284
R. Huang
Table 14.1 (continued)
Assay
Assay name
PubChem AID
Reproducibility score
GR-BLA agonist
Glucocorticoid
receptor, agonist
mode
720691, 720719
94.89
GR-BLA antagonist
Glucocorticoid
receptor, antagonist
mode
720692, 720725,
720693
77.40
PPAR-delta-BLA
agonist
Peroxisome
proliferator-activated
receptor delta,
agonist mode
743212, 743227,
743211
91.91
PPAR-delta-BLA
antagonist
Peroxisome
proliferator-activated
receptor delta,
antagonist mode
743215, 743226,
743213
90.37
PPAR-gamma
agonist
peroxisome
proliferator-activated
receptor gamma,
agonist mode
743094, 743140
93.81
PPAR-gamma
antagonist
Peroxisome
proliferator-activated
receptor gamma,
antagonist mode
743191, 743199,
743194
85.15
RAR agonist
Retinoic acid
receptor, agonist
mode
1159553
89.15
RAR antagonist
Retinoic acid
receptor, antagonist
mode
1159552
71.50
ROR antagonist
Retinoid-related
orphan receptor
gamma, antagonist
mode
1159521
72.95
RXR-BLA agonist
Retinoid X receptor,
agonist mode
1159527, 1159529,
1159531
79.20
TR-beta agonist
Thyroid hormone
receptor, agonist
mode
743066
87.84
TR-beta antagonist
Thyroid hormone
receptor, antagonist
mode
743065, 743067,
743064
87.82
VDR-BLA agonist
Vitamin D receptor,
agonist mode
743222, 743241,
743224
91.79
(continued)