64. Arai T, Moribatake T, Masu H (2015) Chiral bis(imidazolidine)-derived NCN pincer Rh
complex for catalytic asymmetric mannich reaction of malononitrile with N-Boc imines.
Chem Eur J 21:10671–10675
65. Hyodo K, Nakamura S, Tsuji K, Ogawa T, Funahashi Y, Shibata N (2011) Enantioselective
reaction of imines and benzyl nitriles using palladium pincer complexes with C2-symmetric
chiral bis(imidazoline)s. Adv Synth Catal 353:3385–3390
66. Hyodo K, Kondo M, Funahashi Y, Nakamura S (2013) Catalytic enantioselective
decarboxylative cyanoalkylation of imines by using palladium pincer complexes with
C2-symmetric chiral bis(imidazoline)s. Chem Eur J 19:4128–4134
67. Kondo M, Kobayashi N, Hatanaka T, Funahashi Y, Nakamura S (2015) Catalytic
enantioselective reaction of alpha-phenylthioacetonitriles with imines using chiral bis
(imidazoline)-palladium catalysts. Chem Eur J 21:9066–9070
68. Kondo M, Nishi T, Hatanaka T, Funahashi Y, Nakamura S (2015) Catalytic enantioselective
reaction of alpha-aminoacetonitriles using chiral bis(imidazoline) palladium catalysts. Angew
Chem Int Ed 54:8198–8202
69. Kondo M, Sugimoto M, Nakamura S (2016) Direct catalytic enantioselective Mannich-type
reaction of dichloroacetonitrile using bis(imidazoline)-Pd catalysts. Chem Commun
52:13604–13607
70. Kondo M, Omori M, Hatanaka T, Funahashi Y, Nakamura S (2017) Catalytic enantioselective
reaction of allenylnitriles with imines using chiral bis(imidazoline)s palladium(II) pincer
complexes. Angew Chem Int Ed 56:8677–8680
71. Hyodo K, Nakamura S, Shibata N (2012) Enantioselective aza-Morita-Baylis-Hillman reactions of acrylonitrile catalyzed by palladium(II) pincer complexes having C2-symmetric chiral
bis(imidazoline) ligands. Angew Chem Int Ed 51:10337–10341
72. Nakamura S, Tokunaga A, Saito H, Kondo M (2019) Enantioselective conjugate addition of an
alpha,alpha-dithioacetonitrile with nitroalkenes using chiral bis(imidazoline)-Pd complexes.
Chem Commun 55:5391–5394
73. Seligson AL, Trogler WC (1993) Protonolysis approach to the catalytic amination of olefins
with bis(phosphine)palladium(II) dialkyls. Organometallics 12:744–751
74. Kawatsura M, Hartwig JF (2001) Transition metal-catalyzed addition of amines to acrylic acid
derivatives. A high-throughput method for evaluating hydroamination of primary and secondary alkylamines. Organometallics 20:1960–1964
75. Fadini L, Togni A (2003) Ni(II) complexes containing chiral tridentate phosphines as new
catalysts for the hydroamination of activated olefins. Chem Commun:30–31
76. Fadini L, Togni A (2007) Asymmetric catalytic hydroamination of activated olefins in ionic
liquids. HeIv Chim Acta 90:411–424
77. Fadini L, Togni A (2008) Asymmetric hydroamination of acrylonitrile derivatives catalyzed
by Ni(II)-complexes. Tetrahedron Asymmetry 19:2555–2562
78. Senn HM, Blöchl PE, Togni A (2000) Toward an alkene hydroamination catalyst: static and
dynamic ab initio DFT studies. J Am Chem Soc 122:4098–4107
79. Sadow AD, Haller I, Fadini L, Togni A (2004) Nickel(II)-catalyzed highly enantioselective
hydrophosphination of methacrylonitrile. J Am Chem Soc 126:14704–14705
80. Sadow AD, Togni A (2005) Enantioselective addition of secondary phosphines to
methacrylonitrile: catalysis and mechanism. J Am Chem Soc 127:17012–17024
81. Pandarus V, Zargarian D (2007) New pincer-type diphosphinito (POCOP) complexes of
nickel. Organometallics 26:4321–4334
82. Castonguay A, Spasyuk DM, Madern N, Beauchamp AL, Zargarian D (2009) Regioselective
hydroamination of acrylonitrile catalyzed by cationic pincer complexes of nickel(II). Organometallics 28:2134–2141
83. Spasyuk DM, Zargarian D (2010) Monomeric and dimeric nickel complexes derived from a
pincer ligand featuring a secondary amine donor moiety. Inorg Chem 49:6203–6213
84. Lefèvre X, Durieux G, Lesturgez S, Zargarian D (2011) Addition of amines and phenols to
acrylonitrile derivatives catalyzed by the POCOP-type pincer complex [{κP,κC,κP-2,6(i-Pr 2 PO) 2 C 6 H 3 }Ni(NCMe)][OSO 2 CF 3 ]. J Mol Catal A Chem 335:1–7
376
B. Guo et al.
complex for catalytic asymmetric mannich reaction of malononitrile with N-Boc imines.
Chem Eur J 21:10671–10675
65. Hyodo K, Nakamura S, Tsuji K, Ogawa T, Funahashi Y, Shibata N (2011) Enantioselective
reaction of imines and benzyl nitriles using palladium pincer complexes with C2-symmetric
chiral bis(imidazoline)s. Adv Synth Catal 353:3385–3390
66. Hyodo K, Kondo M, Funahashi Y, Nakamura S (2013) Catalytic enantioselective
decarboxylative cyanoalkylation of imines by using palladium pincer complexes with
C2-symmetric chiral bis(imidazoline)s. Chem Eur J 19:4128–4134
67. Kondo M, Kobayashi N, Hatanaka T, Funahashi Y, Nakamura S (2015) Catalytic
enantioselective reaction of alpha-phenylthioacetonitriles with imines using chiral bis
(imidazoline)-palladium catalysts. Chem Eur J 21:9066–9070
68. Kondo M, Nishi T, Hatanaka T, Funahashi Y, Nakamura S (2015) Catalytic enantioselective
reaction of alpha-aminoacetonitriles using chiral bis(imidazoline) palladium catalysts. Angew
Chem Int Ed 54:8198–8202
69. Kondo M, Sugimoto M, Nakamura S (2016) Direct catalytic enantioselective Mannich-type
reaction of dichloroacetonitrile using bis(imidazoline)-Pd catalysts. Chem Commun
52:13604–13607
70. Kondo M, Omori M, Hatanaka T, Funahashi Y, Nakamura S (2017) Catalytic enantioselective
reaction of allenylnitriles with imines using chiral bis(imidazoline)s palladium(II) pincer
complexes. Angew Chem Int Ed 56:8677–8680
71. Hyodo K, Nakamura S, Shibata N (2012) Enantioselective aza-Morita-Baylis-Hillman reactions of acrylonitrile catalyzed by palladium(II) pincer complexes having C2-symmetric chiral
bis(imidazoline) ligands. Angew Chem Int Ed 51:10337–10341
72. Nakamura S, Tokunaga A, Saito H, Kondo M (2019) Enantioselective conjugate addition of an
alpha,alpha-dithioacetonitrile with nitroalkenes using chiral bis(imidazoline)-Pd complexes.
Chem Commun 55:5391–5394
73. Seligson AL, Trogler WC (1993) Protonolysis approach to the catalytic amination of olefins
with bis(phosphine)palladium(II) dialkyls. Organometallics 12:744–751
74. Kawatsura M, Hartwig JF (2001) Transition metal-catalyzed addition of amines to acrylic acid
derivatives. A high-throughput method for evaluating hydroamination of primary and secondary alkylamines. Organometallics 20:1960–1964
75. Fadini L, Togni A (2003) Ni(II) complexes containing chiral tridentate phosphines as new
catalysts for the hydroamination of activated olefins. Chem Commun:30–31
76. Fadini L, Togni A (2007) Asymmetric catalytic hydroamination of activated olefins in ionic
liquids. HeIv Chim Acta 90:411–424
77. Fadini L, Togni A (2008) Asymmetric hydroamination of acrylonitrile derivatives catalyzed
by Ni(II)-complexes. Tetrahedron Asymmetry 19:2555–2562
78. Senn HM, Blöchl PE, Togni A (2000) Toward an alkene hydroamination catalyst: static and
dynamic ab initio DFT studies. J Am Chem Soc 122:4098–4107
79. Sadow AD, Haller I, Fadini L, Togni A (2004) Nickel(II)-catalyzed highly enantioselective
hydrophosphination of methacrylonitrile. J Am Chem Soc 126:14704–14705
80. Sadow AD, Togni A (2005) Enantioselective addition of secondary phosphines to
methacrylonitrile: catalysis and mechanism. J Am Chem Soc 127:17012–17024
81. Pandarus V, Zargarian D (2007) New pincer-type diphosphinito (POCOP) complexes of
nickel. Organometallics 26:4321–4334
82. Castonguay A, Spasyuk DM, Madern N, Beauchamp AL, Zargarian D (2009) Regioselective
hydroamination of acrylonitrile catalyzed by cationic pincer complexes of nickel(II). Organometallics 28:2134–2141
83. Spasyuk DM, Zargarian D (2010) Monomeric and dimeric nickel complexes derived from a
pincer ligand featuring a secondary amine donor moiety. Inorg Chem 49:6203–6213
84. Lefèvre X, Durieux G, Lesturgez S, Zargarian D (2011) Addition of amines and phenols to
acrylonitrile derivatives catalyzed by the POCOP-type pincer complex [{κP,κC,κP-2,6(i-Pr 2 PO) 2 C 6 H 3 }Ni(NCMe)][OSO 2 CF 3 ]. J Mol Catal A Chem 335:1–7
376
B. Guo et al.