402
B. Hardy et al.
18. EUR-Lex—02006R1907-20140410—EN—EUR-Lex. Retrieved from http://eur-lex.europa.
eu/legal-content/EN/TXT/?uri=CELEX%3A02006R1907-20140410. Accessed on 30 Mar
2017
19. OECD series on testing and assessment, books/OECD series on testing and assessment/ N°69—guidance document on the validation of (quantitative) structure-activity
relationship [(Q)SAR] models. Retrieved from http://www.oecd-ilibrary.org/docserver/
download/9750691e.pdf?expires=1490892571&id=id&accname=guest&checksum=
23D26D174819D41691EDC490EAA82326
20. OECD (2016) Retrieved from http://www.oecd.org/officialdocuments/publicdisplaydocumentpdf/?cote=env/jm/mono(2016)67&doclanguage=en. Accessed on 30 Mar 2017
21. Tollefsen KE et al. Applying adverse outcome pathways (AOPs) to support integrated
approaches to testing and assessment (IATA). PubMed—NCBI. Retrieved from https://www.
ncbi.nlm.nih.gov/pubmed/25261300. Accessed on 30 Mar 2017
Barry Hardy is leading Douglas Connect and its team supports the development of new integrating solutions in industrial safety assessment. An example application is that for integrated testing
for skin sensitization available at https://its.douglasconnect.com/. He has coordinated the OpenTox
project in predictive toxicology and the ToxBank infrastructure development project. He is currently President of the OpenTox Association, founded in 2015 as an international non-profit organization promoting an open knowledge community approach to new methods in predictive toxicology. He recently led the infrastructure development for the IMI EBiSC stem cell banking project
and the eNanoMapper project developing OpenTox solutions supporting nanotechnology safety
assessment. New projects include leading OpenRiskNet, knowledge infrastructure development
for ACEnano and Eu-ToxRisk and translation of research methods to industrial practice within
ToxHQ. He has led the development of research and best practice activities in drug design and
toxicology through founding the eCheminfo Community of Practice, InnovationWell and leading
the Scientists Against Malaria project. He obtained his Ph.D. in 1990 from Syracuse University
working in computational science. He was National Research Fellow at the FDA Center for Biologics and Evaluation, Hitchings-Elion Fellow at Oxford University, and CEO of Virtual Environments International.
Daniel Bachler is Senior Software Engineer at Douglas Connect and is specialized in data integration and software container technologies with a focus on reproducibility of scientific software
methods. He has worked in different fields from high-performance statistics applications to sensitive data processing pipelines and is highly skilled in many database technologies as well as
moderns cloud deployment solutions. He has a strong interest in designing and developing highly
maintainable and reliable software solutions by employing purely functional programming languages.
Joh Dokler is Chief Technology Officer (CTO) at Douglas Connect, architecting and developing
Web-based solutions. He met the Web in the early 1990 at the Josef Stefan Institute in Ljubljana,
Slovenia. Since then he successfully completed more than 100 commercial, academic, and government Web projects. He combines his software development skills with his expertise as an information architect to develop sound, solid, and data-driven Web solutions. He initially studied physics
at University of Ljubljana and later obtained his MSc in computing and software engineering at
Open University, UK.
Thomas Exner is Chief Scientific Officer (CSO) at Douglas Connect. He studied chemistry and
did his Ph.D. at the Technische Universität Darmstadt followed by a postdoc at the University
of Saskatchewan, Canada. After 12 years of independent academic research (University of Konstanz and University of Tübingen), he joined the Douglas Connect team in 2015. In April 2016, he
B. Hardy et al.
18. EUR-Lex—02006R1907-20140410—EN—EUR-Lex. Retrieved from http://eur-lex.europa.
eu/legal-content/EN/TXT/?uri=CELEX%3A02006R1907-20140410. Accessed on 30 Mar
2017
19. OECD series on testing and assessment, books/OECD series on testing and assessment/ N°69—guidance document on the validation of (quantitative) structure-activity
relationship [(Q)SAR] models. Retrieved from http://www.oecd-ilibrary.org/docserver/
download/9750691e.pdf?expires=1490892571&id=id&accname=guest&checksum=
23D26D174819D41691EDC490EAA82326
20. OECD (2016) Retrieved from http://www.oecd.org/officialdocuments/publicdisplaydocumentpdf/?cote=env/jm/mono(2016)67&doclanguage=en. Accessed on 30 Mar 2017
21. Tollefsen KE et al. Applying adverse outcome pathways (AOPs) to support integrated
approaches to testing and assessment (IATA). PubMed—NCBI. Retrieved from https://www.
ncbi.nlm.nih.gov/pubmed/25261300. Accessed on 30 Mar 2017
Barry Hardy is leading Douglas Connect and its team supports the development of new integrating solutions in industrial safety assessment. An example application is that for integrated testing
for skin sensitization available at https://its.douglasconnect.com/. He has coordinated the OpenTox
project in predictive toxicology and the ToxBank infrastructure development project. He is currently President of the OpenTox Association, founded in 2015 as an international non-profit organization promoting an open knowledge community approach to new methods in predictive toxicology. He recently led the infrastructure development for the IMI EBiSC stem cell banking project
and the eNanoMapper project developing OpenTox solutions supporting nanotechnology safety
assessment. New projects include leading OpenRiskNet, knowledge infrastructure development
for ACEnano and Eu-ToxRisk and translation of research methods to industrial practice within
ToxHQ. He has led the development of research and best practice activities in drug design and
toxicology through founding the eCheminfo Community of Practice, InnovationWell and leading
the Scientists Against Malaria project. He obtained his Ph.D. in 1990 from Syracuse University
working in computational science. He was National Research Fellow at the FDA Center for Biologics and Evaluation, Hitchings-Elion Fellow at Oxford University, and CEO of Virtual Environments International.
Daniel Bachler is Senior Software Engineer at Douglas Connect and is specialized in data integration and software container technologies with a focus on reproducibility of scientific software
methods. He has worked in different fields from high-performance statistics applications to sensitive data processing pipelines and is highly skilled in many database technologies as well as
moderns cloud deployment solutions. He has a strong interest in designing and developing highly
maintainable and reliable software solutions by employing purely functional programming languages.
Joh Dokler is Chief Technology Officer (CTO) at Douglas Connect, architecting and developing
Web-based solutions. He met the Web in the early 1990 at the Josef Stefan Institute in Ljubljana,
Slovenia. Since then he successfully completed more than 100 commercial, academic, and government Web projects. He combines his software development skills with his expertise as an information architect to develop sound, solid, and data-driven Web solutions. He initially studied physics
at University of Ljubljana and later obtained his MSc in computing and software engineering at
Open University, UK.
Thomas Exner is Chief Scientific Officer (CSO) at Douglas Connect. He studied chemistry and
did his Ph.D. at the Technische Universität Darmstadt followed by a postdoc at the University
of Saskatchewan, Canada. After 12 years of independent academic research (University of Konstanz and University of Tübingen), he joined the Douglas Connect team in 2015. In April 2016, he