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62. Brown, D.W., Giles, W.H., Croft, J.B.: White blood cell count: an independent predictor of
coronary heart disease mortality among a national cohort. J. Clin. Epidemiol. 54(3), 316–322
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63. Hou, L., Wang, H., Sartori, S., Gawron, A., Lissowska, J., Bollati, V., Baccarelli, A.: Blood
leukocyte DNA hypomethylation and gastric cancer risk in a high-risk Polish population. Int.
J. Cancer 127(8), 1866–1874 (2010)
64. Hassan, U., Ghonge, T., Reddy Jr., B., Patel, M., Rappleye, M., Taneja, I., Jensen, T.: A
point-of-care microfluidic biochip for quantification of CD64 expression from whole blood
for sepsis stratification. Nat. Commun. 8, 15949 (2017)
65. Cheng, X., Irimia, D., Dixon, M., Sekine, K., Demirci, U., Zamir, L., Toner, M.: A microfluidic
device for practical label-free CD4+ T cell counting of HIV-infected subjects. Lab Chip 7(2),
170–178 (2007)
66. Han, K.H., Frazier, A.B.: Lateral-driven continuous dielectrophoretic microseparators for
blood cells suspended in a highly conductive medium. Lab Chip 8(7), 1079–1086 (2008)
67. Yang, J., Huang, Y., Wang, X.B., Becker, F.F., Gascoyne, P.R.: Differential analysis of human
leukocytes by dielectrophoretic field-flow-fractionation. Biophys. J. 78(5), 2680–2689 (2000)
68. Yang, J., Huang, Y., Wang, X., Wang, X.B., Becker, F.F., Gascoyne, P.R.: Dielectric properties
of human leukocyte subpopulations determined by electrorotation as a cell separation criterion.
Biophys. J. 76(6), 3307–3314 (1999)
69. Urbansky, A., Olm, F., Scheding, S., Laurell, T., Lenshof, A.: Label-free separation of
leukocyte subpopulations using high throughput multiplex acoustophoresis. Lab Chip 19(8),
1406–1416 (2019)
70. Grenvall, C., Magnusson, C., Lilja, H., Laurell, T.: Concurrent isolation of lymphocytes and
granulocytes using prefocused free flow acoustophoresis. Anal. Chem. 87(11), 5596–5604
(2015)
71. Petersson, F., Åberg, L., Swärd-Nilsson, A.M., Laurell, T.: Free flow acoustophoresis:
microfluidic-based mode of particle and cell separation. Anal. Chem. 79(14), 5117–5123
(2007)
72. Han, K.H., Frazier, A.B.: Paramagnetic capture mode magnetophoretic microseparator for
high efficiency blood cell separations. Lab Chip 6(2), 265–273 (2006)
73. Qu, B.Y., Wu, Z.Y., Fang, F., Bai, Z.M., Yang, D.Z., Xu, S.K.: A glass microfluidic chip for
continuous blood cell sorting by a magnetic gradient without labeling. Anal. Bioanal. Chem.
392(7–8), 1317 (2008)
74. Ji, H.M., Samper, V., Chen, Y., Heng, C.K., Lim, T.M., Yobas, L.: Silicon-based microfilters
for whole blood cell separation. Biomed. Microdevice 10(2), 251–257 (2008)
75. Tripathi, A., Riddell IV, J., Chronis, N.: A Biochip with a 3D microfluidic architecture for
trapping white blood cells. Sens. Actuators B: Chem. 186, 244–251 (2013)
76. VanDelinder, V., Groisman, A.: Perfusion in microfluidic cross-flow: separation of white blood
cells from whole blood and exchange of medium in a continuous flow. Anal. Chem. 79(5),
2023–2030 (2007)
77. Alvankarian, J., Bahadorimehr, A., Yeop Majlis, B.: A pillar-based microfilter for isolation
of white blood cells on elastomeric substrate. Biomicrofluidics 7(1), 014102 (2013)
78. Zheng, S., Tai, Y.C., Kasdan, H.: A micro device for separation of erythrocytes and leukocytes
in human blood. In: 27th Annual Conference of the 2005 IEEE Engineering in Medicine and
Biology, pp. 1024–1027 (2006)
79. Sethu, P., Anahtar, M., Moldawer, L.L., Tompkins, R.G., Toner, M.: Continuous flow
microfluidic device for rapid erythrocyte lysis. Anal. Chem. 76(21), 6247–6253 (2004)
80. Chen, J., Chen, D., Yuan, T., Xie, Y., Chen, X.: A microfluidic chip for direct and rapid
trapping of white blood cells from whole blood. Biomicrofluidics 7(3), 034106 (2013)
81. Kim, M., Mo Jung, S., Lee, K.H., Jun Kang, Y., Yang, S.: A microfluidic device for continuous
white blood cell separation and lysis from whole blood. Artif. Organs 34(11), 996–1002 (2010)
82. Shevkoplyas, S.S., Yoshida, T., Munn, L.L., Bitensky, M.W.: Biomimetic autoseparation of
leukocytes from whole blood in a microfluidic device. Anal. Chem. 77(3), 933–937 (2005)
V. Laxmi et al.
62. Brown, D.W., Giles, W.H., Croft, J.B.: White blood cell count: an independent predictor of
coronary heart disease mortality among a national cohort. J. Clin. Epidemiol. 54(3), 316–322
(2001)
63. Hou, L., Wang, H., Sartori, S., Gawron, A., Lissowska, J., Bollati, V., Baccarelli, A.: Blood
leukocyte DNA hypomethylation and gastric cancer risk in a high-risk Polish population. Int.
J. Cancer 127(8), 1866–1874 (2010)
64. Hassan, U., Ghonge, T., Reddy Jr., B., Patel, M., Rappleye, M., Taneja, I., Jensen, T.: A
point-of-care microfluidic biochip for quantification of CD64 expression from whole blood
for sepsis stratification. Nat. Commun. 8, 15949 (2017)
65. Cheng, X., Irimia, D., Dixon, M., Sekine, K., Demirci, U., Zamir, L., Toner, M.: A microfluidic
device for practical label-free CD4+ T cell counting of HIV-infected subjects. Lab Chip 7(2),
170–178 (2007)
66. Han, K.H., Frazier, A.B.: Lateral-driven continuous dielectrophoretic microseparators for
blood cells suspended in a highly conductive medium. Lab Chip 8(7), 1079–1086 (2008)
67. Yang, J., Huang, Y., Wang, X.B., Becker, F.F., Gascoyne, P.R.: Differential analysis of human
leukocytes by dielectrophoretic field-flow-fractionation. Biophys. J. 78(5), 2680–2689 (2000)
68. Yang, J., Huang, Y., Wang, X., Wang, X.B., Becker, F.F., Gascoyne, P.R.: Dielectric properties
of human leukocyte subpopulations determined by electrorotation as a cell separation criterion.
Biophys. J. 76(6), 3307–3314 (1999)
69. Urbansky, A., Olm, F., Scheding, S., Laurell, T., Lenshof, A.: Label-free separation of
leukocyte subpopulations using high throughput multiplex acoustophoresis. Lab Chip 19(8),
1406–1416 (2019)
70. Grenvall, C., Magnusson, C., Lilja, H., Laurell, T.: Concurrent isolation of lymphocytes and
granulocytes using prefocused free flow acoustophoresis. Anal. Chem. 87(11), 5596–5604
(2015)
71. Petersson, F., Åberg, L., Swärd-Nilsson, A.M., Laurell, T.: Free flow acoustophoresis:
microfluidic-based mode of particle and cell separation. Anal. Chem. 79(14), 5117–5123
(2007)
72. Han, K.H., Frazier, A.B.: Paramagnetic capture mode magnetophoretic microseparator for
high efficiency blood cell separations. Lab Chip 6(2), 265–273 (2006)
73. Qu, B.Y., Wu, Z.Y., Fang, F., Bai, Z.M., Yang, D.Z., Xu, S.K.: A glass microfluidic chip for
continuous blood cell sorting by a magnetic gradient without labeling. Anal. Bioanal. Chem.
392(7–8), 1317 (2008)
74. Ji, H.M., Samper, V., Chen, Y., Heng, C.K., Lim, T.M., Yobas, L.: Silicon-based microfilters
for whole blood cell separation. Biomed. Microdevice 10(2), 251–257 (2008)
75. Tripathi, A., Riddell IV, J., Chronis, N.: A Biochip with a 3D microfluidic architecture for
trapping white blood cells. Sens. Actuators B: Chem. 186, 244–251 (2013)
76. VanDelinder, V., Groisman, A.: Perfusion in microfluidic cross-flow: separation of white blood
cells from whole blood and exchange of medium in a continuous flow. Anal. Chem. 79(5),
2023–2030 (2007)
77. Alvankarian, J., Bahadorimehr, A., Yeop Majlis, B.: A pillar-based microfilter for isolation
of white blood cells on elastomeric substrate. Biomicrofluidics 7(1), 014102 (2013)
78. Zheng, S., Tai, Y.C., Kasdan, H.: A micro device for separation of erythrocytes and leukocytes
in human blood. In: 27th Annual Conference of the 2005 IEEE Engineering in Medicine and
Biology, pp. 1024–1027 (2006)
79. Sethu, P., Anahtar, M., Moldawer, L.L., Tompkins, R.G., Toner, M.: Continuous flow
microfluidic device for rapid erythrocyte lysis. Anal. Chem. 76(21), 6247–6253 (2004)
80. Chen, J., Chen, D., Yuan, T., Xie, Y., Chen, X.: A microfluidic chip for direct and rapid
trapping of white blood cells from whole blood. Biomicrofluidics 7(3), 034106 (2013)
81. Kim, M., Mo Jung, S., Lee, K.H., Jun Kang, Y., Yang, S.: A microfluidic device for continuous
white blood cell separation and lysis from whole blood. Artif. Organs 34(11), 996–1002 (2010)
82. Shevkoplyas, S.S., Yoshida, T., Munn, L.L., Bitensky, M.W.: Biomimetic autoseparation of
leukocytes from whole blood in a microfluidic device. Anal. Chem. 77(3), 933–937 (2005)