5 Cardio-oncology: Network-Based Prediction …
81
Table 5.1 (continued)
Name of
databases
Description
The number of
interactions,
drugs, and targets
Web site
References
STITCH
Experimental and
predicted
compoundprotein
interactions
1.6 billion
interactions
connecting 0.5
million
compounds and
9.6 million
proteins from
2031 organisms
http://stitch.embl.
de/
[102]
SuperPred
Experimental and
predicted
compoundprotein
interactions
341,000
compounds, 1800
targets and
665,000
compound-target
interactions
http://prediction.
charite.de/index.
php
[103]
Section 2. Databases for collecting functional drug-gene interactions
CMap (v 2.0)
Gene-expression
signatures to
connect 1309
small molecules
and ~7000 genes
in 4 cancer cell
lines
https://www.
broadinstitute.
org/cmap
[104]
LINCS
Library of
integrated
network-based
cellular
signatures
for ~1 million of
gene expression
profiles
http://www.
lincscloud.org/
[105]
open TG-GATEs
A large-scale
toxicogenomics
database
http://toxico.
nibio.go.jp/
english/index.
html
[106]
DrugMatrix
Molecular
toxicology
reference
database and
informatics
system
http://ntp.niehs.
nih.gov/
drugmatrix/index.
html
[107]