2 Frustrated Lewis Pair Catalyzed Asymmetric Reactions
79
Table 2.38 Catalytic amination of different pro-nucleophiles
X
H
O
R
+
N
N
OMe
O
MeO
O
X
O
R
HN
N
COOMe
COOMe
B(C 6 F 5 ) 3
amine
81
82a
83
entry product
yield (%)
1
83a
HN
N
COOMe
COOMe
O
97
2
83b
HN
N
COOMe
COOMe
O
89
3
83c
Ph
O
Me
HN
N
COOMe
COOMe
98
4
83d
Ph
O HN
N
COOMe
COOMe
70
5
83e
HN
N
COOMe
COOMe
O
O
88
6
83f
HN
N
COOMe
COOMe
O
N
65
7
83g
HN
N
COOMe
COOMe
S
O
97
8
83h
HN
N
COOMe
COOMe
N
S
Me
98