Arabidopsis thaliana populations in Patagonia,
Argentina. Mol Ecol 26:3389–3404
9. Manda ´kova ´ T, Thorbjo ¨rnsson H, Pisupati R
et al (2017) Icelandic accession of Arabidopsis
thaliana confirmed with cytogenetic markers
and its origin inferred from whole-genome
sequencing. Icel Agric Sci 30:29–38
10. Exposito-Alonso M, Becker C, Schuenemann
VJ et al (2018) The rate and potential relevance
of new mutations in a colonizing plant lineage.
PLoS Genet 14(2):e1007155
11. Alonso-Blanco C, Koornneef M, van Ooijen
JW (2006) QTL analysis. In: Salinas J,
Sanchez-Serrano JJ (eds) Arabidopsis protocols, 2nd edn. Humana Press, Totowa
12. Wijnen CL, Keurentjes JJ (2014) Genetic
resources for quantitative trait analysis: novelty
and efficiency in design from an Arabidopsis
perspective. Curr Opin Plant Biol 18:103–109
13. Bazakos C, Hanemian M, Trontin C et al
(2017) New strategies and tools in quantitative
genetics: how to go from the phenotype to the
genotype. Annu Rev Plant Biol 68:435–455
14. Alonso-Blanco C, Aarts MG, Bentsink L et al
(2009) What has natural variation taught us
about plant development, physiology, and
adaptation? Plant Cell 21:1877–1896
15. Alonso-Blanco C, Mendez-Vigo B (2014)
Genetic architecture of naturally occurring
quantitative traits in plants: an updated synthesis. Curr Opin Plant Biol 18:37–43
16. Martin A, Orgogozo V (2013) The loci of
repeated evolution: a catalog of genetic hotspots of phenotypic variation. Evolution
67:1235–1250
17. Barboza L, Effgen S, Alonso-Blanco C et al
(2013) Arabidopsis semidwarfs evolved from
independent mutations in GA20ox1, ortholog
to green revolution dwarf alleles in rice and
barley. Proc Natl Acad Sci U S A
110:15818–15823
18. Durvasula A, Fulgione A, Gutaker RM et al
(2017) African genomes illuminate the early
history and transition to selfing in Arabidopsis
thaliana. Proc Natl Acad Sci U S A
114:5213–5218
19. Fulgione A, Koornneef M, Roux F et al (2017)
Madeiran Arabidopsis thaliana reveals ancient
long-range colonization and clarifies demography in Eurasia. Mol Biol Evol 35:564–574
20. Zou YP, Hou XH, Wu Q et al (2017) Adaptation of Arabidopsis thaliana to the Yangtze
River basin. Genome Biol 18:239
21. Hsu CW, Lo CY, Lee CR (2019) On the postglacial spread of human commensal Arabidopsis
thaliana: journey to the East. New Phytol
222:1447–1457
22. 1001 Genomes Consortium Group (2016)
1,135 genomes reveal the global pattern of
polymorphism in Arabidopsis thaliana. Cell
166:481–491
23. Lee CR, Svardal H, Farlow A et al (2017) On
the post-glacial spread of human commensal
Arabidopsis thaliana. Nat Commun 8:14458
24. Wilczek AM, Roe JL, Knapp MC et al (2009)
Effects of genetic perturbation on seasonal life
history plasticity. Science 323:930–934
25. Chiang GC, Barua D, Dittmar E et al (2013)
Pleiotropy in the wild: the dormancy gene
DOG1 exerts cascading control on life cycles.
Evolution 67:883–893
26. Kerdaffrec E, Filiault DL, Korte A et al (2016)
Multiple alleles at a single locus control seed
dormancy in Swedish Arabidopsis. elife 5:
e22502
27. Kerwin RE, Feusier J, Muok A et al (2017)
Epistasis x environment interactions among
Arabidopsis thaliana glucosinolate genes
impact complex traits and fitness in the field.
New Phytol 215:1249–1263
28. Malmberg RL, Held S, Waits A et al (2005)
Epistasis for fitness-related quantitative traits in
Arabidopsis thaliana grown in the field and in
the greenhouse. Genetics 171:2013–2027
29. Brachi B, Faure N, Horton M et al (2010)
Linkage and association mapping of Arabidopsis thaliana flowering time in nature. PLoS
Genet 6:e1000940
30. Oakley CG, Agren J, Atchison RA et al (2014)
QTL mapping of freezing tolerance: links to
fitness and adaptive trade-offs. Mol Ecol
23:4304–4315
31. Postma FM, Agren J (2016) Early life stages
contribute strongly to local adaptation in Arabidopsis thaliana. Proc Natl Acad Sci U S A
113:7590–7595
32. Price N, Moyers BT, Lopez L et al (2018)
Combining population genomics and fitness
QTLs to identify the genetics of local adaptation in Arabidopsis thaliana. Proc Natl Acad
Sci U S A 115:5028–5033
33. Hepworth J, Antoniou-Kourounioti RL,
Bloomer RH et al (2018) Absence of warmth
permits epigenetic memory of winter in Arabidopsis. Nat Commun 9:639
34. Fournier-Level A, Korte A, Cooper MD et al
(2011) A map of local adaptation in Arabidopsis thaliana. Science 334:86–89
35. Mendez-Vigo B, Gomaa NH, Alonso-Blanco
C et al (2013) Among- and within-population
variation in flowering time of Iberian Arabidopsis thaliana estimated in field and glasshouse
conditions. New Phytol 197:1332–1343
110
Carlos Alonso-Blanco et al.
Argentina. Mol Ecol 26:3389–3404
9. Manda ´kova ´ T, Thorbjo ¨rnsson H, Pisupati R
et al (2017) Icelandic accession of Arabidopsis
thaliana confirmed with cytogenetic markers
and its origin inferred from whole-genome
sequencing. Icel Agric Sci 30:29–38
10. Exposito-Alonso M, Becker C, Schuenemann
VJ et al (2018) The rate and potential relevance
of new mutations in a colonizing plant lineage.
PLoS Genet 14(2):e1007155
11. Alonso-Blanco C, Koornneef M, van Ooijen
JW (2006) QTL analysis. In: Salinas J,
Sanchez-Serrano JJ (eds) Arabidopsis protocols, 2nd edn. Humana Press, Totowa
12. Wijnen CL, Keurentjes JJ (2014) Genetic
resources for quantitative trait analysis: novelty
and efficiency in design from an Arabidopsis
perspective. Curr Opin Plant Biol 18:103–109
13. Bazakos C, Hanemian M, Trontin C et al
(2017) New strategies and tools in quantitative
genetics: how to go from the phenotype to the
genotype. Annu Rev Plant Biol 68:435–455
14. Alonso-Blanco C, Aarts MG, Bentsink L et al
(2009) What has natural variation taught us
about plant development, physiology, and
adaptation? Plant Cell 21:1877–1896
15. Alonso-Blanco C, Mendez-Vigo B (2014)
Genetic architecture of naturally occurring
quantitative traits in plants: an updated synthesis. Curr Opin Plant Biol 18:37–43
16. Martin A, Orgogozo V (2013) The loci of
repeated evolution: a catalog of genetic hotspots of phenotypic variation. Evolution
67:1235–1250
17. Barboza L, Effgen S, Alonso-Blanco C et al
(2013) Arabidopsis semidwarfs evolved from
independent mutations in GA20ox1, ortholog
to green revolution dwarf alleles in rice and
barley. Proc Natl Acad Sci U S A
110:15818–15823
18. Durvasula A, Fulgione A, Gutaker RM et al
(2017) African genomes illuminate the early
history and transition to selfing in Arabidopsis
thaliana. Proc Natl Acad Sci U S A
114:5213–5218
19. Fulgione A, Koornneef M, Roux F et al (2017)
Madeiran Arabidopsis thaliana reveals ancient
long-range colonization and clarifies demography in Eurasia. Mol Biol Evol 35:564–574
20. Zou YP, Hou XH, Wu Q et al (2017) Adaptation of Arabidopsis thaliana to the Yangtze
River basin. Genome Biol 18:239
21. Hsu CW, Lo CY, Lee CR (2019) On the postglacial spread of human commensal Arabidopsis
thaliana: journey to the East. New Phytol
222:1447–1457
22. 1001 Genomes Consortium Group (2016)
1,135 genomes reveal the global pattern of
polymorphism in Arabidopsis thaliana. Cell
166:481–491
23. Lee CR, Svardal H, Farlow A et al (2017) On
the post-glacial spread of human commensal
Arabidopsis thaliana. Nat Commun 8:14458
24. Wilczek AM, Roe JL, Knapp MC et al (2009)
Effects of genetic perturbation on seasonal life
history plasticity. Science 323:930–934
25. Chiang GC, Barua D, Dittmar E et al (2013)
Pleiotropy in the wild: the dormancy gene
DOG1 exerts cascading control on life cycles.
Evolution 67:883–893
26. Kerdaffrec E, Filiault DL, Korte A et al (2016)
Multiple alleles at a single locus control seed
dormancy in Swedish Arabidopsis. elife 5:
e22502
27. Kerwin RE, Feusier J, Muok A et al (2017)
Epistasis x environment interactions among
Arabidopsis thaliana glucosinolate genes
impact complex traits and fitness in the field.
New Phytol 215:1249–1263
28. Malmberg RL, Held S, Waits A et al (2005)
Epistasis for fitness-related quantitative traits in
Arabidopsis thaliana grown in the field and in
the greenhouse. Genetics 171:2013–2027
29. Brachi B, Faure N, Horton M et al (2010)
Linkage and association mapping of Arabidopsis thaliana flowering time in nature. PLoS
Genet 6:e1000940
30. Oakley CG, Agren J, Atchison RA et al (2014)
QTL mapping of freezing tolerance: links to
fitness and adaptive trade-offs. Mol Ecol
23:4304–4315
31. Postma FM, Agren J (2016) Early life stages
contribute strongly to local adaptation in Arabidopsis thaliana. Proc Natl Acad Sci U S A
113:7590–7595
32. Price N, Moyers BT, Lopez L et al (2018)
Combining population genomics and fitness
QTLs to identify the genetics of local adaptation in Arabidopsis thaliana. Proc Natl Acad
Sci U S A 115:5028–5033
33. Hepworth J, Antoniou-Kourounioti RL,
Bloomer RH et al (2018) Absence of warmth
permits epigenetic memory of winter in Arabidopsis. Nat Commun 9:639
34. Fournier-Level A, Korte A, Cooper MD et al
(2011) A map of local adaptation in Arabidopsis thaliana. Science 334:86–89
35. Mendez-Vigo B, Gomaa NH, Alonso-Blanco
C et al (2013) Among- and within-population
variation in flowering time of Iberian Arabidopsis thaliana estimated in field and glasshouse
conditions. New Phytol 197:1332–1343
110
Carlos Alonso-Blanco et al.