Index
331
L
Lautenberg Act, 41
Law for Pollutant Release and Transfer
Register and Promotion of Chemical
Management (PRTR Law), 42
Legislation, 27
Life cycle assessment (LCA), 67
Life cycle costing (LCC), 67, 99
Life cycle impact assessment (LCIA), 80
Life cycle inventory, 71
Life cycle sustainability assessment (LCSA),
67
Long-range transport potential (LRTP), 131
Loss event, 161
Low-dose effects, 142
Lower flammability limit, 177
Lowest observed adverse effect level
(LOAEL), 140
Lowest observed effect concentration (LOEC),
141
M
Macro-calorimetry, 298
Major-accident prevention policy (MAPP), 46
Margin of safety (MOS), 142, 143
Matrix inversion method, 77
Maximum immission concentration (MIC),
141
Maximum residue levels (MRLs), 40
Maximum residue limits (MRLs), 255
Maximum temperature of the synthesis
reaction (MTSR), 207
Mean time between failures (MTBF), 289
Micro-calorimetry, 298
Midpoint, 82
Minamata convention, 57
Minimum ignition energy, 272
Mixture toxicity, 40, 145
Mode of action, 136
Montreal protocol, 44
Multi-criteria decision analysis (MCDA), 90
Multimedia mass-balance models, 127
Mutagenesis, 136
Mutagenicity, 111
N
Net present value (NPV), 96
No observed adverse effect level (NOAEL),
140
No observed effect concentration (NOEC),
113, 141
Normalization, 88
O
Occupational exposure limits (OELs), 47
Occupational safety and health directives
(OSH), 46
Opinions, 28
Overall persistence (Pov), 131
P
Passive transport, 134
Peak concentrations, 123
Persistence, 131
Persistent, bioaccumulative, and toxic (PBT),
34
Pesticides, 37
Photochemical ozone creation, 87
Photolysis, 268
Phthalates, 118
Physiologically based pharmacokinetic models
(PBPK models), 135
Poisonous and deleterious substances control
law (PDSCL), 42
Precautionary principle, 14, 30, 131
Predicted daily intake (PDI), 115
Predicted environmental concentration (PEC),
109, 123
Predicted no-effect concentration (PNEC),
109, 133, 140
Preliminary hazard analysis, 169
Pre-manufacture notice (PMN), 41
Primary energy, 85
Probabilistic risk assessment (PRA), 14
Probability analysis, 174
Probability of failure on demand (PFD), 290
Probit method, 177
Process deviation, 161
Process hazards, 161
Process risk assessment, 68, 159
Process tree, 72
Product flows, 71
Product risk assessment, 68, 108
Protected good, 10
Protection layers, 162
Q
Quantitative structure-activity relationships
(QSARs), 133
R
Read-across, 133
Recommendations, 28
Recursive processes, 76
331
L
Lautenberg Act, 41
Law for Pollutant Release and Transfer
Register and Promotion of Chemical
Management (PRTR Law), 42
Legislation, 27
Life cycle assessment (LCA), 67
Life cycle costing (LCC), 67, 99
Life cycle impact assessment (LCIA), 80
Life cycle inventory, 71
Life cycle sustainability assessment (LCSA),
67
Long-range transport potential (LRTP), 131
Loss event, 161
Low-dose effects, 142
Lower flammability limit, 177
Lowest observed adverse effect level
(LOAEL), 140
Lowest observed effect concentration (LOEC),
141
M
Macro-calorimetry, 298
Major-accident prevention policy (MAPP), 46
Margin of safety (MOS), 142, 143
Matrix inversion method, 77
Maximum immission concentration (MIC),
141
Maximum residue levels (MRLs), 40
Maximum residue limits (MRLs), 255
Maximum temperature of the synthesis
reaction (MTSR), 207
Mean time between failures (MTBF), 289
Micro-calorimetry, 298
Midpoint, 82
Minamata convention, 57
Minimum ignition energy, 272
Mixture toxicity, 40, 145
Mode of action, 136
Montreal protocol, 44
Multi-criteria decision analysis (MCDA), 90
Multimedia mass-balance models, 127
Mutagenesis, 136
Mutagenicity, 111
N
Net present value (NPV), 96
No observed adverse effect level (NOAEL),
140
No observed effect concentration (NOEC),
113, 141
Normalization, 88
O
Occupational exposure limits (OELs), 47
Occupational safety and health directives
(OSH), 46
Opinions, 28
Overall persistence (Pov), 131
P
Passive transport, 134
Peak concentrations, 123
Persistence, 131
Persistent, bioaccumulative, and toxic (PBT),
34
Pesticides, 37
Photochemical ozone creation, 87
Photolysis, 268
Phthalates, 118
Physiologically based pharmacokinetic models
(PBPK models), 135
Poisonous and deleterious substances control
law (PDSCL), 42
Precautionary principle, 14, 30, 131
Predicted daily intake (PDI), 115
Predicted environmental concentration (PEC),
109, 123
Predicted no-effect concentration (PNEC),
109, 133, 140
Preliminary hazard analysis, 169
Pre-manufacture notice (PMN), 41
Primary energy, 85
Probabilistic risk assessment (PRA), 14
Probability analysis, 174
Probability of failure on demand (PFD), 290
Probit method, 177
Process deviation, 161
Process hazards, 161
Process risk assessment, 68, 159
Process tree, 72
Product flows, 71
Product risk assessment, 68, 108
Protected good, 10
Protection layers, 162
Q
Quantitative structure-activity relationships
(QSARs), 133
R
Read-across, 133
Recommendations, 28
Recursive processes, 76