recrystallization inhibitors improve the postthaw function of hematopoietic stem and progenitor cells. ACS Omega 1:1010–1018
10. Briard JG, Poisosn JS, Turner TR, Capiccioti
CJ, Acker JP, Ben RN (2016) Small molecule
ice recrystallization inhibitors mitigate red
blood cell lysis during freezing, transient
warming and thawing. Sci Rep 6:23619
11. Capicciotti C, Kurach J, Turner T, Mancini R,
Acker J, Ben R (2015) Small molecule ice
recrystallization inhibitors enable freezing of
human red blood cells with reduced glycerol
concentrations. Sci Rep 5:9692
12. Capicciotti C, Poisson J, Boddy C, Ben R
(2015) Modulation of antifreeze activity and
the effect upon post-thaw HepG2 cell viability
after cryopreservation. Cryobiology 70:79–89
13. Leclere M, Kwok B, Wu L, Allan D, Ben R
(2011) C-linked antifreeze glycoprotein
(C-AFGP) analogues as novel cryoprotectants.
Bioconjug Chem 22:1804–1810
14. Poisson J, Briard J, Turner T, Acker J, Ben R
(2017) Hydroxyethyl starch supplemented
with ice recrystallization inhibitors greatly
improves cryopreservation of human red
blood cells. Bioprocess J 15:16–21
15. Deller R, Vatish M, Mitchell D, Gibson M
(2015) Glycerol-free cryopreservation of red
blood cells enabled by ice recrystallization inhibiting polymers. ACS Biomater Sci Eng
1:789–794
16. Jeon SM, Naing AH, Park KI, Kim CK (2015)
The effect of antifreeze protein on the cryopreservation of chrysanthemums. Plant Cell
Tissue Organ Cult 13:375–402
17. Mitchell D, Cameron N, Gibson M (2015)
Rational, yet simple, design and synthesis of
an antifreeze-protein inspired polymer for cellular cryopreservation. Chem Commun
51:12977–12980
18. Blau H, Daley G (2019) Stem cells in the treatment of disease. N Engl J Med
380:1748–1760
19. Damodaran S (2007) Inhibition of ice crystal
growth in ice cream mix by gelatin hydrolysate.
J Agric Food Chem 55:10918–10923
20. Payne S, Sandford D, Harris A, Young O
(1994) The effects of antifreeze proteins on
chilled and frozen meat. Science 37:429–438
21. Warren C, Mueller C, Mckown R (1992) Ice
crystal growth suppression polypeptides and
methods of preparation. USA patent:
US5118792A
22. Griffith M, Ewart K (1995) Antifreeze proteins
and their potential use in frozen foods. Biotechnol Adv 13:375–402
23. Scholander P, van Dam L, Kanwisher J,
Hammel H, Gordon M (1957) Supercooling
and osmoregulation in arctic fish. J Cell Comp
Physiol 49:5–24
24. Gordon M, Amdur B, Scholander P (1962)
Freezing resistance in some northern fishes.
Biol Bull 122:52–62
25. Devries AL (1971) Glycoproteins as biological
antifreeze agents in Antarctic fishes. Science
172:1152–1155
26. Cheng C, Chen L, Near T, Jin Y (2003) Functional antifreeze glycoprotein genes in
temperate-water New Zealand Nototheniid
fish infer an Antarctic evolutionary origin.
Mol Bio Evol 20:1897–1908
27. Harding M, Anderberg P, Haymet A (2003)
Antifreeze glycoproteins from polar fish. Eur J
Biochem 270:1381–1392
28. Griffith M, Antikainen M, Hon W-C, Pihakaski-Maunsbach K, Yu XM, Chun J, Yang D
(1997) Antifreeze proteins in winter rye.
Physiol Plant 100:327–332
29. Dunamn J, Horwarth K, Tomchaney A, Patterson J (1982) Antifreeze agents of terrestrial
arthropods.
Comp
Biochem
Physiol
73:545–555
30. Lee J, Park K, Park S, Park H, Song Y, Kang
SH, Kim H (2010) An extracellular ice-binding
glycoprotein from an Arctic psychrophilic
yeast. Cryobiology 60:222–228
31. Sun X, Griffith M, Pasternak J, Glick B (1995)
Low temperature growth, freezing survival,
and production of antifreeze protein by the
plant growth promoting rhizobacterium Pseudomonas putida GR12-2. Can J Microbiol
41:776–784
32. Anisuzzaman A, Anderson L, Navia J (1988)
Synthesis of a close analog of the repeating unit
of the antifreeze glycoproteins of polar fish.
Carbohydr Res 174:265–278
33. Ben R, Eniade A, Haur L (1999) Synthesis of a
C-linked antifreeze glycoprotein (AFGP)
mimic: probes for investigating the mechanism
of action. Org Lett 1:1759–1762
34. Eniade A, Purushotham M, Ben R (2003) A
serendipitous discovery of antifreeze proteinspecific activity in C-linked antifreeze glycoprotein analogues. Cell Biochem Biophys
38:115–124
35. Filira F, Biondi L, Scolaro B, Foffani M,
Mammi S, Peggion E, Rocchi P (1990) Solid
phase synthesis and conformation of sequential
glycosylated polytripeptide sequences related
to antifreeze glycoproteins. Int J Biol Macromol 12:41–49
36. Liu S, Wang W, von Moos E, Jackman J,
Mealing G, Monette R, Ben R (2007) In vitro
Ice Recrystallization Inhibition Assays
281
10. Briard JG, Poisosn JS, Turner TR, Capiccioti
CJ, Acker JP, Ben RN (2016) Small molecule
ice recrystallization inhibitors mitigate red
blood cell lysis during freezing, transient
warming and thawing. Sci Rep 6:23619
11. Capicciotti C, Kurach J, Turner T, Mancini R,
Acker J, Ben R (2015) Small molecule ice
recrystallization inhibitors enable freezing of
human red blood cells with reduced glycerol
concentrations. Sci Rep 5:9692
12. Capicciotti C, Poisson J, Boddy C, Ben R
(2015) Modulation of antifreeze activity and
the effect upon post-thaw HepG2 cell viability
after cryopreservation. Cryobiology 70:79–89
13. Leclere M, Kwok B, Wu L, Allan D, Ben R
(2011) C-linked antifreeze glycoprotein
(C-AFGP) analogues as novel cryoprotectants.
Bioconjug Chem 22:1804–1810
14. Poisson J, Briard J, Turner T, Acker J, Ben R
(2017) Hydroxyethyl starch supplemented
with ice recrystallization inhibitors greatly
improves cryopreservation of human red
blood cells. Bioprocess J 15:16–21
15. Deller R, Vatish M, Mitchell D, Gibson M
(2015) Glycerol-free cryopreservation of red
blood cells enabled by ice recrystallization inhibiting polymers. ACS Biomater Sci Eng
1:789–794
16. Jeon SM, Naing AH, Park KI, Kim CK (2015)
The effect of antifreeze protein on the cryopreservation of chrysanthemums. Plant Cell
Tissue Organ Cult 13:375–402
17. Mitchell D, Cameron N, Gibson M (2015)
Rational, yet simple, design and synthesis of
an antifreeze-protein inspired polymer for cellular cryopreservation. Chem Commun
51:12977–12980
18. Blau H, Daley G (2019) Stem cells in the treatment of disease. N Engl J Med
380:1748–1760
19. Damodaran S (2007) Inhibition of ice crystal
growth in ice cream mix by gelatin hydrolysate.
J Agric Food Chem 55:10918–10923
20. Payne S, Sandford D, Harris A, Young O
(1994) The effects of antifreeze proteins on
chilled and frozen meat. Science 37:429–438
21. Warren C, Mueller C, Mckown R (1992) Ice
crystal growth suppression polypeptides and
methods of preparation. USA patent:
US5118792A
22. Griffith M, Ewart K (1995) Antifreeze proteins
and their potential use in frozen foods. Biotechnol Adv 13:375–402
23. Scholander P, van Dam L, Kanwisher J,
Hammel H, Gordon M (1957) Supercooling
and osmoregulation in arctic fish. J Cell Comp
Physiol 49:5–24
24. Gordon M, Amdur B, Scholander P (1962)
Freezing resistance in some northern fishes.
Biol Bull 122:52–62
25. Devries AL (1971) Glycoproteins as biological
antifreeze agents in Antarctic fishes. Science
172:1152–1155
26. Cheng C, Chen L, Near T, Jin Y (2003) Functional antifreeze glycoprotein genes in
temperate-water New Zealand Nototheniid
fish infer an Antarctic evolutionary origin.
Mol Bio Evol 20:1897–1908
27. Harding M, Anderberg P, Haymet A (2003)
Antifreeze glycoproteins from polar fish. Eur J
Biochem 270:1381–1392
28. Griffith M, Antikainen M, Hon W-C, Pihakaski-Maunsbach K, Yu XM, Chun J, Yang D
(1997) Antifreeze proteins in winter rye.
Physiol Plant 100:327–332
29. Dunamn J, Horwarth K, Tomchaney A, Patterson J (1982) Antifreeze agents of terrestrial
arthropods.
Comp
Biochem
Physiol
73:545–555
30. Lee J, Park K, Park S, Park H, Song Y, Kang
SH, Kim H (2010) An extracellular ice-binding
glycoprotein from an Arctic psychrophilic
yeast. Cryobiology 60:222–228
31. Sun X, Griffith M, Pasternak J, Glick B (1995)
Low temperature growth, freezing survival,
and production of antifreeze protein by the
plant growth promoting rhizobacterium Pseudomonas putida GR12-2. Can J Microbiol
41:776–784
32. Anisuzzaman A, Anderson L, Navia J (1988)
Synthesis of a close analog of the repeating unit
of the antifreeze glycoproteins of polar fish.
Carbohydr Res 174:265–278
33. Ben R, Eniade A, Haur L (1999) Synthesis of a
C-linked antifreeze glycoprotein (AFGP)
mimic: probes for investigating the mechanism
of action. Org Lett 1:1759–1762
34. Eniade A, Purushotham M, Ben R (2003) A
serendipitous discovery of antifreeze proteinspecific activity in C-linked antifreeze glycoprotein analogues. Cell Biochem Biophys
38:115–124
35. Filira F, Biondi L, Scolaro B, Foffani M,
Mammi S, Peggion E, Rocchi P (1990) Solid
phase synthesis and conformation of sequential
glycosylated polytripeptide sequences related
to antifreeze glycoproteins. Int J Biol Macromol 12:41–49
36. Liu S, Wang W, von Moos E, Jackman J,
Mealing G, Monette R, Ben R (2007) In vitro
Ice Recrystallization Inhibition Assays
281