References
319
• Occupational risk: (1) The report detailing the development and use of
the EFSA tool (EFSA, 2014) should be reviewed to fully understand the
assumptions made by the model used. (2) Assumed input data such as
absorption levels for ASM may be more accurately refined through a review
of recent information.
• Dietary risk: (1) Just a small subset of selected foods was investigated. Total
dietary exposure should take into account all residues that could exist on
foods within the diet. From the calculated margin of safety, a 24-fold higher
dietary exposure would be required before the ADI is exceeded. (2) The
calculations assumed that the maximum amount of the MRL was present
on all samples (a worst-case scenario).
References
Atherton J, Gil F (2008) Incidents That Define Process Safety. John Wiley & Sons, Inc., Hoboken,
NJ, USA, http://doi.wiley.com/10.1002/9780470925171
Anastassiadou M, Brancato A, Carrasco Cabrera L, Ferreira L, Greco L, Jarrah S, Kazocina A,
Leuschner R, Magrans JO, Miron I, Pedersen R, Raczyk M, Reich H, Ruocco S, Sacchi A,
Santos M, Stanek A, Tarazona J, Theobald A, Verani A (2019) Pesticide Residue Intake ModelEFSA PRIMo revision 3.1. EFSA Supporting Publications 16(3):1–15, https://doi.org/10.2903/
sp.efsa.2019.EN-1605, http://doi.wiley.com/10.2903/sp.efsa.2019.EN-1605
CCPS (1999) Guidelines for Chemical Process Quantitative Risk Analysis, 2nd edn. John Wiley
& Sons, Inc., https://www.wiley.com/en-us/Guidelines+for+Chemical+Process+Quantitative+
Risk+Analysis%2C+2nd+Edition-p-9780816907205
CPD (1996) Methods for the calculation of Physical Effects. Tech. rep., http://content.
publicatiereeksgevaarlijkestoffen.nl/documents/PGS2/PGS2-1997-v0.1-physical-effects.pdf
ECHA (2019a) Brief Profile: S-methyl benzo(1.2.3)thiadiazole-7-carbothioate. https://echa.
europa.eu/brief-profile/-/briefprofile/100.101.876
ECHA (2019b) Hydrogen cyanide: Guidance of Safe Use. https://echa.europa.eu/registrationdossier/-/registered-dossier/14996/9
EFSA (2014) Conclusion on the peer review of the pesticide risk assessment of the active
substance acibenzolar-S-methyl. EFSA Journal 12(8):3691, http://doi.wiley.com/10.2903/j.efsa.
2014.3691
EFSA (2019) Pesticides. https://www.efsa.europa.eu/en/topics/topic/pesticides
Elvers B (ed) (2000) Ullmann’s Encyclopedia of Industrial Chemistry. Wiley, Weinheim, Germany,
http://doi.wiley.com/10.1002/14356007
ESCIS (1994) Inerting: Methods and Measures for the Avoidance of lgnitable Substance-Air
Mixtures in Chemical Production Equipment and Plants. ESCIS Safety Series 3, https://doi.
org/10.3929/ETHZ-B-000354483
European Commission (2019a) EU Pesticides Database. http://ec.europa.eu/food/plant/pesticides/
eu-pesticides-database/public/?event=homepage&language=EN
European Commission (2019b) Pesticides. https://ec.europa.eu/food/plant/pesticides_en
Gygax R (1993) Thermal Process Safety. ESCIS Safety Series 8, https://doi.org/10.3929/ETHZB-000354503
IEC (2017) IEC 60079-0. http://dom1.iec.ch/publication/62232
Jacob DJ (1999) Introduction to Atmospheric Chemistry. Princeton University Press, https://press.
princeton.edu/books/hardcover/9780691001852/introduction-to-atmospheric-chemistry http://
acmg.seas.harvard.edu/people/faculty/djj/book/
Stoessel F (2008) Thermal Safety of Chemical Processes. Wiley-VCH Verlag GmbH & Co. KGaA,
Weinheim, Germany, http://doi.wiley.com/10.1002/9783527621606
319
• Occupational risk: (1) The report detailing the development and use of
the EFSA tool (EFSA, 2014) should be reviewed to fully understand the
assumptions made by the model used. (2) Assumed input data such as
absorption levels for ASM may be more accurately refined through a review
of recent information.
• Dietary risk: (1) Just a small subset of selected foods was investigated. Total
dietary exposure should take into account all residues that could exist on
foods within the diet. From the calculated margin of safety, a 24-fold higher
dietary exposure would be required before the ADI is exceeded. (2) The
calculations assumed that the maximum amount of the MRL was present
on all samples (a worst-case scenario).
References
Atherton J, Gil F (2008) Incidents That Define Process Safety. John Wiley & Sons, Inc., Hoboken,
NJ, USA, http://doi.wiley.com/10.1002/9780470925171
Anastassiadou M, Brancato A, Carrasco Cabrera L, Ferreira L, Greco L, Jarrah S, Kazocina A,
Leuschner R, Magrans JO, Miron I, Pedersen R, Raczyk M, Reich H, Ruocco S, Sacchi A,
Santos M, Stanek A, Tarazona J, Theobald A, Verani A (2019) Pesticide Residue Intake ModelEFSA PRIMo revision 3.1. EFSA Supporting Publications 16(3):1–15, https://doi.org/10.2903/
sp.efsa.2019.EN-1605, http://doi.wiley.com/10.2903/sp.efsa.2019.EN-1605
CCPS (1999) Guidelines for Chemical Process Quantitative Risk Analysis, 2nd edn. John Wiley
& Sons, Inc., https://www.wiley.com/en-us/Guidelines+for+Chemical+Process+Quantitative+
Risk+Analysis%2C+2nd+Edition-p-9780816907205
CPD (1996) Methods for the calculation of Physical Effects. Tech. rep., http://content.
publicatiereeksgevaarlijkestoffen.nl/documents/PGS2/PGS2-1997-v0.1-physical-effects.pdf
ECHA (2019a) Brief Profile: S-methyl benzo(1.2.3)thiadiazole-7-carbothioate. https://echa.
europa.eu/brief-profile/-/briefprofile/100.101.876
ECHA (2019b) Hydrogen cyanide: Guidance of Safe Use. https://echa.europa.eu/registrationdossier/-/registered-dossier/14996/9
EFSA (2014) Conclusion on the peer review of the pesticide risk assessment of the active
substance acibenzolar-S-methyl. EFSA Journal 12(8):3691, http://doi.wiley.com/10.2903/j.efsa.
2014.3691
EFSA (2019) Pesticides. https://www.efsa.europa.eu/en/topics/topic/pesticides
Elvers B (ed) (2000) Ullmann’s Encyclopedia of Industrial Chemistry. Wiley, Weinheim, Germany,
http://doi.wiley.com/10.1002/14356007
ESCIS (1994) Inerting: Methods and Measures for the Avoidance of lgnitable Substance-Air
Mixtures in Chemical Production Equipment and Plants. ESCIS Safety Series 3, https://doi.
org/10.3929/ETHZ-B-000354483
European Commission (2019a) EU Pesticides Database. http://ec.europa.eu/food/plant/pesticides/
eu-pesticides-database/public/?event=homepage&language=EN
European Commission (2019b) Pesticides. https://ec.europa.eu/food/plant/pesticides_en
Gygax R (1993) Thermal Process Safety. ESCIS Safety Series 8, https://doi.org/10.3929/ETHZB-000354503
IEC (2017) IEC 60079-0. http://dom1.iec.ch/publication/62232
Jacob DJ (1999) Introduction to Atmospheric Chemistry. Princeton University Press, https://press.
princeton.edu/books/hardcover/9780691001852/introduction-to-atmospheric-chemistry http://
acmg.seas.harvard.edu/people/faculty/djj/book/
Stoessel F (2008) Thermal Safety of Chemical Processes. Wiley-VCH Verlag GmbH & Co. KGaA,
Weinheim, Germany, http://doi.wiley.com/10.1002/9783527621606