6 Managing Thermal History to Stabilize/Destabilize …
111
28. Aso, Y., Yoshioka, S., Kojima, S.: Relationship between the crystallization rates of amorphous
nifedipine, phenobarbital, and flopropione, and their molecular mobility as measured by their
enthalpy relaxation and 1H NMR relaxation times. J. Pharm. Sci. 89, 408–416 (2000)
29. Kothari, K., Ragoonanan, V., Suryanarayanan, R.: The role of polymer concentration on the
molecular mobility and physical stability of nifedipine solid dispersions. Mol. Pharm. 12,
1477–1484 (2015)
30. Aso, Y., Yoshioka, S., Kojima, S.: Molecular mobility-based estimation of the crystallization
rates of amorphous nifedipine and phenobarbital in poly(vinylpyrrolidone) solid dispersions.
J. Pharm. Sci. 93, 384–391 (2004)
31. Caron, V., Bhugra, C., Pikal, M.J.: Prediction of onset of crystallization in amorphous pharmaceutical systems: phenobarbital, nifedipine/PVP, and phenobarbital/PVP. J. Pharm. Sci. 99,
3887–3900 (2010)
32. Greco, S., Authelin, J.R., Leveder, C., Segalini, A.: A practical method to predict physical
stability of amorphous solid dispersions. Mol. Pharm. 29, 2792–2805 (2012)
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