50
2 Selective Production of Methanol …
78. Merkx M, Kopp DA, Sazinsky MH, Blazyk JL, Müller J, Lippard SJ (2001) Dioxygen activation and methane hydroxylation by soluble methane monooxygenase: a tale of two irons
and three proteins. Angew Chem Int Ed 40:2782–2807
79. Murray LJ, Lippard SJ (2007) Substrate trafficking and dioxygen activation in bacterial
multicomponent monooxygenases. Acc Chem Res 40:466–474
80. Chang SL, Wallar BJ, Lipscomb JD, Mayo KH (2001) Residues in Methylosinus trichosporium OB3b methane monooxygenase component B involved in molecular interactions with
reduced- and oxidized-hydroxylase component: a role for the N-terminus. Biochemistry
40:9539–9551
81. Conrado RJ, Gonzalez R (2014) Chemistry. Envisioning the bioconversion of methane to
liquid fuels. Science 343:621–623
82. Lieberman LL, Rosenzweig AC (2005) Crystal structure of a membrane-bound metalloenzyme that catalyses the biological oxidation of methane. Nature 434:177–182
83. Hakemian AS, Kondapalli KC, Telser J, Hoffman BM, Stemmler TL, Rosenzweig AC (2008)
The metal centers of particulate methane monooxygenase from Methylosinus trichosporium
OB3b. Biochemistry 47:6793–6801
84. Smith SM, Rawat S, Telser J, Hoffman BM, Stemmler TL, Rosenzweig AC (2011) Crystal
structure and characterization of particulate methane monooxygenase from Methylocystis
species strain M. Biochemistry 50:10231–10240
85. Sirajuddin S, Barupala D, Helling S, Marcus K, Stemmler TL, Rosenzweig AC (2014) Effects
of zinc on particulate methane monooxygenase activity and structure. J Biol Chem 289:21782–
21794
86. Myronova N, Kitmitto A, Collins RF, Miyaji A, Dalton H (2006) Three-dimensional structure determination of a protein supercomplex that oxidizes methane to formaldehyde in
Methylococcus capsulatus (Bath). Biochemistry 45:11905–11914
87. Prior SD, Dalton H (1985) The effect of copper ions on membrane content and methane
monooxygenase activity in methanol-grown cells of Methylococcus capsulatus (Bath). J Gen
Microbiol 131:155–163
88. Cook SA, Shiemke AK (2002) Evidence that a type-2 NADH:quinone oxidoreductase mediates electron transfer to particulate methane monooxygenase in Methylococcus capsulatus.
Arch Biochem Biophys 398:32–40
89. Rosenzweig AC (2008) The metal centres of particulate methane monooxygenase. Biochem
Soc Trans 36:1134–1137
90. Culpepper MA, Rosenzweig AC (2012) Architecture and active site of particulate methane
monooxygenase. Crit Rev Biochem Mol Biol 47:483–492
91. Wang VC, Maji S, Chen PP, Lee HK, Yu SS, Chan SI (2017) Alkane oxidation: methane
monooxygenases, related enzymes, and their biomimetics. Chem Rev 117:8574–8621
92. Cao L, Caldararu O, Rosenzweig AC, Ryde U (2018) Quantum refinement does not support
dinuclear copper sites in crystal structures of particulate methane monooxygenase. Angew
Chem Int Ed 57:162–166
93. Miyaji A, Kamachi T, Okura I (2002) Improvement of the purification method for retaining the
activity of the particulate methane monooxygenase from Methylosinus trichosporium OB3b.
Biotech Lett 24:1883–1887
94. Chan SI, Wang VCC, Lai JCHL, Yu SSF, Chen PPY, Chen KHC, Chen CL, Chan MK (2007)
Redox potentiometry studies of particulate methane monooxygenase: support for a trinuclear
copper cluster active site. Angew Chem Int Ed 46:1992–1994
95. Chan SI, Yu SS (2008) Controlled oxidation of hydrocarbons by the membrane-bound methane
monooxygenase: the case for a tricopper cluster. Acc Chem Res 41:969–979
96. Chan SI, Chen KH, Yu SS, Chen CL, Kuo SS (2004) Toward delineating the structure and function of the particulate methane monooxygenase from methanotrophic bacteria. Biochemistry
43:4421–4430
97. Yu SS, Ji CZ, Wu YP, Lee TL, Lai CH, Lin SC, Yang ZL, Wang VC, Chen KH, Chan
SI (2007) The C-terminal aqueous-exposed domain of the 45 kDa subunit of the particulate
methane monooxygenase in Methylococcus capsulatus (Bath) is a Cu(I) sponge. Biochemistry
46:13762–13774
2 Selective Production of Methanol …
78. Merkx M, Kopp DA, Sazinsky MH, Blazyk JL, Müller J, Lippard SJ (2001) Dioxygen activation and methane hydroxylation by soluble methane monooxygenase: a tale of two irons
and three proteins. Angew Chem Int Ed 40:2782–2807
79. Murray LJ, Lippard SJ (2007) Substrate trafficking and dioxygen activation in bacterial
multicomponent monooxygenases. Acc Chem Res 40:466–474
80. Chang SL, Wallar BJ, Lipscomb JD, Mayo KH (2001) Residues in Methylosinus trichosporium OB3b methane monooxygenase component B involved in molecular interactions with
reduced- and oxidized-hydroxylase component: a role for the N-terminus. Biochemistry
40:9539–9551
81. Conrado RJ, Gonzalez R (2014) Chemistry. Envisioning the bioconversion of methane to
liquid fuels. Science 343:621–623
82. Lieberman LL, Rosenzweig AC (2005) Crystal structure of a membrane-bound metalloenzyme that catalyses the biological oxidation of methane. Nature 434:177–182
83. Hakemian AS, Kondapalli KC, Telser J, Hoffman BM, Stemmler TL, Rosenzweig AC (2008)
The metal centers of particulate methane monooxygenase from Methylosinus trichosporium
OB3b. Biochemistry 47:6793–6801
84. Smith SM, Rawat S, Telser J, Hoffman BM, Stemmler TL, Rosenzweig AC (2011) Crystal
structure and characterization of particulate methane monooxygenase from Methylocystis
species strain M. Biochemistry 50:10231–10240
85. Sirajuddin S, Barupala D, Helling S, Marcus K, Stemmler TL, Rosenzweig AC (2014) Effects
of zinc on particulate methane monooxygenase activity and structure. J Biol Chem 289:21782–
21794
86. Myronova N, Kitmitto A, Collins RF, Miyaji A, Dalton H (2006) Three-dimensional structure determination of a protein supercomplex that oxidizes methane to formaldehyde in
Methylococcus capsulatus (Bath). Biochemistry 45:11905–11914
87. Prior SD, Dalton H (1985) The effect of copper ions on membrane content and methane
monooxygenase activity in methanol-grown cells of Methylococcus capsulatus (Bath). J Gen
Microbiol 131:155–163
88. Cook SA, Shiemke AK (2002) Evidence that a type-2 NADH:quinone oxidoreductase mediates electron transfer to particulate methane monooxygenase in Methylococcus capsulatus.
Arch Biochem Biophys 398:32–40
89. Rosenzweig AC (2008) The metal centres of particulate methane monooxygenase. Biochem
Soc Trans 36:1134–1137
90. Culpepper MA, Rosenzweig AC (2012) Architecture and active site of particulate methane
monooxygenase. Crit Rev Biochem Mol Biol 47:483–492
91. Wang VC, Maji S, Chen PP, Lee HK, Yu SS, Chan SI (2017) Alkane oxidation: methane
monooxygenases, related enzymes, and their biomimetics. Chem Rev 117:8574–8621
92. Cao L, Caldararu O, Rosenzweig AC, Ryde U (2018) Quantum refinement does not support
dinuclear copper sites in crystal structures of particulate methane monooxygenase. Angew
Chem Int Ed 57:162–166
93. Miyaji A, Kamachi T, Okura I (2002) Improvement of the purification method for retaining the
activity of the particulate methane monooxygenase from Methylosinus trichosporium OB3b.
Biotech Lett 24:1883–1887
94. Chan SI, Wang VCC, Lai JCHL, Yu SSF, Chen PPY, Chen KHC, Chen CL, Chan MK (2007)
Redox potentiometry studies of particulate methane monooxygenase: support for a trinuclear
copper cluster active site. Angew Chem Int Ed 46:1992–1994
95. Chan SI, Yu SS (2008) Controlled oxidation of hydrocarbons by the membrane-bound methane
monooxygenase: the case for a tricopper cluster. Acc Chem Res 41:969–979
96. Chan SI, Chen KH, Yu SS, Chen CL, Kuo SS (2004) Toward delineating the structure and function of the particulate methane monooxygenase from methanotrophic bacteria. Biochemistry
43:4421–4430
97. Yu SS, Ji CZ, Wu YP, Lee TL, Lai CH, Lin SC, Yang ZL, Wang VC, Chen KH, Chan
SI (2007) The C-terminal aqueous-exposed domain of the 45 kDa subunit of the particulate
methane monooxygenase in Methylococcus capsulatus (Bath) is a Cu(I) sponge. Biochemistry
46:13762–13774