12. Wu F, Chen L, Li Y, Lee KI, Fei B (2017) Super-tough hydrogels from shape-memory
polyurethane with wide-adjustable mechanical properties. J Mater Sci 52:4421–4434
13. Gong JP, Katsuyama Y, Kurokawa T, Osada Y (2003) Double-network hydrogels with
extremely high mechanical strength. Adv Mater 15:1155–1158
14. Tuncaboylu DC, Sarı M, Oppermann W, Okay O (2011) Tough and self-healing hydrogels
formed via hydrophobic interactions. Macromolecules 44:4997–5005
15. Uzumcu AT, Guney O, Okay O (2018) Highly stretchable DNA/clay hydrogels with selfhealing ability. ACS Appl Mater Interfaces 10:8296–8306
16. Hager MD, van der Zwaag S, Schubert US (eds) (2016) Self-healing materials. Adv Polym Sci
273. 413 pp
17. Taylor DL, in het Panhuis M (2016) Self-healing hydrogels. Adv Mater 28:9060–9093
18. Gyarmati B, Szilágyi BA, Szilágyi A (2017) Reversible interactions in self-healing and shape
memory hydrogels. Eur Polym J 93:642–669
19. Okay O (2015) Self-healing hydrogels formed via hydrophobic interactions. Adv Polym Sci
268:101–142
20. Okay O (2019) Semicrystalline physical hydrogels with shape-memory and self-healing
properties. J Mater Chem B 7:1581–1596
21. Talebian S, Mehrali M, Taebnia N, Pennisi CP, Kadumudi FB, Foroughi J, Hasany M,
Nikkhah M, Akbari M, Orive G, Dolatshahi-Pirouz A (2019) Self-healing hydrogels: the
next paradigm shift in tissue engineering? Adv Sci 6:1801664. (1–47)
22. Li Q, Liu C, Wen J, Wu Y, Shan Y, Liao J (2017) The design, mechanism and biomedical
application of self-healing hydrogels. Chin Chem Lett 28:1857–1874
23. Strandman S, Zhu XX (2016) Self-healing supramolecular hydrogels based on reversible
physical interactions. Gels 2:16. (1–31)
24. Wang W, Zhang Y, Liu W (2017) Bioinspired fabrication of high strength hydrogels from
non-covalent interactions. Prog Polym Sci 71:1–25
25. Sun TL, Kurokawa T, Kuroda S, Ihsan AB, Akasaki T, Sato K, Haque MA, Nakajima T, Gong
JP (2013) Physical hydrogels composed of polyampholytes demonstrate high toughness and
viscoelasticity. Nat Mater 12:932–937
26. Sun TL, Cui K (2020) Tough and self-healing hydrogels from polyampholytes. Adv Polym Sci
(in press), https://doi.org/10.1007/12_2019_56
27. Bilici C, Can V, Nöchel U, Behl M, Lendlein A, Okay O (2016) Melt-processable shapememory hydrogels with self-healing ability of high mechanical strength. Macromolecules
49:7442–7449
28. Su E, Okay O (2019) A self-healing and highly stretchable polyelectrolyte hydrogel via
cooperative hydrogen-bonding as a superabsorbent polymer. Macromolecules 52:3257–3267
29. Dai X, Zhang Y, Gao L, Bai T, Wang W, Cui Y, Liu W (2015) A mechanically strong, highly
stable, thermoplastic, and self-healable supramolecular polymer hydrogel. Adv Mater
27:3566–3571
30. Wang H, Zhu H, Fu W, Zhang Y, Xu B, Gao F, Cao Z, Liu W (2017) A high strength selfhealable antibacterial and anti-inflammatory supramolecular polymer hydrogel. Macromol
Rapid Commun 38:1600695
31. Tang L, Liu W, Liu G (2010) High-strength hydrogels with integrated functions of H-bonding
and thermoresponsive surface-mediated reverse transfection and cell detachment. Adv Mater
22:2652–2656
32. Gao H, Wang N, Hu X, Nan W, Han Y, Liu W (2013) Double hydrogen-bonding pH-sensitive
hydrogels retaining high-strengths over a wide pH range. Macromol Rapid Commun 34:63–68
33. Maly KE, Dauphin C, Wuest JD (2006) Self-assembly of columnar mesophases from
diaminotriazines. J Mater Chem 16:4695–4700
34. Liu B, Liu W (2018) Poly(vinyl diaminotriazine): from molecular recognition to high-strength
hydrogels. Macromol Rapid Commun 39:1800190
35. Sijbesma RP, Meijer EW (2003) Quadruple hydrogen bonded systems. Chem Commun:5–16
56
O. Okay
polyurethane with wide-adjustable mechanical properties. J Mater Sci 52:4421–4434
13. Gong JP, Katsuyama Y, Kurokawa T, Osada Y (2003) Double-network hydrogels with
extremely high mechanical strength. Adv Mater 15:1155–1158
14. Tuncaboylu DC, Sarı M, Oppermann W, Okay O (2011) Tough and self-healing hydrogels
formed via hydrophobic interactions. Macromolecules 44:4997–5005
15. Uzumcu AT, Guney O, Okay O (2018) Highly stretchable DNA/clay hydrogels with selfhealing ability. ACS Appl Mater Interfaces 10:8296–8306
16. Hager MD, van der Zwaag S, Schubert US (eds) (2016) Self-healing materials. Adv Polym Sci
273. 413 pp
17. Taylor DL, in het Panhuis M (2016) Self-healing hydrogels. Adv Mater 28:9060–9093
18. Gyarmati B, Szilágyi BA, Szilágyi A (2017) Reversible interactions in self-healing and shape
memory hydrogels. Eur Polym J 93:642–669
19. Okay O (2015) Self-healing hydrogels formed via hydrophobic interactions. Adv Polym Sci
268:101–142
20. Okay O (2019) Semicrystalline physical hydrogels with shape-memory and self-healing
properties. J Mater Chem B 7:1581–1596
21. Talebian S, Mehrali M, Taebnia N, Pennisi CP, Kadumudi FB, Foroughi J, Hasany M,
Nikkhah M, Akbari M, Orive G, Dolatshahi-Pirouz A (2019) Self-healing hydrogels: the
next paradigm shift in tissue engineering? Adv Sci 6:1801664. (1–47)
22. Li Q, Liu C, Wen J, Wu Y, Shan Y, Liao J (2017) The design, mechanism and biomedical
application of self-healing hydrogels. Chin Chem Lett 28:1857–1874
23. Strandman S, Zhu XX (2016) Self-healing supramolecular hydrogels based on reversible
physical interactions. Gels 2:16. (1–31)
24. Wang W, Zhang Y, Liu W (2017) Bioinspired fabrication of high strength hydrogels from
non-covalent interactions. Prog Polym Sci 71:1–25
25. Sun TL, Kurokawa T, Kuroda S, Ihsan AB, Akasaki T, Sato K, Haque MA, Nakajima T, Gong
JP (2013) Physical hydrogels composed of polyampholytes demonstrate high toughness and
viscoelasticity. Nat Mater 12:932–937
26. Sun TL, Cui K (2020) Tough and self-healing hydrogels from polyampholytes. Adv Polym Sci
(in press), https://doi.org/10.1007/12_2019_56
27. Bilici C, Can V, Nöchel U, Behl M, Lendlein A, Okay O (2016) Melt-processable shapememory hydrogels with self-healing ability of high mechanical strength. Macromolecules
49:7442–7449
28. Su E, Okay O (2019) A self-healing and highly stretchable polyelectrolyte hydrogel via
cooperative hydrogen-bonding as a superabsorbent polymer. Macromolecules 52:3257–3267
29. Dai X, Zhang Y, Gao L, Bai T, Wang W, Cui Y, Liu W (2015) A mechanically strong, highly
stable, thermoplastic, and self-healable supramolecular polymer hydrogel. Adv Mater
27:3566–3571
30. Wang H, Zhu H, Fu W, Zhang Y, Xu B, Gao F, Cao Z, Liu W (2017) A high strength selfhealable antibacterial and anti-inflammatory supramolecular polymer hydrogel. Macromol
Rapid Commun 38:1600695
31. Tang L, Liu W, Liu G (2010) High-strength hydrogels with integrated functions of H-bonding
and thermoresponsive surface-mediated reverse transfection and cell detachment. Adv Mater
22:2652–2656
32. Gao H, Wang N, Hu X, Nan W, Han Y, Liu W (2013) Double hydrogen-bonding pH-sensitive
hydrogels retaining high-strengths over a wide pH range. Macromol Rapid Commun 34:63–68
33. Maly KE, Dauphin C, Wuest JD (2006) Self-assembly of columnar mesophases from
diaminotriazines. J Mater Chem 16:4695–4700
34. Liu B, Liu W (2018) Poly(vinyl diaminotriazine): from molecular recognition to high-strength
hydrogels. Macromol Rapid Commun 39:1800190
35. Sijbesma RP, Meijer EW (2003) Quadruple hydrogen bonded systems. Chem Commun:5–16
56
O. Okay