25. Investigating the release at pH 1.2 could be conducted to
mimic the drug release while passing the stomach en route to
the colon to confirm the balanced release of the drug.
References
1. Tiwari G, Tiwari R, Sriwastawa B et al (2012)
Drug delivery systems: an updated review. Int J
Pharm Investig 2(1):2
2. Ratnaparkhi MP, Somvanshi FU, Pawar SA
et al (2013) Colon targeted drug delivery system. Int J Pharm Rev Res 2(8):33–42
3. Jose S, Dhanya K, Cinu T et al (2009) Colon
targeted drug delivery: different approaches. J
Young Pharm 1(1):13
4. Amidon S, Brown JE, Dave VS (2015) Colontargeted oral drug delivery systems: design
trends and approaches. AAPS PharmSciTech
16(4):731–741
5. Pushpamalar J, Veeramachineni A, Owh C et al
(2016) Biodegradable polysaccharides for controlled drug delivery. ChemPlusChem
81:504–514
6. Li J, Mooney DJ (2016) Designing hydrogels
for controlled drug delivery. Nat Rev Mater 1
(12):16071
7. Thenapakiam S, Kumar DG, Pushpamalar J
et al (2013) Aluminium and radiation crosslinked carboxymethyl sago pulp beads for
colon targeted delivery. Carbohydr Polym 94
(1):356–363
8. Sathasivam T, Muniyandy S, Chuah LH et al
(2018) Encapsulation of red palm oil in
carboxymethyl sago cellulose beads by emulsification and vibration technology: physicochemical characterization and in vitro
digestion. J Food Eng 231:10–21
9. Lyn Heng J, Teng J, Saravanan M et al (2018)
Influence of Ispaghula and Zein coating on
ibuprofen-loaded alginate beads prepared by
vibration technology: physicochemical characterization and release studies. Sci Pharm 86
(2):24
10. Tan HL, Tan LS, Wong YY et al (2016) Dual
crosslinked carboxymethyl sago pulp/pectin
hydrogel beads as potential carrier for colontargeted drug delivery. J Appl Polym 133
(19):43416
11. Huei GOS, Muniyandy S, Sathasivam T et al
(2016) Iron cross-linked carboxymethyl cellulose–gelatin complex coacervate beads for sustained drug delivery. Chem Papers 70
(2):243–252
12. Veeramachineni AK, Sathasivam T, Paramasivam R et al (2019) Synthesis and characterization of a novel pH-sensitive aluminum
crosslinked carboxymethyl tragacanth beads
for extended and enteric drug delivery. J
Polym Environ 27(7):1516–1528
182
Janarthanan Pushpamalar et al.
mimic the drug release while passing the stomach en route to
the colon to confirm the balanced release of the drug.
References
1. Tiwari G, Tiwari R, Sriwastawa B et al (2012)
Drug delivery systems: an updated review. Int J
Pharm Investig 2(1):2
2. Ratnaparkhi MP, Somvanshi FU, Pawar SA
et al (2013) Colon targeted drug delivery system. Int J Pharm Rev Res 2(8):33–42
3. Jose S, Dhanya K, Cinu T et al (2009) Colon
targeted drug delivery: different approaches. J
Young Pharm 1(1):13
4. Amidon S, Brown JE, Dave VS (2015) Colontargeted oral drug delivery systems: design
trends and approaches. AAPS PharmSciTech
16(4):731–741
5. Pushpamalar J, Veeramachineni A, Owh C et al
(2016) Biodegradable polysaccharides for controlled drug delivery. ChemPlusChem
81:504–514
6. Li J, Mooney DJ (2016) Designing hydrogels
for controlled drug delivery. Nat Rev Mater 1
(12):16071
7. Thenapakiam S, Kumar DG, Pushpamalar J
et al (2013) Aluminium and radiation crosslinked carboxymethyl sago pulp beads for
colon targeted delivery. Carbohydr Polym 94
(1):356–363
8. Sathasivam T, Muniyandy S, Chuah LH et al
(2018) Encapsulation of red palm oil in
carboxymethyl sago cellulose beads by emulsification and vibration technology: physicochemical characterization and in vitro
digestion. J Food Eng 231:10–21
9. Lyn Heng J, Teng J, Saravanan M et al (2018)
Influence of Ispaghula and Zein coating on
ibuprofen-loaded alginate beads prepared by
vibration technology: physicochemical characterization and release studies. Sci Pharm 86
(2):24
10. Tan HL, Tan LS, Wong YY et al (2016) Dual
crosslinked carboxymethyl sago pulp/pectin
hydrogel beads as potential carrier for colontargeted drug delivery. J Appl Polym 133
(19):43416
11. Huei GOS, Muniyandy S, Sathasivam T et al
(2016) Iron cross-linked carboxymethyl cellulose–gelatin complex coacervate beads for sustained drug delivery. Chem Papers 70
(2):243–252
12. Veeramachineni AK, Sathasivam T, Paramasivam R et al (2019) Synthesis and characterization of a novel pH-sensitive aluminum
crosslinked carboxymethyl tragacanth beads
for extended and enteric drug delivery. J
Polym Environ 27(7):1516–1528
182
Janarthanan Pushpamalar et al.