66
X. Feng et al.
B
Ph
Ph
C 6 F 5
Sn
Ph
Ph
B
Ph
Ph
S
C 6 F 5
Me
Me
(S)-63⋅DMS
TMS
TMS
(C 6 F 5 )BCl 2
DMS
94%
53%
62
63
Scheme 2.17 Preparation of catalyst (S)-63·DMS
Table 2.27 Enantioselective carbonyl hydrosilylation
Ar
R
O
(S)-63 DMS (2.4 mol %)
PhSiH 3 (3.0 equiv)
Ar
R
OH
54
51
neat, rt
entry
product
yield (%) ee (%)
1
51a
Ph
Me
OH
62
93
2
51k
Me
OH
Br
78
99
3
51q
Me
OH
F 3 C
57
82
4
51r
Me
OH
Me
67
85
5
51s
Me
OH
Br
45
73
6
51t
Ph
Bn
OH
40
74
7
51u
Ph
OH
24
62
8
51v
Me
OH
77
80