microphase-separated, hydrophobically associating hydrogels and discusses their
potential applications. The preparation, structures, properties, and applications of
tough and responsive hydrogels cross-linked by triblock copolymer micelles are
reviewed in the chapter “Triblock Copolymer Micelle-Crosslinked Hydrogels.”
The micellar hydrogels show outstanding strength and toughness due to the
micelles serving as energy dissipation centers and exhibit good responsivity to
changes in pH, salt concentration, electric field, and temperature. Chapter “SelfHealing Hydrogels Based on Reversible Covalent Linkages: A Survey of Dynamic
Chemical Bonds in Network Formation” highlights, through examples, the synthesis and self-healing properties of hydrogels based on various types of reversible
dynamical cross-linking chemistries. The main focus of this chapter is on the
chemistry of cross-linking and the conditions under which self-healing can be
achieved.
Polyampholyte (OA) hydrogels have attracted great attention as innovative
materials due to their toughness and self-healing and viscoelatic behaviors. In the
chapter “Tough and Self-Healing Hydrogels from Polyampholytes,” the role of
dynamic ionic bonds on the mechanical, viscoelastic, and self-healing behavior of
PA hydrogels and their recent applications are discussed. Cellulose-based
hydrogels have emerged as promising materials for a wide range of applications
due to their inherently renewable, biocompatible, and biodegradable characteristics. Chapter “Dynamics in Cellulose-Based Hydrogels with Reversible CrossLinks” addresses the advances in the synthesis methods of such hydrogels from
native cellulose, cellulose derivatives, or composites and focuses on the design and
preparation of reversibly cross-linked cellulose-based hydrogels featuring a selfhealing or dynamic response to stimuli. Hydrogels derived from biopolymers such
as those made from collagen type I are very promising candidates for the repair of
nervous tissues due to their biocompatibility, noncytotoxic properties, injectability,
and self-healing ability. Chapter “Self-Healing Collagen-Based Hydrogel for Brain
Injury Therapy” reviews the most relevant results obtained from both in vitro and in
vivo studies using self-healing biohydrogels based on collagen type I as a key
component in the field of neuroregeneration.
The editors believe that the present volume will contribute a better understanding of the design and properties of self-healing/self-recovering hydrogels and their
potential application areas. We would like to thank all the authors who have
contributed to this exciting volume on self-healing/self-recovering hydrogels.
Paris, France
Costantino Creton
Istanbul, Turkey
Oguz Okay
vi
Preface
potential applications. The preparation, structures, properties, and applications of
tough and responsive hydrogels cross-linked by triblock copolymer micelles are
reviewed in the chapter “Triblock Copolymer Micelle-Crosslinked Hydrogels.”
The micellar hydrogels show outstanding strength and toughness due to the
micelles serving as energy dissipation centers and exhibit good responsivity to
changes in pH, salt concentration, electric field, and temperature. Chapter “SelfHealing Hydrogels Based on Reversible Covalent Linkages: A Survey of Dynamic
Chemical Bonds in Network Formation” highlights, through examples, the synthesis and self-healing properties of hydrogels based on various types of reversible
dynamical cross-linking chemistries. The main focus of this chapter is on the
chemistry of cross-linking and the conditions under which self-healing can be
achieved.
Polyampholyte (OA) hydrogels have attracted great attention as innovative
materials due to their toughness and self-healing and viscoelatic behaviors. In the
chapter “Tough and Self-Healing Hydrogels from Polyampholytes,” the role of
dynamic ionic bonds on the mechanical, viscoelastic, and self-healing behavior of
PA hydrogels and their recent applications are discussed. Cellulose-based
hydrogels have emerged as promising materials for a wide range of applications
due to their inherently renewable, biocompatible, and biodegradable characteristics. Chapter “Dynamics in Cellulose-Based Hydrogels with Reversible CrossLinks” addresses the advances in the synthesis methods of such hydrogels from
native cellulose, cellulose derivatives, or composites and focuses on the design and
preparation of reversibly cross-linked cellulose-based hydrogels featuring a selfhealing or dynamic response to stimuli. Hydrogels derived from biopolymers such
as those made from collagen type I are very promising candidates for the repair of
nervous tissues due to their biocompatibility, noncytotoxic properties, injectability,
and self-healing ability. Chapter “Self-Healing Collagen-Based Hydrogel for Brain
Injury Therapy” reviews the most relevant results obtained from both in vitro and in
vivo studies using self-healing biohydrogels based on collagen type I as a key
component in the field of neuroregeneration.
The editors believe that the present volume will contribute a better understanding of the design and properties of self-healing/self-recovering hydrogels and their
potential application areas. We would like to thank all the authors who have
contributed to this exciting volume on self-healing/self-recovering hydrogels.
Paris, France
Costantino Creton
Istanbul, Turkey
Oguz Okay
vi
Preface