synthesis of In-Tether Chiral Center Peptides …
NH-CH region of 2D-NOESY spectrum of 1b
(at 500 MHz in H 2 O with 10% D 2 O at 298 K) asterisk indicates peak overlap)
N
H
H
N
N
H
H
N
H
N
NH 2
O
O
O
O
O
Ala
Ala
Ala
O
S
Ph
peptide 2b
TOCSY spectrum of 2b (500 MHz in H 2 O with 10% D 2 O at 298 K)
2 Synthesis of In-Tether Chiral Center Peptides …
NH-CH region of 2D-NOESY spectrum of 1b
(at 500 MHz in H 2 O with 10% D 2 O at 298 K) asterisk indicates peak overlap)
N
H
H
N
N
H
H
N
H
N
NH 2
O
O
O
O
O
Ala
Ala
Ala
O
S
Ph
peptide 2b
TOCSY spectrum of 2b (500 MHz in H 2 O with 10% D 2 O at 298 K)