16. Fonseca F, Obert JP, Be ´al C, Marin M (2001)
State diagrams and sorption isotherms of bacterial suspensions and fermented medium.
Thermochim Acta 366:167–182
17. Ablett S, Izzard MJ, Lillford PJ (1992) Differential scanning calorimetric study of frozen
sucrose and glycerol solutions. J Chem Soc
Faraday Trans 88:789–794
18. Shalaev EY, Franks F (1995) Structural glass
transitions and thermophysical processes in
amorphous carbohydrates and their supersaturated solutions. J Chem Soc Faraday Trans
91:1511–1517
19. Scutella B, Bourles E, Plana-Fattori A,
Fonseca F, Flick D, Trelea I-C, Passot S
(2018) Effect of freeze dryer design on heat
transfer variability investigated using a 3D
mathematical
model.
J
Pharm
Sci
107:2098–2106
20. Scutella ` B, Plana-Fattori A, Passot S, Bourles E,
Fonseca F, Flick D, Trelea IC (2017) 3D mathematical modelling to understand atypical heat
transfer observed in vial freeze-drying. Appl
Therm Eng 126:226–236
21. Trelea IC, Passot S, Fonseca F, Marin M
(2007) An interactive tool for the optimization
of freeze-drying cycles based on quality criteria.
Dry Technol 25:741–751
22. Trelea IC, Guillemin H (2009) LyOptM v.3:
an interactive tool for freeze-drying cycle optimisation based on product quality criteria
IDDN.FR.001.100008.000.R.
P.2009.000.20700. UMR GMPA, Grignon
Physical Properties and Freeze-Drying of Bacteria
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